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Researchers conducted a phase I pilot study to assess the feasibility of using potato starch as a dietary intervention to modify the gut microbiome in bone marrow transplant patients. The study is the first part of a two-phase ongoing clinical trial evaluating the effect of modifying the microbiome on the incidence of graft-versus-host disease (GVHD), a major complication that develops in up to half the patients who receive a bone marrow transplant and can lead to injury and death. Previous pre-clinical data from the Reddy lab demonstrated that butyrate, a compound produced by healthy intestinal bacteria when they digest resistant...

Anew cancer therapy developed at Jerusalem’s Hadassah-University Medical Center had a 90% response rate in a new clinical trial, with over half of patients going into total remission. The CAR-T therapy — which arms the body’s own immune cells to fight cancer — was able to send multiple myeloma, an extremely deadly cancer that impacts the immune system, into remission. The therapy is the result of years worth of experiments conducted by the hospital’s bone-marrow transplant and immunotherapy department, the Jerusalem Post reported. “We have evidence of a very positive overall response rate with minimal side effects, and they are...

Rejuvenating an older person's blood may now be within reach, based on recent findings. An anti-inflammatory drug, already approved for use in rheumatoid arthritis, can turn back time in mice and reverse some of the effects of age on the hematopoietic system. "These results indicate that such strategies hold promise for maintaining healthier blood production in the elderly," Mitchell says. The researchers only identified the drug after a comprehensive investigation of the stem cells that create all blood cells and the niches where they reside in the center of the bones. Mitchell took a closer look at the stem cells'...

Applying regenerative medicine to a common shoulder surgery could have an impact on the need for follow-up revision surgery in some patients, according to a study. The analysis identified patients who had a regenerative intervention added to augment rotator cuff repair surgery. The data indicated that patients who opted for bone marrow aspirate concentrate at the time of surgery were less likely to need a second surgery. "The data we analyzed suggested a nearly threefold reduction in revision surgery in patients who received bone marrow aspirate concentrate, compared to those who did not," says Bradley Schoch, M.D. Regenerative medicine is...

Disintegrating Virus Cell Destroy COVID Concept The injection causes type B white blood cells to be genetically engineered inside the patient’s body that would generate neutralizing antibodies against the HIV virus. The technology also has the potential to be developed into a cure for AIDS Adi Barzel Lead author of the study, Dr. Adi Barzel. Credit: Tel Aviv University A new study from Tel Aviv University proposes a novel AIDS treatment that could be turned into a vaccine or a one-time treatment for HIV patients. The research explored modifying type B white blood cells in the patient’s body to release...

We recently heard about Ella and were told to be waiting for a universal notice for help. Apparently a match is difficult to find

Stone artifacts painstakingly shaped into spheres were part of the daily lives of early humans for more than two million years. They have been unearthed by archaeologists in East Africa, humanity's ancestral home, and they litter prehistoric sites across Eurasia from the Middle East to China and India. Yet experts have been puzzled by their function since the early days of research into our evolutionary history. Now, an international team of archaeologists led by Tel Aviv University archaeologist researcher Ella Assaf, has produced evidence that these enigmatic artifacts were used for a very specific purpose: breaking the bones of large...

After a bone marrow transplant, a man with leukemia found that his donor’s DNA traveled to unexpected parts of his body. A crime lab is now studying the case. Three months after his bone marrow transplant, Chris Long of Reno, Nev., learned that the DNA in his blood had changed. It had all been replaced by the DNA of his donor, a German man he had exchanged just a handful of messages with. He’d been encouraged to test his blood by a colleague at the Sheriff’s Office, where he worked. She had an inkling this might happen. It’s the goal...

Tel Aviv University researchers, in collaboration with scholars from Spain, have uncovered evidence of the storage and delayed consumption of animal bone marrow at Qesem Cave near Tel Aviv, the site of many major discoveries from the late Lower Paleolithic period some 400,000 years ago. The research provides direct evidence that early Paleolithic people saved animal bones for up to nine weeks before feasting on them inside Qesem Cave... The researchers contend that the deer metapodials were kept at the cave covered in skin to facilitate the preservation of marrow for consumption in time of need. The researchers evaluated the...

Shortly before undergoing surgery so that he could donate bone marrow to a 14-year-old boy in France, Derrick Nelson, a high school principal in Westfield, N.J., granted an interview to a student journalist. “If it’s just a little bit of pain for a little bit of time that can give someone years of joy,” he told her, “it’s all worth it.” In October, an organization that connects people suffering from life-threatening diseases with potential bone marrow donors had contacted the principal after he showed up as a potential match for the French patient. When follow-up testing confirmed the match, the...

Click on the red link under the title. Have tissue ready. This will be 2 minutes and 2 seconds of joy.

She said she was disheartened when she turned to a worldwide registry of donors and none were compatible. "It was 30 million people," she said. "Thirty million people, and no matches for me." So Rabaca and the rest of her family partnered with Be The Match, an organization operated by the National Marrow Donor Program, to encourage people to register to donate bone marrow. Thanks to their fierce campaigning, Rabaca's story spread and gained attention from the likes of country singer Carrie Underwood, who asked her Twitter followers, "who wants to save a life for Christmas?" In a matter of...

Doctors have treated only three leukemia patients, but the sensational results from a single shot could be one of the most significant advances in cancer research in decades. And it almost never happened. In the research published Wednesday, doctors at the University of Pennsylvania say the treatment made the most common type of leukemia completely disappear in two of the patients and reduced it by 70 percent in the third. In each of the patients as much as five pounds of cancerous tissue completely melted away in a few weeks, and a year later it is still gone

A good athlete is often called on to save a game. This is the story of a star football player who was asked to save a life of someone he didn't even know. CBS News correspondent Wyatt Andrews has the latest example of "The American Spirit." There were four finalists last night for the Gagliardi Trophy, basically the Heisman for Division III college football. But for finalist Matt Hoffman learning if he'd win wasn't the suspense of the night.  Meeting cancer patient Warren Sallach was.  Last year Matt donated his bone stem cells - in an anonymous donation that went...

Scrambling to get 60 seconds out of every minute, Katie Meacham finally got the boyfriend to take her for a carriage ride in Central Park. He hated it, she reports. “He said, ‘You know this is a pity ride, don’t you?’ ” she said, laughing. Even though she is just 26, her days and time are at a premium. Ms. Meacham lives on the Upper East Side of Manhattan, but she is also a citizen of another country: cancer land. She has a kind of aggressive lymphoma, a disease that ruins the blood.

"HAYWARD, Calif. – If Nick Glasgow were white, he would have a nearly 90 percent chance of finding a matching bone marrow donor who could cure his leukemia. But because the 28-year-old bodybuilder is one-quarter Japanese, his doctor warned him the outlook was grim. Glasgow's background would make it almost impossible to find a match, which usually comes from a patient's own ethnic group. The doctor "didn't say it was slim-to-none. He didn't say it would be hard. He said 'zero chance,'" Glasgow's mother, Carole Wiegand, recalled with tears in her eyes. "When Nick heard that, it sent him plummeting."...

Genetically engineered stem cells from bone marrow showed promise as a potential new way to deliver a cancer-killing protein to tumors, British researchers said on Tuesday. Experiments in cell cultures and in mice showed the adult stem cells — a type known as mesenchymal stem cells — could home in on cancer cells and deliver a lethal protein that attacked only the cancer while sparing normal healthy tissue. “We’ve developed cells which specifically target cancer through the body and deliver an anti-cancer protein to where it is needed in a seek-and-destroy approach,” said Dr. Michael Loebinger of University College London,...

CHENNAI: Adult stem cells extracted from the patient’s bone marrow have been found to cure several ailments, but a therapy for regeneration of blood vessles hold out bigger hopes. The department of vascular surgery at the Sri Ramachandra Medical College Hospital and Research Institute in December 2007 has used adult stem cells to trigger growth of new blood vessels in the limbs of at least 30 patients who suffer from critical limb ischemia — a condition of blood vessels in the limb getting blocked, often resulting in amputation. When SRMC doctors told a 64-year-old diabetic patient in December, 2007 that...

Adult Stem Cells Successfully Reset Immune System for Multiple Sclerosis Patients by Steven ErteltLifeNews.com Editor January 29, 2009 Chiacgo, IL (LifeNews.com) -- Adult stem cells continue to outpace their embryonic counterparts by successfully treating patients with a variety of diseases and conditions. Now, the use of adult stem cells from bone marrow has helped patients suffering from the early stages of multiple sclerosis.A new study shows a research team appears to have reversed the neurological dysfunction of early-stage multiple sclerosis patients by transplanting their own immune stem cells into their bodies and thereby "resetting" their immune systems.Dr. Robert Burt,...

A spinal surgeon in Aurora, Colo., recently performed what's being called the first disc surgery in the United States using adult stem cells to help repair a man's injured lower back. "Stem cells have shown great promise over the past three years for treating back pain," Dr. Jeffrey Kleiner said. "In combination with the diskectomy, we hope to offer patients long-term relief from their back pain and to decrease their risk of needing additional surgeries." Adult stem cells have been injected into patients' backs and joints to promote tissue growth, but this is the first time stem cells have been...