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Keyword: bonemarrow

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  • New leukemia treament exceeds 'wildest expectations'

    08/10/2011 1:39:34 PM PDT · by Nachum · 68 replies
    NBC News ^ | 8/10/11 | Robert Bazell
    Doctors have treated only three leukemia patients, but the sensational results from a single shot could be one of the most significant advances in cancer research in decades. And it almost never happened. In the research published Wednesday, doctors at the University of Pennsylvania say the treatment made the most common type of leukemia completely disappear in two of the patients and reduced it by 70 percent in the third. In each of the patients as much as five pounds of cancerous tissue completely melted away in a few weeks, and a year later it is still gone
  • Football Player Donates Stem Cells, Saves Life

    12/20/2010 8:53:23 PM PST · by Coleus · 7 replies · 1+ views
    cbs ^ | 12.17.10 | Wyatt Andrews
    A good athlete is often called on to save a game. This is the story of a star football player who was asked to save a life of someone he didn't even know. CBS News correspondent Wyatt Andrews has the latest example of "The American Spirit." There were four finalists last night for the Gagliardi Trophy, basically the Heisman for Division III college football. But for finalist Matt Hoffman learning if he'd win wasn't the suspense of the night.  Meeting cancer patient Warren Sallach was.  Last year Matt donated his bone stem cells - in an anonymous donation that went...
  • A Lifesaver Out of Reach, for Want of a Profit

    10/20/2009 7:42:57 PM PDT · by grey_whiskers · 12 replies · 588+ views
    The New York Times ^ | October 16, 2009 | Jim Dwyer
    Scrambling to get 60 seconds out of every minute, Katie Meacham finally got the boyfriend to take her for a carriage ride in Central Park. He hated it, she reports. “He said, ‘You know this is a pity ride, don’t you?’ ” she said, laughing. Even though she is just 26, her days and time are at a premium. Ms. Meacham lives on the Upper East Side of Manhattan, but she is also a citizen of another country: cancer land. She has a kind of aggressive lymphoma, a disease that ruins the blood.
  • Mixed-race patients struggle to find marrow donors

    05/29/2009 5:35:18 PM PDT · by Bushwacker777 · 9 replies · 1,349+ views
    Yahoo News ^ | May 27 | JULIANA BARBASSA
    "HAYWARD, Calif. – If Nick Glasgow were white, he would have a nearly 90 percent chance of finding a matching bone marrow donor who could cure his leukemia. But because the 28-year-old bodybuilder is one-quarter Japanese, his doctor warned him the outlook was grim. Glasgow's background would make it almost impossible to find a match, which usually comes from a patient's own ethnic group. The doctor "didn't say it was slim-to-none. He didn't say it would be hard. He said 'zero chance,'" Glasgow's mother, Carole Wiegand, recalled with tears in her eyes. "When Nick heard that, it sent him plummeting."...
  • New cancer-killing method found in stem cells, cells showing potential in cancer fight

    05/19/2009 9:36:36 PM PDT · by Coleus · 17 replies · 1,261+ views
    msnbc ^ | 05.19.09
    Genetically engineered stem cells from bone marrow showed promise as a potential new way to deliver a cancer-killing protein to tumors, British researchers said on Tuesday. Experiments in cell cultures and in mice showed the adult stem cells — a type known as mesenchymal stem cells — could home in on cancer cells and deliver a lethal protein that attacked only the cancer while sparing normal healthy tissue. “We’ve developed cells which specifically target cancer through the body and deliver an anti-cancer protein to where it is needed in a seek-and-destroy approach,” said Dr. Michael Loebinger of University College London,...
  • Stem cells help save man's leg from amputation

    02/07/2009 5:40:35 PM PST · by Coleus · 13 replies · 446+ views
    timesofindia ^ | 02.06.09
    CHENNAI: Adult stem cells extracted from the patient’s bone marrow have been found to cure several ailments, but a therapy for regeneration of blood vessles hold out bigger hopes. The department of vascular surgery at the Sri Ramachandra Medical College Hospital and Research Institute in December 2007 has used adult stem cells to trigger growth of new blood vessels in the limbs of at least 30 patients who suffer from critical limb ischemia — a condition of blood vessels in the limb getting blocked, often resulting in amputation. When SRMC doctors told a 64-year-old diabetic patient in December, 2007 that...
  • Adult Stem Cells Successfully Reset Immune System for Multiple Sclerosis Patients

    01/31/2009 3:30:36 AM PST · by GonzoII · 22 replies · 1,214+ views
    LifeNews ^ | January 29, 2009 | Steven Ertelt
    Adult Stem Cells Successfully Reset Immune System for Multiple Sclerosis Patients by Steven Editor January 29, 2009 Chiacgo, IL ( -- Adult stem cells continue to outpace their embryonic counterparts by successfully treating patients with a variety of diseases and conditions. Now, the use of adult stem cells from bone marrow has helped patients suffering from the early stages of multiple sclerosis.A new study shows a research team appears to have reversed the neurological dysfunction of early-stage multiple sclerosis patients by transplanting their own immune stem cells into their bodies and thereby "resetting" their immune systems.Dr. Robert Burt,...
  • Adult Stem Cells Help Repair Man's Back

    06/30/2008 10:04:48 PM PDT · by Coleus · 1 replies · 121+ views
    Citizen Link ^ | 06.09.08
    A spinal surgeon in Aurora, Colo., recently performed what's being called the first disc surgery in the United States using adult stem cells to help repair a man's injured lower back. "Stem cells have shown great promise over the past three years for treating back pain," Dr. Jeffrey Kleiner said. "In combination with the diskectomy, we hope to offer patients long-term relief from their back pain and to decrease their risk of needing additional surgeries." Adult stem cells have been injected into patients' backs and joints to promote tissue growth, but this is the first time stem cells have been...
  • Adult Stem Cells to treat ALS

    06/29/2008 7:40:45 PM PDT · by Coleus · 9 replies · 1,595+ views
    exacom ^ | 05.27.08
    Adult Stem Cells to treat ALS: UBC Study Vancouver researchers pioneer safe pathway to slow ALS using stem cells A unique pilot study has established a safe pathway for using bone-marrow stem cells to slow down and potentially treat Amyotrophic Lateral Sclerosis (ALS), a fatal neurodegenerative disease without cure. The study, published in the journal, Muscle & Nerve and led by Dr. Neil Cashman, professor of neurology at The University of British Columbia and director of the ALS program at Vancouver Coastal Health and VCH Research Institute, tested the use of a growth factor stimulant in ALS patients and found...
  • Researchers to test "Adult" stem cells to treat Crohn's

    06/18/2008 10:03:23 PM PDT · by Coleus · 2 replies · 186+ views
    newsday ^ | 06.17.08 | DELTHIA RICKS
    Stem cells may force Crohn's disease into retreat, say Long Island medical investigators who are embarking on a pioneering analysis that targets patients who've failed other therapies. Cases of Crohn's disease have skyrocketed since World War II, jumping tenfold in the United States and raising questions about the disease's genetics and demography. It is one of two disorders -- the other is ulcerative colitis -- that are known as inflammatory bowel diseases. Before the 20th century there was no recorded evidence of either. Dr. Robert Richards, director of clinical research in the gastroenterology division at Stony Brook University Medical Center,...
  • Innovative Research Advances Stem Cell and Bone Marrow Transplantation

    12/10/2007 10:05:15 PM PST · by Coleus · 43+ views ^ | Mon, 10 Dec 2007 | American Society of Hematology
    ATLANTA, Dec. 10  /PRNewswire-USNewswire/ -- New data being presented at the 49th Annual Meeting of the American Society of Hematology in Atlanta, GA, suggest innovative strategies to improve the success of stem cell and bone marrow transplantation. These studies demonstrate improved outcomes using a new treatment regimen for children with a specific form of leukemia; new ways to increase the number of specialized stem cells harvested from the bone marrow prior to transplantation; efforts to effectively expand stem cell transplantation among patients older than 55; and preclinical research that re-examines the way physicians prepare a patient's immune system to accept...
  • Sacramento man with a spinal injury looks to stem cells harvested from bone marrow to finally end

    12/09/2007 7:41:49 PM PST · by Coleus · 2 replies · 63+ views
    The Sacramento Bee ^ | December 8, 2007 | Dorsey Griffith
    Sacramento man with a spinal injury looks to stem cells harvested from bone marrow to finally end his crippling pain   Dr. Pasquale Montesano, operating Thursday at Sutter Memorial Hospital, shapes a piece of bone that he will fill with adult stem cells harvested from donor cadavers, then place into the spine of Perry Anderson. The hope is that the surgery will help Anderson finally heal from earlier spinal surgery. Bryan Patrick / See additional images They are not from human embryos, but the stem cells being packed into Perry Anderson's spine may help him heal from a surgery...
  • Transplants Without Tears

    11/27/2007 11:19:37 PM PST · by neverdem · 7 replies · 238+ views
    ScienceNOW Daily News ^ | 26 November 2007 | Mitch Leslie
    Heading home. A glowing stem cell transplant searches out a place to settle down.Credit: Deepta Bhattacharya, Agnieszka Czechowicz, and Irving Weissman A new treatment might allow patients to avoid some of the grueling side effects of bone marrow transplants. Researchers reported in the 23 November issue of Science that they can use a specific type of antibody to clear away old marrow stem cells in mice, allowing fresh ones to take their place. The discovery could allow patients to receive bone marrow without undergoing chemotherapy and other toxic procedures. Bone marrow transplants can ameliorate diseases such as sickle cell anemia...
  • Researchers say stem cells can help treat heart failure

    11/27/2007 9:49:42 PM PST · by Coleus · 2 replies · 67+ views
    Worcester Telegram ^ | November 8, 2007 | Rob Waters
    Advanced Cell Technology Inc.’s Mytogen unit said stem cells taken from the thigh muscles of heart failure patients and injected into their damaged organs improved symptoms and cardiac pumping ability a year later. Twenty-three patients who had heart attacks got either their own stem cells or standard state-of-the-art therapy. After one year, the patients injected with cells were able to walk and exert themselves mildly without shortness of breath. Their swollen hearts had shrunk, the study found. The trial by Los Angeles-based Advanced Cell is one of three reported yesterday at the annual meeting of the American Heart Association in...
  • The Good News Just Keeps On Coming: Adult Stem Cells Treat MS and Arthritis in Mice

    11/26/2007 8:14:24 PM PST · by Coleus · 131+ views
    Wesley J. Smith ^ | November 22, 2007 | Wesley J. Smith
    As we celebrate the creation and potential of induced Pluripotent Stem Cells, adult stem cell research continues to bear fruit in animal and human studies. The latest is a truly exciting find out of Stanford University: Blood stem cells taken from a donor with a healthy immune system effectively treated multiple sclerosis and arthritis in mice. From the story in the Telegraph: Thousands of patients with arthritis and multiple sclerosis are given new hope today by scientists who have developed a way to alter the immune system.Both conditions are caused when the immune system becomes faulty and attacks the body....
  • Hope for safer bone marrow transplants

    11/26/2007 7:54:23 PM PST · by Coleus · 108+ views
    Guardian News ^ | November 23 2007 | Ian Sample
    Patients with common immune disorders such as multiple sclerosis and rheumatoid arthritis could one day be treated with bone marrow transplants, scientists claimed yesterday. Hopes for the new treatment follow the development of a more efficient transplant technique which avoids the need for radio- or chemotherapy, both of which have potentially dangerous side-effects. Traditional bone marrow transplants are used to treat only life-threatening conditions, such as leukaemia or lymphoma. The treatment infuses healthy adult stem cells into the patient, which then form fresh blood and immune cells. But before the transplant can be done, patients must receive a course of...
  • Researchers make stem cell breakthrough

    11/06/2007 9:40:09 PM PST · by neverdem · 3 replies · 65+ views
    The Globe and Mail ^ | November 4, 2007 | NA
    Canadian Press TORONTO — Scientists at Toronto's Hospital for Sick Children say they've taken a step forward in stem-cell transplant research. They've discovered a gene with properties that allow for successful transfer of stem cells from human bone marrow into mice. They also identified the type of cell that expresses the gene (called SIRPalpha) and is responsible for either destroying or supporting growth of human blood stem cells. The researchers hope further studies will lead to the development of a therapy so more children with blood diseases can receive bone marrow transplantation. It may also help provide a genetic test...
  • Michigan Bishops Launch Massive Statewide Stem Cell Education Program - Video Online

    10/06/2007 10:42:51 PM PDT · by monomaniac · 202+ views ^ | October 3, 2007
    Michigan Bishops Launch Massive Statewide Stem Cell Education Program - Video Online 12 minute DVD and other material being sent to over 500,000 Catholic homes and nearly 800 parishes LANSING, October 3, 2007 ( - In an effort to communicate the Catholic Church's teaching on human life as it relates to adult and embryonic stem cell research, the Michigan Catholic Conference on Monday announced the state's seven diocesan bishops have launched a monumental internal education program that includes over 500,000 Catholic homes and nearly 800 parishes. As part of the internal education program, which has the theme "The Science of...
  • New liver without transplant, from bone marrow stem cells

    10/01/2007 10:06:45 PM PDT · by Coleus · 6 replies · 94+ views
    There's finally some hope for patients across the globe needing an urgent liver transplant but are unable to find a compatible donor organ. Scientists have, for the first time, found that stem cells, taken from the patients' bone marrow and injected into the diseased liver, can keep them alive until donor organs become available. Miraculously, the cells can also support liver function, until the organ is able to regenerate itself, eliminating the need for a transplant at all. The demand for liver donors is very high and many patients die waiting for one or are taken off because their condition...
  • Stem Cells Offer Hope For The Future Of Plastic Surgery

    08/04/2007 8:36:00 PM PDT · by Coleus · 6 replies · 164+ views
    Spoke Media ^ | OJ Fagbire
    Songtao Shi along with other researchers at the University of Southern California have been conducting experiments utilizing stem cells to grow bone and skin. Shi's newest results could literally change the way cosmetic surgery is performed throughout the world. Shi conducts research in the USC's Center for Craniofacial Molecular Biology. Working together with scientists at dental schools in China and Korea, Shi has discovered that mesenchymal stem cells (MSCs) have the ability to grow bone and tissue as demonstrated in swine and mouse subjects. Although the studies are still in their early stages, the research published in the Stem Cells'...
  • Applauds Stem Cell Clinic for Autism Publication

    08/03/2007 5:55:35 PM PDT · by Coleus · 79+ views (, an organization dedicated to dissemination of stem cell patent information, congratulates the Institute of Cellular Medicine ( for publishing the first peer reviewed paper describing a novel approach for utilizing stem cell therapy for the treatment of autism.  “The published proposal to leverage mesenchymal stem cells to ameliorate the intestinal inflammatory state found in the majority of autistic children, combined with administration of ex vivo expanded CD34 cells for overcoming hypoperfusion in various areas of the brain is of great interest to the stem cell community,“ said Dr. Zhaohui Zhong, Chairman of The paper entitled “Stem Cell...
  • Adult Stem Cells Rebuild Alabama Woman's Heart

    08/03/2007 5:20:41 PM PDT · by Coleus · 6 replies · 482+ views
    CitizenLink ^ | Jennifer Mesko
    Noncontroversial research wins another convert. Alabama event planner Carron Morrow was hanging Japanese lanterns for a wedding last summer when she suffered her fourth heart attack. A week later, the doctor told the 58-year-old mother of two she was a walking time bomb: The right side of her heart was functioning at less than 50 percent. They tried stents and a defibrillator. Then she was put on the heart transplant list.   "All I could do was cry," she says. "I just thought, 'I'm about to die.' There's 100,000 people waiting for a heart."  By fall, she grew worse.  "I...
  • Developments in tissue engineering offer new sources for stem cell treatments

    05/23/2007 7:39:22 PM PDT · by Coleus · 100+ views
    EurekAlert ^ | 05.21.07 | Wendy Isett
    ANAHEIM, Ca. (May 21, 2007) -- Tissue engineering and regenerative medicine offer future patients greater options for treatment and cure of a wide array of urologic conditions, and controversies surrounding the sources of stem cells as well as their use have fueled increased research. Developers from around the world are researching new sources and applications of stem cells. A special session for media highlighting this research was held on May 21 at 9:00 a.m. PDT and was moderated by Roger R. Dmochowski, M.D. ISOLATION OF HUMAN SPERMATOGONIAL STEM CELLS FROM TESTICULAR PARENCHYMA AND DIFFERENTIATION TOWARDS DIFFERENT TISSUES OF THE THREE...
  • Heart science on edge of breakthrough

    05/23/2007 7:34:12 PM PDT · by Coleus · 160+ views
    ABC ^ | 05.22.07 | Jane Cowan
    TONY EASTLEY: If you're over 65, chances are you or your spouse has coronary artery disease. One in two older Australians have the condition and heart disease is still the number one cause of premature death and disability in this country. Scientists have already managed to create heart tissue that beats, and they believe stem cells could be the missing piece of a puzzle that will finally allow them to make a new heart muscle from a person's own tissue. Jane Cowan reports. JANE COWAN: One of the things that makes heart disease so difficult to treat is that heart...
  • Bone marrow stem cells differentiated, produced keratocan in mouse study

    05/23/2007 7:16:24 PM PDT · by Coleus · 155+ views
    OSN ^ | 05.23.07
    Stem cells derived from bone marrow and intrastromally injected into the corneas of mice can differentiate into keratocan-producing cells, according to an experimental study by researchers at the University of Cincinnati. Winston Whei-Yang Kao, PhD, and colleagues investigated whether bone marrow stem cells could differentiate into cells that expressed keratocan, a characteristic of corneal keratocytes. The study involved Kera-/- mice. Hongshan Liu, PhD, a research scientist in the university's ophthalmology department, presented their findings at the Association for Research in Vision and Ophthalmology meeting. The researchers found that, after 1 week, the abnormal corneas of animals injected with the stem...
  • Cord Blood Registry® Releases a Number of Stem Cell Samples to Treat Many Medical Conditions

    05/10/2007 7:14:42 PM PDT · by Coleus · 3 replies · 252+ views
    Businesswire ^ | 04.30.07
    Cord Blood Registry® (CBR®), the world’s largest and most experienced cord blood stem cell bank, today announced that it has released a total of five stem cell samples in the first quarter of the year for transplant or infusion. Three of the cases are individuals who will require their own cord blood stem cells for autologous infusions for cerebral palsy, type I diabetes, and a rare autoimmune disorder related to autism. The additional two samples were released for use by a sibling in each family: one to treat acute myeloid leukemia and the other to treat a serious blood disease,...
  • Adult stem repair of damaged brain, pancreas, kidney cells newly understood

    05/10/2007 7:04:04 PM PDT · by Coleus · 6 replies · 347+ views
    Huliq ^ | 04.30.07
    New studies in the laboratory of Dr. Darwin J. Prockop, Director of Tulane University’s Center for Gene Therapy, are shedding light on the previously mysterious mechanism through which even relatively small amounts of stem/progenitor cells taken from a patient’s own bone marrow enhance repair of damaged tissues. The cells not only differentiate to replace injured cells, as had been understood, but they also stimulate the proliferation and differentiation of stem cells already present in the injured tissue and they transfer mitochondrial DNA to local cells in which the mitochondria (the energy of the cell) is not working. Better understanding of...
  • New gene discovered in human stem cells may benefit transplant patients

    05/10/2007 7:00:25 PM PDT · by Coleus · 1 replies · 158+ views
    News Medical ^ | 04.29.07
    Oxford scientists have revealed a link between a gene and the activity of human blood stem cells, giving hope that stem cell transplant success for blood cancer patients may be significantly improved. Dr Rajeev Gupta, a Leukaemia Research-funded consultant haematologist, has uncovered that the gene Nephroblastoma Overexpressed ( Nov ) plays a key role in regulating the production of blood from stem cells. The work, which was carried out in the MRC Molecular Haematology Unit, is published in the journal Science. Stem cells are vital for normal blood production and are used in transplants in patients with leukaemia and other...
  • Study explores stem-progenitor cells

    05/10/2007 6:53:25 PM PDT · by Coleus · 1 replies · 152+ views
    Science Daily ^ | 05.01.07
    NEW ORLEANS, May 1 (UPI) -- A U.S. study has partly resolved the mystery of how small amounts of adult stem/progenitor cells can repair damaged brain, pancreas, and kidney cells. The researchers in the laboratory of Darwin Prockop, director of Tulane University's Center for Gene Therapy, found the cells not only differentiate to replace injured cells, but also stimulate the proliferation and differentiation of stem cells already present in the injured tissue. Prockop said a better understanding of the different mechanisms of the stem/progenitor cells suggests multiple strategies for developing new therapies for a broad range of diseases, as well...
  • Surgeons Hail Bone Stem Cell Breakthrough

    05/10/2007 6:33:54 PM PDT · by Coleus · 2 replies · 154+ views
    Sky News ^ | 05.05.07 | Thomas Moore
    Surgeons are using stem cells to fix broken bones that won't mend on their own, Sky News has learned. Patients who faced a life of disability or even an amputation because of serious fractures have been able to walk once more. Fifteen patients have so-far been treated in a ground-breaking clinical trial at the Robert Jones and Agnes Hunt Orthopaedic Hospital in Oswestry. Assessments of the first 10 patients show that 8 have been successfully healed. They are able to drive and return to work. Previous attempts to rejoin the bones using metal pins and plates had all failed. Consultant...
  • Celling the Elixir of life

    05/10/2007 6:30:23 PM PDT · by Coleus · 7 replies · 279+ views
    Business Standard ^ | 05.06.07 | Radhieka Pandeya
    Stem Cell therapy is being touted as the answer to many chronic ailments. But even as research is being done, many are already benefitting from it. In the small town of Nagasamudra, just a few miles away from Jog Falls in Karnataka, S B Ramesh, all of 28 years, had built a home with his wife, son and a cable operating business, and dreamt of a fast-paced expansion of his business. Instead, what followed was a nightmare that left him bedridden, numb and disheartened. Today, as he tells me his story over the phone, he expresses the joy he feels...
  • I have been sentenced to death by my sister

    03/26/2007 3:27:31 PM PDT · by paltz · 455 replies · 8,015+ views
    dailymail ^ | 24th March 2007 | By LAURA ROBERTS
    A cancer victim has accused his sister of condemning him to death by refusing to donate her bone marrow for a life-saving operation. Father-of-three Simon Pretty is likely to die from leukaemia within months unless he receives a transplant. His sister Helen, 43, is a perfect match but he says she has turned down the chance to save his life. Without the donation Mr Pretty – who has a rare tissue type – could be dead by the end of the year leaving his wife Jacqueline to raise their children Rebecca, eight, Jack, six and Benjamin, three. he human resources...
  • U of MN adult stem cell research shows promise for transplant therapies

    03/03/2007 6:36:22 PM PST · by Coleus · 132+ views
    EurekAlert ^ | 01.15.07 | Sara E. Buss
    University of Minnesota stem cell researchers, together with collaborators at Stanford University, have successfully used adult stem cells to replace the immune system and bone marrow of mice, offering the promise of new therapies for people in the future. With this advance and other recent discoveries, the researchers are winning over previous skeptics.   For decades, researchers have tried in the lab to expand hematopoietic stem cells (cells that give rise to the blood system). Success in this venture would mean increasing the supply of cells available for bone marrow transplant patients. The researchers used multipotent adult progenitor cells (MAPCs), which...
  • Healing Bone with Stem Cells

    03/08/2007 6:53:15 PM PST · by Coleus · 3 replies · 192+ views
    New techniques to boost survival of adult stem cells could improve surgeries for severe fractures. Implantable materials that grab stem cells and spur their growth and survival could improve bone-healing surgeries. Linda Griffith and her colleagues at MIT have created a new tissue-engineering material that could help cells survive the harsh transplant environment--a key step in cell-transplant therapies. Scientists are now testing the material in animals to see how well it can help heal fractures.  "Creating instructional biomaterials like this is an entirely new way of thinking about what could be put in the human body," says Richard Lee, a...
  • Treating male infertility with stem cells

    03/04/2007 3:20:14 PM PST · by Coleus · 2 replies · 176+ views ^ | 03.02.07
    New research has examined the usefulness of bone marrow stem cells for treating male infertility, with promising results. The related report by Lue et al, “Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure,” appears in the March issue of The American Journal of Pathology. When a couple experiences infertility, the man is just as likely as the woman to be the cause. Male infertility may arise from failed proliferation and differentiation of the germ cells (precursors of sperm) or from dysfunction of the supporting cells. New research is looking to stem...
  • Renal patients’ hope may ‘stem’ from here

    03/04/2007 3:16:52 PM PST · by Coleus · 192+ views
    Indian Express ^ | 03.03.07
    Ahmedabad, March 3: THE illusive grafting of stem cells for kidney transplantation to ensure complete withdrawal of drugs for patients who have undergone this critical transplantation has finally been reached by a team led by Dr HL Trivedi at the Institute of Kidney Diseases and Research Centre (IKDRC). The team infused new kind of stem cells called “Mesenchymal Stem Cells” on one Hetal Mewada who underwent transplantation at the institute on February 9 last. “These cells are infused to create tolerance in the recipient’s body for the donor’s organ,” said Dr Trivedi, Director of IKDRC. Transplanters across the globe have...
  • Aggressive stem cells might improve transplant outcome

    03/03/2007 7:18:21 PM PST · by Coleus · 1 replies · 168+ views
    EurekAlert ^ | 12.07.06 | Bonnie Kourvelas
    St. Jude researchers find that harvesting aggressive stem cells from donated bone marrow could speed rebuilding of the immune system, reduce risk of infection Raymond Barfield, M.D., Ph.D., Division of Bone Marrow Transplantation at St. Jude Children's Research Hospital Click here for more information. Investigators at St. Jude Children's Research Hospital have demonstrated in mice a way that might reduce the time it takes for a bone marrow transplant to rebuild a child's immune system, and so reduce the risk of potentially fatal virus infections that can occur during this time. The St. Jude team showed that the current way...
  • Stem cells cultured from human bone marrow behave like those derived from brain tissue

    03/03/2007 6:32:13 PM PST · by Coleus · 110+ views
    EurekAlert ^ | 01.25.07 | Sandy Van
    Stem cells taken from adult human bone marrow have been manipulated by scientists at the Maxine Dunitz Neurosurgical Institute at Cedars-Sinai Medical Center to generate aggregates of cells called spheres that are similar to those derived from neural stem cells of the brain. In addition, the bone marrow-derived stem cells, which could be differentiated into neurons and other cells making up the central nervous system, spread far and wide and behaved like neural stem cells when transplanted into the brain tissue of chicken embryos. Results of the experiments, described in the February 2007 of the Journal of Neuroscience Research, support...
  • Study: Bone Marrow Stem Cells May be Successful in Treating Parkinson's and MS

    05/02/2006 4:38:17 PM PDT · by wagglebee · 20 replies · 586+ views
    LifeSiteNews ^ | 5/2/06 | LifeSiteNews
    NEW ROCHELLE, N.Y., May 2, 2006 ( - The results of a study published in the April issue of Stem Cells and Development suggest that human stem cells derived from bone marrow are predisposed to develop into a variety of nerve cell types, supporting the promise of developing stem cell-based therapies to treat neurodegenerative disorders such as Parkinson's disease and multiple sclerosis. Stem Cells and Development, a peer-reviewed journal published by Mary Ann Liebert, Inc., carries the paper, entitled "Human Mesenchymal Stem Cells Express Neural Genes, Suggesting a Neural Predisposition." (online here surprising results lend a new perspective...
  • Mesenchymal Stem Cells Show Promise for Severe Graft Versus Host Disease: Presented at ASH

    12/17/2006 10:12:07 PM PST · by Coleus · 29 replies · 514+ views
    Doctor's Guide ^ | 12.14.06
    Stem cell therapy with bone-marrow derived mesenchymal stem cells appears promising to treat graft versus host disease (GvHD), researchers said at the 48th annual meeting of the American Society of Hematology (ASH). Katarina Le Blanc, MD, PhD, Karolinska University Hospital, Huddinge, Stockholm, Sweden, and colleagues transfused mesenchymal stem cells into the gut and liver of a small boy with severe, refractory, life-threatening GvHD as a "last resort" treatment. To their delight, the researchers saw a "remarkable" anti-inflammatory and immunomodulatory response, Dr. Le Blank said in a presentation on December 12th. It has been known for some time that bone marrow...
  • Aldagen To Launch Clinical Trial Using ADULT Stem Cells To Combat Disease In Arms, Legs

    12/17/2006 9:13:17 PM PST · by Coleus · 3 replies · 350+ views ^ | 12.15.06
    Aldagen, a company focused on stem cell research, and the Texas Heart Institute are teaming up for a clinical trial in which humans will be tested for a potential treatment of limb ailments brought on by blood vessel problems. The treatment is based on the use of purified adult stem cells drawn from bone marrow. The Food and Drug Administration approved the launch of the Phase II trial earlier this year. The stem cells are prepared for use by Aldagen’s proprietary technology known as Aldesort. The National Institutes of Health has said stem cells have the "remarkable potential" to develop...
  • Stem cell trial may bring end of back pain for millions

    11/30/2006 7:57:54 AM PST · by Mrs Ivan · 18 replies · 1,028+ views
    The Daily Mail ^ | 30th November 2006
    A radical new treatment could bring relief to millions of back pain sufferers, scientists said today. A team at the University of Manchester has developed a stem cell cure that could totally regenerate damaged tissues. Low back pain affects up to 80 per cent of the population at some point, and in many cases becomes persistent, eventually leading to debilitating pain. It is usually caused by the degeneration of the tissue between the discs in the back, which becomes dry and no longer able to support the body. Current treatments rely on strong painkillers or risky surgery, and aim to...
  • Stem cell cure hope for diabetes

    11/11/2006 11:04:13 PM PST · by batter · 51 replies · 1,216+ views
    BBC ^ | 12 November 2006 | BBC
    Scientists have used stem cells from human bone marrow to repair defective insulin-producing pancreatic cells responsible for diabetes in mice. The treatment also halted damage to the kidneys caused by the condition. Researchers from New Orleans' Tulane University are hopeful it can be adapted to treat diabetes in humans. The study, featured in Proceedings of the National Academy of Sciences, was welcomed as "interesting work" by Diabetes UK. Stem cells are immature cells which have the capacity to turn into any kind of tissue in the body. The US team treated diabetic mice who had high blood sugar and damaged...
  • Stretching bone marrow stem cells pushes them towards becoming blood vessel

    10/23/2006 9:30:26 PM PDT · by Coleus · 5 replies · 307+ views
    EurekAlert ^ | Sarah Yang | 10.23.06
    Mesenchymal stem cells can be grown on silicone membranes with micropatterned grooves. These grooves can align the cells with the direction of stretch in a specialized "stretch chamber." Click here for more information. Berkeley -- When stretched, a type of adult stem cell taken from bone marrow can be nudged towards becoming the type of tissue found in blood vessels, according to a new study by bioengineers at the University of California, Berkeley.  Researchers placed mesenchymal stem cells onto a silicone membrane that was stretched longitudinally once every second. It was a cellular workout routine that helped point the...

    09/21/2006 7:57:55 PM PDT · by Coleus · 4 replies · 428+ views
    Mercury News ^ | 09.21.06 | Karen Kaplan and Alan Zarembo
    Using stem cells harvested from patients' own bone marrow, researchers reported Wednesday that they improved cardiac function in heart attack patients months, years -- and even decades -- after the patients suffered their attacks. The infusion of stem cells boosted cardiac pumping efficiency by 7 percent in three months -- a modest gain, but still an improvement for a chronic condition. In one case, a patient who had suffered a heart attack 30 years earlier showed an 11 percent improvement after the treatment, according to the study published in the New England Journal of Medicine. The German researchers also found...
  • Stem cells: Chemistry paves way toward promising therapies

    09/14/2006 9:58:32 AM PDT · by Coleus · 4 replies · 244+ views
    EurekAlert ^ | 09.10.06 | Michael Bernstein
    Chemists are developing new insights and techniques in an effort to expand the therapeutic potential of stem cells, which includes possible treatments for Parkinson's disease, diabetes, spinal cord injury and other devastating conditions. The American Chemical Society will explore some of these latest developments, including new findings on the transformation potential of adult stem cells, during a special symposium, "Emerging Technologies: Stem Cells," on Thursday, Sept. 14, in San Francisco during the Society's 232nd national meeting. All papers in this symposium, which begins at 1:30 p.m., will be presented at the Hilton San Francisco, Yosemite B. Shown below are selected...
  • Administering Stem Cells To Patients With Myocardial Infarction Leads To Reduction Of The Infarct

    01/16/2006 2:07:09 PM PST · by Founding Father · 15 replies · 584+ views
    Science Daily ^ | January 16, 2006
    Administering Stem Cells To Patients With Myocardial Infarction Leads To A Reduction Of The Infarct Doctors at the Catholic University of Leuven, connected with the University Hospital - Gasthuisberg, the Stem Cell Institute Leuven (SCIL), and the Flanders Interuniversity Institute for Biotechnology (VIB), recently publishing a major breakthrough in the treatment of patients with acute myocardial infarction. Their research shows that the administration of a patient's own stem cells has a significant positive effect on the heart's recovery: in the patients studied, the size of the infarct was clearly reduced. The use of stem cells appears to be safe, and...
  • Role of the nervous system in regulating ADULT stem cells discovered

    09/03/2006 10:15:05 PM PDT · by Coleus · 3 replies · 285+ views
    EurekAlert ^ | 01.26.06 | Paul Frenette
    Role of the nervous system in regulating stem cells discoveredStudy led by Mount Sinai School of Medicine may provide new hope for cancer patients and others with compromised immune systems  New study by Mount Sinai researchers may lead to improved stem cell therapies for patients with compromised immune systems due to intensive cancer therapy or autoimmune disease. The study is published in this week's issue of Cell.  A group, led by Paul Frenette, Associate Professor of Medicine at Mount Sinai School of Medicine, found that the sympathetic--or "fight or flight" branch--of the nervous system plays a critical role in coaxing...
  • Cloning the heart (using ADULT Stem Cells)

    09/02/2006 9:19:34 PM PDT · by Coleus · 2 replies · 428+ views
    Existing methods of treatment are not quite effective in repairing damaged heart muscle in end-stage cardiovascular diseases. New research suggests that stem cells can regenerate into heart cells. Nandini Patwardhan traces the significance of stem cells in the cardiovascular segment  It is nothing short of a miracle that a cell, a combination of ova and a sperm, duplicates into a human body in nine months. That is the power of stem cells. This hypothesis has inspired stem cell research in cardiology in India.  Simply put, stem cells are the most basic cells in the human body. They are those unspecialised...
  • Catholic Priest's Adult Stem Cell Donation Saves Kentucky Woman's Life

    09/02/2006 8:05:18 PM PDT · by Coleus · 6 replies · 409+ views
    Life News ^ | 06.29.06 | Steven Ertelt
    Kansas City, MO ( -- A Catholic priest from Kansas City who donated his adult stem cells to save a Kentucky woman's life surprised her at a local pro-life event by showing up to offer his encouragement and support. Lee Ann Collins, a mother of two from Kentucky, had no idea Father Ken Riley would fly to the event to greet her. Collins didn't know Father Riley, pastor at St. Bernadette Parish in Kansas City, three years ago when doctors were looking for stem cell donors to help treat her leukemia. Father Riley was a potential match and he had...