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Keyword: extracellularmatrix

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  • Tissue engineering: How to build a heart

    07/04/2013 2:23:05 PM PDT · by neverdem · 6 replies
    Nature News ^ | 03 July 2013 | Brendan Maher
    With thousands of people in need of heart transplants, researchers are trying to grow new organs. Doris Taylor doesn't take it as an insult when people call her Dr Frankenstein. “It was actually one of the bigger compliments I've gotten,” she says — an affirmation that her research is pushing the boundaries of the possible. Given the nature of her work as director of regenerative medicine research at the Texas Heart Institute in Houston, Taylor has to admit that the comparison is apt. She regularly harvests organs such as hearts and lungs from the newly dead, re-engineers them starting from...
  • Researchers Develop Injectable Gel to Repair Damaged Hearts

    02/25/2013 9:31:30 PM PST · by neverdem · 22 replies
    Voice of America ^ | February 21, 2013 | Jessica Berman
    People who suffer heart attacks are at increased risk of having a second and potentially fatal occurrence because of the damage the heart attack does to cardiac muscle tissue. Now scientists at the University of California San Diego have developed a new biomaterial - an injectable hydrogel  - that can repair the damage from heart attacks, and help promote the growth of new heart tissue.   Millions of people around the world suffer heart attacks every year and survive. These traumatic events occur when blood supply to the heart muscles is somehow blocked, robbing them of oxygen and causing them...
  • Stem cell 'sticky spots' recreated by scientists

    12/13/2012 6:51:25 PM PST · by neverdem · 1 replies
    Biology News Net ^ | December 13, 2012 | NA
    Randomly distributed sticky spots which are integral to the development of stem cells by maximising adhesion and acting as internal scaffolding have been artificially recreated by experts from the University of Sheffield for the first time. Using synthetic foam type materials to mimic the natural process – known as the extracellular matrix or ECM – scientists, from the University of Sheffield and University of California San Diego, created the random stickiness required for stem cells to properly adhere. The findings will better inform researchers across the world of how to make their biomaterials appropriately sticky for stem cells to grow....
  • Human Muscle, Regrown on Animal Scaffolding

    09/29/2012 6:45:56 PM PDT · by neverdem · 17 replies
    NY Times ^ | September 16, 2012 | HENRY FOUNTAIN
    In the months after a roadside bomb in Afghanistan blew off part of his left thigh, Sgt. Ron Strang wondered if he would ever be able to walk normally again. The explosion and subsequent rounds of surgery left Sergeant Strang, 28, a Marine, with a huge divot in his upper thigh where the quadriceps muscle had been. He could move the leg backward, but with so much of the muscle gone he could not kick it forward. He could walk, but only awkwardly. “I got really good at falling,” he said of his efforts. And Sergeant Strang... --snip-- “I thought,...
  • Spare Parts for Humans: Tissue Engineers Aim for Lab-Grown Limbs, Lungs and More

    12/19/2011 11:33:46 PM PST · by neverdem · 12 replies
    PBS NewsHour ^ | Dec. 15, 2011 | Miles O'Brien
    A new research breakthrough has enabled scientists to grow human tissue to repair or replace organs, and someday, maybe even limbs. Science correspondent Miles O'Brien reports.Be advised: Some of the images are graphic.MILES O'BRIEN: I am not sure when or why I thought it was a good idea to go for a bike ride on a 100-degree Texas afternoon with a 26-year-old Marine corporal. There I was eating Isaias Hernandez's dirt. No surprise, right? Well, take a look at his right thigh.CPL. ISAIAS HERNANDEZ, U.S. Marine Corps: It looked like a chicken, like if you would take a bite out...