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Simple molecule could prevent, alleviate pre-diabetes
ScienceDaily ^ | February 7, 2018 | University of Sydney

Posted on 06/24/2018 6:59:46 AM PDT by ConservativeMind

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There is an expensive form of CoQ10 called, “MitoQ.” It does directly migrate into the mitochondria 700-1000 times more than normal CoQ10.
1 posted on 06/24/2018 6:59:46 AM PDT by ConservativeMind
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To: ConservativeMind

Why can’t these people just lose some weight? Sen. Tom Colburn said diabetes was 50% preventable. An ounce of prevention... BTW diabetes runs in my family. 2-3 had type 1. Those folks are real screwed.


2 posted on 06/24/2018 7:03:25 AM PDT by DIRTYSECRET (urope. Why do they put up with this.)
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To: ConservativeMind

I take Lipitor. My doctor has never said anything about CoQ10. I’ve red I should be taking it. I am also type 2. Is this MitoQ safe?


3 posted on 06/24/2018 7:05:41 AM PDT by boycott
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To: ConservativeMind

ConservativeMind wrote:

“There is an expensive form of CoQ10 called, “MitoQ.” It does directly migrate into the mitochondria 700-1000 times more than normal CoQ10.”

Many thanks for posting the article and this info!

Here’s some info about it that I found:

https://www.selfhacked.com/blog/mitoq/


4 posted on 06/24/2018 7:09:52 AM PDT by WildHighlander57 ((WildHighlander57, returning after lurking since 2000)
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To: DIRTYSECRET

Doesn’t insulin resistance make it difficult for people to lose weight?


5 posted on 06/24/2018 7:12:03 AM PDT by WildHighlander57 ((WildHighlander57, returning after lurking since 2000)
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To: boycott

I took Lipitor at one time. I think it caused my foot neuropathy.


6 posted on 06/24/2018 7:29:22 AM PDT by 353FMG
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To: boycott
Yes, it is safe. However, to let it go “further” in your body, consider taking CoQ10 or the better, converted form, ubiquinol, with it. A Jarrow version is available on Amazon 120 capsules (4 month supply of 100 mg daily) for about $35, but a three month supply for one person of MitoQ is $169.

There is a ubiquinol at Costco that doesn’t require eating with fat, but it works because of about 100 mg of Polysorbate 80 is there as an emulsifier. People can develop allergies to Polysorbate 80.

My wife and I started taking MitoQ three weeks ago to test it out.

7 posted on 06/24/2018 7:31:41 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Thanks. I’ll check into it.


8 posted on 06/24/2018 7:35:32 AM PDT by boycott
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To: ConservativeMind

Does anyone know about the benefits of alpha lipoic acid? It is used in Europe to treat diabetes.


9 posted on 06/24/2018 7:43:02 AM PDT by 353FMG
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To: ConservativeMind

>>My wife and I started taking MitoQ three weeks ago to test it out.<<

How is it looking?


10 posted on 06/24/2018 7:44:04 AM PDT by freedumb2003 ("We were designed as gardeners, not cubicle rats." (/robroys woman))
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To: freedumb2003
Great question. We believe the greatest amount of our energy and general happiness is coming from the diet, as a whole. We are on a lower carb diet, combined with a 16 hour fast.

We get little exercise and our appetite is now in line with that amount of activity. With carbs, we could always feel like eating something more.

The MitoQ is definitely not hurting us, but I cannot point to it for any immediate benefit. In theory, it should be building up in our mitochondria and help us over time by keeping them healthy and younger.

11 posted on 06/24/2018 7:48:59 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: DIRTYSECRET
#2: "Why can’t these people just lose some weight"

That's what I've always thought. After knowing diabetics in my family and friends, it seems obvious that diabetes is a type of addiction in some people.

Many diabetics crave sugar and will binge on it. I've seen diabetics binge and then give themselves a couple of injections of insulin to compensate, like that was going to fix everything.

Also, when you've been close to diabetics, it's easy to notice when they've been "good" and when they've been off their feed. The mood swings and personality changes will tip you off.

It reminds me of alcoholism, and I bet someday they will show a tie. You can plead with some diabetics, show them the facts, everything. You will get denial, and indignation: "it's my life and I can do what I want", "So what if it kills me, we've all got to die", etc. etc.

I mention all this not to impugn diabetics but to share my thoughts that it is a mystery in many of the same ways as alcoholism, and maybe just as tough a fight to beat it.
 

12 posted on 06/24/2018 7:53:08 AM PDT by Governor Dinwiddie (MAGA in the mornin', MAGA in the evenin', MAGA at suppertime . . .)
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To: 353FMG
My wife and I take that, too.

The Wikipedia reference is useful:

https://en.m.wikipedia.org/wiki/Lipoic_acid

The form our body actually uses is the R-ALA version. It is a racemic molecule (right handed or left handed) and only one exists in nature. Normal manufactured ALA is roughly equal S-ALA and R-ALA.

13 posted on 06/24/2018 7:56:29 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Do you think there’s any benefit to people already diagnosed with diabetes? My son-in-law was diagnosed two years ago and he’s in his 40s, lean, and quite fit. He also does the sugar binge thing then medicates himself. Disturbing to watch. :(


14 posted on 06/24/2018 8:07:17 AM PDT by PistolPaknMama
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To: WildHighlander57

If you decrease your bodies caloric intake and absorption you will lose weight(you can even maintain same foods and exercise level). It is best to decrease caloric intake and eat nutritionally dense foods AND increase exercise if possible. It might be painful from hunger pains and feelings of weakness etc..and difficult to maintain a diet with less available calories but you will lose weight.
As a general rule for each 10 calories lost on a daily basis (every day) one will lose 1 pound in a year. 12 oz. sugared soda is approximatrly 120 cals (some are more)..but if one drinks one of those daily but then stops that practice and maintains every thing dietarily the same...that one can lose 12 pounds in a year. If same person increases ecercise by lets say 120 cals a day....and drops the soda also...well...24 lbs a year. Its that simple as a general rule. It is difficult to maintain daily discipline but if you do...you WILL lose weight.
You cannot manufacture tissue from pure air and pure water. Remember the Biafrans? Did any of them have difficulty losing weight due to insulin resistance?


15 posted on 06/24/2018 8:09:30 AM PDT by Getready (Wisdom is more valuable than gold and diamonds, and harder to find.)
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To: ConservativeMind
"Eating a high fat, high sugar diet has long been known to be a major risk factor for obesity and pre-diabetes

I understand the sugar, of course, and have given that up. But many people swear that if you're diabetic or pre-diabetic, you should eat a "high fat, low carb" diet. Is fat good or not?

16 posted on 06/24/2018 8:21:34 AM PDT by Nea Wood
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To: Governor Dinwiddie

“..it seems obvious that diabetes is a type of addiction in some people.”

Sorry, no. Wish it was. Diabetes is a disease caused not by choice, but by the failure of the body to work within it’s needs.

Weight is not the cause of the illness, it is a part of the affliction. I’m six feet one, and when I was diagnosed with type II I weighed 175 pounds and was easily passing all my physical fitness requirements for the military along with playing sports like basketball, racquetball, and baseball/softball. I was as fit as I could possibly be with a less than 4% body fat measurement according to military doctors.

But because my body was not producing insulin that worked, my body failed to get the use out of the fuel I was consuming. So I wasn’t cutting back on food to lose weight, I was starving the body of nutrients and fuel.

Diets and even starvation will not work as your body will adjust to dampen the failure of muscle use due to lack of fuel until you starve to death. But that doesn’t make your body work correctly.

It actually invites the body to adjust until it will start to shut down functions, or, starvation sepsis. According to Clinical Nutrition ESPEN, a European medical group that studies body needs, food intake in humans is an intermittent process but energy is expended continually. Therefore, humans adapt well to short-term starvation. But the body will break down and start to shut down functions when it is starving of fuel. And all the protein, and other elements you normally consume will not stop it.

And that is the problem diabetics face daily in that balance of consuming enough fuel to live, but not gain or lose weight when the body decides for you that it isn’t going to use the fuel you provided and turns it into fat, or in hypo cases, sends it out of the body. Meantime, you feel like you are exhausted, and the weight adds to the problem as the body doesn’t break it down for use because of the lack of insulin and the insulin you have doesn’t work well.

It’s a delicate balance that you can’t keep up with because of outside needs. And those needs happen from moment to moment in most cases.

rwood


17 posted on 06/24/2018 8:36:25 AM PDT by Redwood71
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To: ConservativeMind
"There is an expensive form of CoQ10 called, “MitoQ.” It does directly migrate into the mitochondria 700-1000 times more than normal CoQ10.

Sounds like a better bargain if it does not cost over 700-1000 times more.

18 posted on 06/24/2018 8:42:55 AM PDT by UnwashedPeasant (I told you so)
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To: ConservativeMind

bump for reference


19 posted on 06/24/2018 8:48:56 AM PDT by Robert357 ( Dan Rather was discharged as "medically unfit" on May 11, 1954.)
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To: 353FMG
"Does anyone know about the benefits of alpha lipoic acid? It is used in Europe to treat diabetes."

Alpha lipoic acid is good stuff, but it is also a potent chelator of mercury. If you have mercury in dental work or accumulated in your body, you have to read up on the proper way to use alpha lipoic acid, or else you will just redistribute a lot of mercury, which could be very bad.

https://www.google.com/search?q=alpha+lipoic+acid+mercury+chelation

20 posted on 06/24/2018 8:51:04 AM PDT by UnwashedPeasant (I told you so)
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