Posted on 02/22/2023 6:25:19 PM PST by Golden Eagle
Far and away the most common question I get from those who took one of the COVID-19 vaccines is: “how do I get this out of my body.” The mRNA and adenoviral DNA products were rolled out with no idea on how or when the body would ever breakdown the genetic code. The synthetic mRNA carried on lipid nanoparticles appears to be resistant to breakdown by human ribonucleases by design so the product would be long-lasting and produce the protein product of interest for a considerable time period. This would be an advantage for a normal human protein being replaced in a rare genetic deficiency state (e.g. alpha galactosidase in Fabry’s disease). However, it is a big problem when the protein is the pathogenic SARS-CoV-2 Spike. The adenoviral DNA (Janssen) should broken down by deoxyribonuclease, however this has not be exhaustively studied.
This leaves dissolution of Spike protein as a therapeutic goal for the vaccine injured. With the respiratory infection, Spike is processed and activated by cellular proteases including transmembrane serine protein 2 (TMPRSS2), cathepsin, and furin. With vaccination, these systems may be avoided by systemic administration and production of Spike protein within cells. As a result, the pathogenesis of vaccine injury syndromes is believed to be driven by accumulation of Spike protein in cells, tissues, and organs.
Nattokinase is an enzyme is produced by fermenting soybeans with bacteria Bacillus subtilis var. natto and has been available as an oral supplement. It degrades fibrinogen, factor VII, cytokines, and factor VIII and has been studied for its cardiovascular benefits. Out of all the available therapies I have used in my practice and among all the proposed detoxification agents, I believe nattokinase and related peptides hold the greatest promise for patients at this time.
(Excerpt) Read more at petermcculloughmd.substack.com ...
Thanks for posting.
bookmark
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According to the Japanese, nattokinase will chew up the spike...
Nattokinase is the active ingredient (responsible for breaking down blood clots) of natto, which is a fermented soybean dish many Japanese eat for breakfast. It was discovered after researchers noticed the Japanese had fewer heart attacks than expected given how much they smoked.
Degradative Effect of Nattokinase on Spike Protein of SARS-CoV-2
by Takashi Tanikawa 1,*,†,Yuka Kiba 2,†,James Yu 3,Kate Hsu 3,Shinder Chen 3,Ayako Ishii 4,Takami Yokogawa 2ORCID,Ryuichiro Suzuki 5,Yutaka Inoue 1ORCID andMasashi Kitamura 2,*
Abstract
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged as a pandemic and has inflicted enormous damage on the lives of the people and economy of many countries worldwide. However, therapeutic agents against SARS-CoV-2 remain unclear. SARS-CoV-2 has a spike protein (S protein), and cleavage of the S protein is essential for viral entry. Nattokinase is produced by Bacillus subtilis var. natto and is beneficial to human health. In this study, we examined the effect of nattokinase on the S protein of SARS-CoV-2. When cell lysates transfected with S protein were incubated with nattokinase, the S protein was degraded in a dose- and time-dependent manner. Immunofluorescence analysis showed that S protein on the cell surface was degraded when nattokinase was added to the culture medium. Thus, our findings suggest that nattokinase exhibits potential for the inhibition of SARS-CoV-2 infection via S protein degradation.
Ping
Praying so....I heard Dr McCullough...who has been repeatedly, and, viciously maligned, here, by the pathetic $hot $hills...say this several months ago....and, have been recommending/sending this to loved ones who took the horrid $hots :-(
FTA ....
...Nattokinase is dosed in fibrinolytic units (FU) per gram and can vary according to purity. Kurosawa and colleagues have shown in humans that after a single oral dose of 2000 FU D-dimer concentrations at 6, and 8 hours, and blood fibrin/fibrinogen degradation products at 4 hours after administration elevated significantly (p < 0.05, respectively). Thus an empiric starting dose could be 2000 FU twice a day. Full pharmacokinetic and pharmacodynamic studies have not been completed, but several years of market use as an over-the-counter supplement suggests nattokinase is safe with the main caveat being excessive bleeding and cautions with concurrent antiplatelet and anticoagulant drugs.
Based on these findings, nattokinase and similar products such as serrapeptase should undergo well-funded, accelerated preclinical and clinical development programs. The issue at hand is the urgency of time, similar to that with SARS-CoV-2 infection and empiric early therapy. It will take up to 20 years to have a fully developed pharmaceutical profile to characterize the safety and efficacy of nattokinase in the treatment of vaccine injury and post-COVID syndromes. Large number of people are sick now and many believe empiric treatment is justified given sufficiently low risk of side effects and potentially high reward. My recommendation is to discuss this with your doctor or seek a specialist in holistic or naturopathic medicine who is experienced with the safety profile of nattokinase in a range of applications....
The article does not let me read it all and it’s pretty complicated. Can anyone summeriize?
That should be fairly easy to test.
Are we seeing problematic levels of the SARS-CoV2 spike protein in the tissues of the vaccinated that aren't present in the unvaccinated who have had Covid?
🤣 well, that is maybe a little TOO mucH of a summary, but I get the idea.
The study cited is in vitro. Lots of substances have been shown to degrade the virus and its spike protein in vitro. In vivo is a whole different matter.
Nattokinase is rich in Vitamin K2 MK7, so I have no doubt it would boost the immune system (in conjunction with Vitamin D and Vitamin K2 MK4). Even early on the pandemic, it was proven that Covid patients low in Vitamin D and K2 fared much worse that those with robust levels.
But a special spike protein zapper? Uh... not proven. Not hardly.
You can buy it from Dr McCullough here if you believe this stuff, though (and save 15% at checkout!):
https://freerepublic.com/focus/f-chat/4123622/posts
The other week this guy was using data from Sinovac which does not use mRNA or DNA (mRNA indirect) at all. This blew the mRNA conspiracy stuff out of the water...wonder if he even knew that? Clearly the people singing his praises on the thread didn’t.
This guy continues to be all over the place.
I figured that without even looking it up that he was selling this stuff. Thank you for confirming my suspicions.
He made no correlation between the Sinovax and mRNA at all, that I can see. His referencing of that study was simply in regard to the dangers of all covid vaccines, per my reading.
It's hard to believe that Dr. McCullough, even though this was not his field of expertise, would not have known this with all of his medical and biological training.
Nattokinase is rich in Vitamin K2 MK7, so I have no doubt it would boost the immune system (in conjunction with Vitamin D and Vitamin K2 MK4). Even early on the pandemic, it was proven that Covid patients low in Vitamin D and K2 fared much worse that those with robust levels.
I remember that quite clearly, especially about Vitamin D, and the discussions about increasing Vitamin K being a bit dicey because that is a coagulant would could worsen blood clotting if not very careful.
That is correct - but I'm not reading that individual article in isolation like it exists in its own stand alone universe - I'm reading it in the context of all of the comments the conspiracy theorists have made as well as his own writings including this one.
PING
Tanikawa et al examined the effect of nattokinase on the Spike protein of SARS-CoV-2. In the first experiment they demonstrated that Spike was degraded in a time and dose dependent manner in a cell lysate preparation that could be analogous to a vaccine recipient. The second experiment demonstrated that nattokinase degraded the Spike protein in SARS-CoV-2 infected cells. This reproduced a similar study done by Oba and colleagues in 2021.Nattokinase is dosed in fibrinolytic units (FU) per gram and can vary according to purity. Kurosawa and colleagues have shown in humans that after a single oral dose of 2000 FU D-dimer concentrations at 6, and 8 hours, and blood fibrin/fibrinogen degradation products at 4 hours after administration elevated significantly (p < 0.05, respectively). Thus an empiric starting dose could be 2000 FU twice a day. Full pharmacokinetic and pharmacodynamic studies have not been completed, but several years of market use as an over-the-counter supplement suggests nattokinase is safe with the main caveat being excessive bleeding and cautions with concurrent antiplatelet and anticoagulant drugs.
Based on these findings, nattokinase and similar products such as serrapeptase should undergo well-funded, accelerated preclinical and clinical development programs. The issue at hand is the urgency of time, similar to that with SARS-CoV-2 infection and empiric early therapy. It will take up to 20 years to have a fully developed pharmaceutical profile to characterize the safety and efficacy of nattokinase in the treatment of vaccine injury and post-COVID syndromes. Large number of people are sick now and many believe empiric treatment is justified given sufficiently low risk of side effects and potentially high reward. My recommendation is to discuss this with your doctor or seek a specialist in holistic or naturopathic medicine who is experienced with the safety profile of nattokinase in a range of applications.
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