Free Republic

The PandeGroup has all been very excited about the great turnout of FAH donors over the last few weeks, allowing FAH to go over a petaflop. The PS3's have been cranking out some very useful scientific results due to the new scientific software present in v1.2. The PS3's are so fast, we've been looking at the results sometimes 2x to 3x a day (instead of a couple times a month). If all goes well, we're hoping to write up these results soon (maybe a few weeks) for peer reviewed publication. It's also interesting to think about what we want to...

We live in the age of the prion, says New York writer DT Max in his introduction to this neat little medical whodunit. The claim sounds worthy of a car advert. You are never alone with a prion. That sort of thing. In fact, the prion is a strange, non-living infectious agent whose behaviour was widely disputed until US medical researcher Stanley Prusiner confirmed its existence in a series of elegant experiments that won him a Nobel Prize for physiology in 1997. Now, most scientists accept prions are responsible for a range of modern curses: mad cow disease, the fatal...

Time for an update. The Free Republic Folding team #36120 started about 4 years ago, and became popular in December of 2005. We will hit 30,000,000 points this week and congratulations are in order to all folders. Our FreeRepublic team of 475 members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is...

Pharmed food crop approved for growth despite controversy.Rice modified to express proteins often found in breast milk will be planted in Kansas. It's certainly not the first crop designed to produce pharmaceutical proteins given the go-ahead in the United States or elsewhere (see 'Turning plants into protein factories'). But this is among the first food crops containing genes that produce human proteins to gain approval for large-scale planting. Many other pharmaceutical genetically-modified (GM) crops are grown indoors or in inedible plants such as tobacco. The rice strains, made by Ventria Bioscience in Sacramento, California, produce lysozyme, lactoferrin and human serum...

Cardiologists are increasingly using adult stem cells in clinical trials to repair hearts following heart attacks, but no one has understood how the therapy actually works. Now, in animal experiments, researchers at The University of Texas M. D. Anderson Cancer Center have deconstructed the process, describing how the stem cells fuse with heart muscle cells to create new cells that repopulate the ailing organ. In a paper posted at Online First of the journal Circulation Research, investigators found that this fusion is only possible if two cell adhesion proteins that stick to each other like Velcro are available to attach...

NEW YORK: A newly designed porous membrane, so thin that it's invisible edge-on, might revolutionise the way doctors and scientists manipulate objects as small as molecules. The 50-atom thick filter can withstand surprisingly high pressures and may be a key to better separation of blood proteins for dialysis patients, speeding ion exchange in fuel cells and purifying air and water at the nanoscopic level. "It's amazing, we have a material as thin as some of the molecules it's sorting, and riddled with holes - but it can withstand enough pressure to make real-world nano-filtering a practical reality," said Christopher Striemer...

OK, new thread for the next week, celebrating 100,000 Work Units! First, a big shout out to the SETI and BOINC members who have added CPUs to the effort. Remember, its Team 36120, NOT Team 0. Next, congrats to all for bumping our team up to 1040 processors and 420 user names. We now have 29 members who have contributed at least 100,000 points each. Woo-Hoo! Even more impressive, our team now boasts 342 members who have folded at least 1,000 points. That is more than the entire number of folders for our erstwhile left-wing environazi competitors! Free Republic Folding@Home...

Scientists at Duke University Medical Center have visualized in a living animal how cells use a critical biological process to dice and splice genetic material to create unique and varied proteins. The scientists say the findings, made in mice, help explain a key wonder of human biology: how the same genes found in every cell of an individual’s body can produce different proteins in different tissues and organs. These varied proteins, in turn, dictate the function of each tissue or organ. The findings also may offer insight into a number of diseases, including cancer, in which the genetic process --...

Time for a new FreeRepublic folding@home thread. Our FreeRepublic team of 358 members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 75th place (with 1,020 active CPUs - 70,500 completed Work Units and 12.75 million points). This is an entirely voluntary program, and if you want to learn more, please...

Time for a new FreeRepublic folding@home thread. Our FreeRepublic team of 358 members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 75th place (with 1009 active CPUs - 55,700 completed Work Units and 9.75 million points). This is an entirely voluntary program, and if you want to learn more, please...

Time for a new FreeRepublic folding@home thread. Our FreeRepublic team of 351 members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 85th place (with 908 active CPUs - 47,400 completed Work Units and nearly 8.5 million points). This is an entirely voluntary program, and if you want to learn more,...

A computer system that automatically tracks the movements of proteins within a living cell has been developed by a team of biologists and computer vision experts. It could save researchers the hours often spent analysing microscope images by hand, to determine the way a cell works. The system, called CellTracker, automatically analyses a series of still digital images captured through a microscope. Doug Kell at Manchester University in UK, the lead biologist involved with the project, believes the system could dramatically speed up studies of cells' function. "Most people just fix cells [in one place], which kills their metabolism," he...

Time for a new FreeRepublic folding@home thread. Our FreeRepublic team of 342 members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 99th place (with 985 active CPUs - 39,500 completed Work Units and nearly 7 million points). This is an entirely voluntary program, and if you want to learn more,...

Time for a new FreeRepublic folding@home thread. Our FreeRepublic team of 337 members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 103th place (with 988 active CPUs - 36,400 completed Work Units and more than 6,4 million points). This is an entirely voluntary program, and if you want to learn...

Time for a new FreeRepublic folding@home thread. Our FreeRepublic team of 325+ members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 108th place (with 991 active CPUs - 34,150 completed Work Units and more than 6,000,000 points). This is an entirely voluntary program, and if you want to learn more,...

Time for a new FreeRepublic folding@home thread. Our FreeRepublic team of 300+ members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 117th place (with 1,038 active CPUs - 29,000 completed Work Units and more than 5,000,000 points). This is an entirely voluntary program, and if you want to learn more,...

Time for a new FreeRepublic folding@home thread. Our FreeRepublic team of 300+ members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 144th place (with 1,045 CPUs - 24,200 completed Work Units and nearly 4,000,000 points) This is an entirely voluntary program, and if you want to learn more, please see...

Time for a new FreeRepublic folding@home thread. Our FreeRepublic team of 300+ members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 164th place (with 992 CPUs - nearly 19,000 completed Work Units and 2,982,241 points) This is an entirely voluntary program, and if you want to learn more, please see...

Time for a new FreeRepublic folding@home thread. Our FreeRepublic team of 250+ members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 188th place (with 940 CPUs - 15,725 completed Work Units and 2,330,000 points) This is an entirely voluntary program, and if you want to learn more, please see the...

Time for a new FreeRepublic folding@home thread. While this folding@home team is not officially sanctioned by Free Republic, it's 250+ members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 204th place, having reached more than 2,000,000 points! This is an entirely voluntary program, and if you want to learn more,...

Welcome to the new FreeRepublic folding@home thread. The previous thread has gotten too large, so we move on to yet another. While this folding@home team is not officially sanctioned by Free Republic, it's 250+ members comprised primarily of Free Republic members in good standing have banded together to donate their excess CPU cycles to a worthy cause. Via distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimer's, Cancer, and Mad Cow (BSE). Currently, the team is in 241st place, having moved up from 1200th...

Background Cancer is a major medical problem in modern societies. However, the incidence of this disease in non-human primates is very low. To study whether genetic differences between human and chimpanzee could contribute to their distinct cancer susceptibility, we have examined in the chimpanzee genome the orthologous genes of a set of 333 human cancer genes. Results This analysis has revealed that all examined human cancer genes are present in chimpanzee, contain intact open reading frames and show a high degree of conservation between both species. However, detailed analysis of this set of genes has shown some differences in genes...

Welcome to the folding at home thread. The previous thread has gotten too large, so we move on to yet another. While this folding@home team is not officially sanctioned by Free Republic, it's members, or it's founders, it is comprised primarily of Free Republic members in good standing, who have banded together, to donate their excess CPU cycles to a worthy cause. Via Distributed computing, millions of computers around the world, contribute directly to scientific research, in the quest for a greater understanding of diseases such as Alzheimers, Cancer, and Mad Cow (BSE). Currently, the team is in 777th place,...

New thread for this week. Congrats to all new members who joined this week! We've made excellent progress so far and have smoked the DUmmies and Kossacks. Let's keep folding!

A continuation of the Freeper Folder Thread

OK, new thread to celebrate reaching a major milestone! Within a few hours Team FreeRepublic will be in the Top1000!!!! We should pass Dean for America, around noon tommorrow. Other liberal teams want to challenge us (DUmmies and Kos) but we're humiliating them beyond description.

OK, new thread for the next week. First, a big shout out to the SETI members who have added CPUs to the effort. Remember, its Team 36120, NOT Team 0. Next, congrats to all for bumping our team up to 104 processors and 76 users. We have a number of new users in the team, with Clara Lou, fzx12345, SamfromLivingston, brityank, manwiththehands and Tami all popping onto the hit list this week. Malsua, uriah and Ken in Texas are solidly in the top 10. Malsua is continuing to add systems and now accounts for 10% of the FR total. Great...

OK, new thread for the next week. First, a big shout out to the SETI members who have added CPUs to the effort. Remember, its Team 36120, NOT Team 0. Next, congrats to all for bumping our team up to 65 processors. ArgentCent is the latest to have joined our happy band of folders and jumps in at # 36 with his first completed WU. We now have 51 members in the team, and about 45 active participants. Malsua, uriah and Ken in Texas are solidly in the top 10. One of these will probably be the new Numero Uno...

FreeRepublic Team Ranked #1,550 (of 41,708 teams)

FR Team ranking up to number 1782 of 41608

Folding@Home update: 3 Work Units completed, 2 computers, 138 points, overall team rank #15,162

Any Freepers "folding@home"???? For those not familiar with F@H -> some diseases such as cancer, Alzheimer and even "mad cow" disease are believed to be linked to protein (mis)folding. A scientist team from Stanford University studies this phenomenon to try and find a cure to these diseases. To do this, they have designed a software (folding@home) which enables people to donate unused power from their computer to speed up medical research!

Charles Darwin, the 19th century geologist who wrote the treatise 'The Origin of Species, by means of Natural Selection' defined evolution as "descent with modification". Darwin hypothesized that all forms of life descended from a common ancestor, branching out over time into various unique life forms, due primarily to a process called natural selection. However, the fossil record shows that all of the major animal groups (phyla) appeared fully formed about 540 million years ago, and virtually no transitional life forms have been discovered which suggest that they evolved from earlier forms. This sudden eruption of multiple, complex organisms is...

By examining how proteins have evolved, UT Southwestern Medical Center researchers have discovered a set of simple "rules" that nature appears to use to design proteins, rules the scientists have now employed to create artificial proteins that look and function just like their natural counterparts. In two papers appearing in the Sept. 22 issue of the journal Nature, Dr. Rama Ranganathan, associate professor of pharmacology, and his colleagues detail a new method for creating artificial proteins based only on information they derived from analyzing certain characteristics that individual natural proteins have in common with each other. "The goal of our...

SYDNEY (AFP) - Australian scientists have discovered pineapple molecules can act as powerful anti-cancer agents and said the research could lead to a new class of cancer-fighting drugs. Scientists at the Queensland Institute of Medical Research (QIMR) said their work centred on two molecules from bromelaine, an extract derived from crushed pineapple stems that is used to tenderise meat, clarify beers and tan hides. One of the molecules, CCZ, stimulates the body's immune system to target and kill cancer cells, the other, CCS, blocks a protein called Ras, which is defective in 30 percent of all cancers. QIMR researcher Tracey...

New research into primitive protective proteins from the immune systems of sharks could lead to more versatile drugs to battle diseases such as cancer and dangerous bacterial infections and to robust diagnostic kits that could easily leave the lab, an area of intense research following the anthrax attacks of 2001. In a study published Thursday online by the journal Science, researchers at The Scripps Institute in La Jolla, CA, and the University of Maryland at Baltimore determined that the structure of the primitive antibody that marks a difference between the immune systems of sharks and mammals is unusually simple. Ian...

Scientists are reporting that, for the first time, they have made an artificial prion, or misfolded protein, that can, by itself, produce a deadly infectious disease in mice and may help explain the roots of mad cow disease. The findings, being reported on Friday in the journal Science, are strong evidence for the so-called "protein only hypothesis," the controversial idea that a protein, acting alone without the help of DNA or RNA, can cause certain kinds of infectious diseases. The concept was introduced in 1982 by Dr. Stanley Prusiner, a neurology professor at the University of California in San Francisco,...

n an advance that could lead to three-dimensional pictures of proteins and other molecules, scientists have developed a magnetic resonance imaging technique that can detect a single electron. "There's lots of things this will be useful for," said Dr. Daniel Rugar, manager of nanoscale studies at I.B.M.'s Almaden Research Center in San Jose, Calif., and leader of the research team, which is reporting the findings today in the journal Nature. "There are thousands of proteins in the body whose structures are not known." It is largely proteins' shapes that enable them to carry out the essential functions of the body,...

Herbal alternatives are under attack. Download and print flyers. The flyers urge consumers to tell their congressmen and senators to attend the JUNE 17th Herbal Alternatives Congressional Briefing to learn the truth about herbs & health. It is critical that Congress attends this briefing because: HERBAL ALTERNATIVES ARE UNDER ATTACK. News headlines misinform and mislead decision makers. Products you depend on for your health could soon be banned. MANY CAPITOL HILL STAFFERS AND POLICY MAKERS DO NOT UNDERSTAND NATURAL HEALTH INDUSTRY ISSUES. Since DSHEA was passed in 1994, about 50% of Congressmen and Senators and 80% of Congressional aides have...

Scientists have discovered that monkey cells have innate protection against infection with the human AIDS virus, a clue that may help explain why some people are susceptible to certain viral infections while others are not. The finding, reported in today's issue of the journal Nature, offers one of the first concrete examples of what researchers call an intracellular system of innate immunity and may open the door to the development of new antiviral therapies, the scientists said. The monkeys were protected from the virus by a mechanism that resides within cells and that is independent of the antibodies and white...

NASA nanometer breakthrough uses hot pond protein You couldn't make it up By Paul Hales: Wednesday 27 November 2002, 11:35 NASA SCIENTISTS say they have invented a breakthrough biological method to make ultra-small structures that could be used to produce electronics 10 to 100 times smaller than today’s components. The scientists apparently use modified proteins from 'extremophile' microbes to grow mesh-like structures so small that an electron microscope is needed to see them. These naturally-occurring microbes live in near-boiling, acidic hot springs, according to an article in on-line version of the journal Nature Materials. One of the scientists, Andrew McMillan,...

New word in life's lexiconResearchers find 22nd amino acid in a microbe.24 May 2002JOHN WHITFIELDThere's a new word to life's vocabulary. DNA letters can be rearranged to spell out a 22nd amino acid, researchers have discovered. DNA: the letters of life have more permutations than we thought. © Getty Images The scientists who cracked life's genetic code in the 1950s said that it writes a mere 20 'words' - the amino acids from which the myriad proteins in all life are built. But in 1986 another amino acid was discovered in bacteria. "We thought the 21st was an aberration,...