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Blue-eyed humans have a single, common ancestor
University of Copenhagen ^ | January 30, 2008 | Unknown

Posted on 01/30/2008 2:10:37 PM PST by decimon

New research shows that people with blue eyes have a single, common ancestor. A team at the University of Copenhagen have tracked down a genetic mutation which took place 6-10,000 years ago and is the cause of the eye colour of all blue-eyed humans alive on the planet today. What is the genetic mutation

“Originally, we all had brown eyes”, said Professor Eiberg from the Department of Cellular and Molecular Medicine. “But a genetic mutation affecting the OCA2 gene in our chromosomes resulted in the creation of a “switch”, which literally “turned off” the ability to produce brown eyes”. The OCA2 gene codes for the so-called P protein, which is involved in the production of melanin, the pigment that gives colour to our hair, eyes and skin. The “switch”, which is located in the gene adjacent to OCA2 does not, however, turn off the gene entirely, but rather limits its action to reducing the production of melanin in the iris – effectively “diluting” brown eyes to blue. The switch’s effect on OCA2 is very specific therefore. If the OCA2 gene had been completely destroyed or turned off, human beings would be without melanin in their hair, eyes or skin colour – a condition known as albinism. Limited genetic variation

Variation in the colour of the eyes from brown to green can all be explained by the amount of melanin in the iris, but blue-eyed individuals only have a small degree of variation in the amount of melanin in their eyes. “From this we can conclude that all blue-eyed individuals are linked to the same ancestor,” says Professor Eiberg. “They have all inherited the same switch at exactly the same spot in their DNA.” Brown-eyed individuals, by contrast, have considerable individual variation in the area of their DNA that controls melanin production.

Professor Eiberg and his team examined mitochondrial DNA and compared the eye colour of blue-eyed individuals in countries as diverse as Jordan, Denmark and Turkey. His findings are the latest in a decade of genetic research, which began in 1996, when Professor Eiberg first implicated the OCA2 gene as being responsible for eye colour. Nature shuffles our genes

The mutation of brown eyes to blue represents neither a positive nor a negative mutation. It is one of several mutations such as hair colour, baldness, freckles and beauty spots, which neither increases nor reduces a human’s chance of survival. As Professor Eiberg says, “it simply shows that nature is constantly shuffling the human genome, creating a genetic cocktail of human chromosomes and trying out different changes as it does so.”


TOPICS: Culture/Society; Miscellaneous; News/Current Events; Technical
KEYWORDS: blueeyes; eugenics; evolution; genetic; genetics; godsgravesglyphs; helixmakemineadouble; incest; mutation
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To: GQuagmire
I’ll play along. I have blue eyes. My parents have brown eyes. Is my father my father? /lol

On the next Maury!

Seriously, the answer is yes, and here's a good explanation: http://www.thetech.org/genetics/ask.php?id=2

181 posted on 01/30/2008 8:04:57 PM PST by mountainbunny
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To: yarddog

I have never seen eye color like that. Wow.


182 posted on 01/30/2008 8:05:52 PM PST by tioga (Beware: conservative with back to the wall. Proceed with extreme caution.)
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To: SevenofNine

183 posted on 01/30/2008 8:07:23 PM PST by monkapotamus
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To: GQuagmire

That is a question for your mother.


184 posted on 01/30/2008 8:21:08 PM PST by Grunthor (Conservative? Juan McCain think that you are a LAZY BIGOT!)
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To: decimon

I wish I could share info like this with my wife, but she’s a 6000 year old earth/Adam and Eve riding dinosaurs creationist and freaks out about such science.


185 posted on 01/30/2008 8:27:00 PM PST by GraniteStateConservative (...He had committed no crime against America so I did not bring him here...-- Worst.President.Ever.)
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To: decimon

:) :) :) :) :)


186 posted on 01/30/2008 9:08:26 PM PST by cubreporter (I trust Rush. He has done more for this country than any of us will ever fully realize.)
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To: decimon

thanks, bfl


187 posted on 01/30/2008 9:45:46 PM PST by neverdem (I have to hope for a brokered GOP Convention. It can't get any worse.)
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To: rfp1234

which ones are Vladimir Putin and which are Daniel Craig?


188 posted on 01/30/2008 9:52:15 PM PST by jmcenanly
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To: decimon

old blue eyes

189 posted on 01/30/2008 9:56:26 PM PST by jmcenanly
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To: decimon
I read a British study that blue eyed men are more likely to marry women with blue eyes, but women with blue eyes are just as likely to marry blue eyed men or brown eyed men. I would include green and just call it fair eyed. I have a theory about the bluest eyes:


190 posted on 01/30/2008 10:06:47 PM PST by Cinnamon Girl (OMGIIHIHOIIC ping list)
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To: GQuagmire

my mom had blue eyes, my dad had brown eyes, we all 9 of us have blue eyes.


191 posted on 01/30/2008 10:09:40 PM PST by television is just wrong
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To: decimon

You may want the send this article to your dad.


192 posted on 01/30/2008 10:11:48 PM PST by trumandogz
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To: SamuraiScot
I can attest to this personally. My eyes are very sensitive to sunlight. I'm always wearing sunglasses. My eyes are a darker blue than my mothers and grandfathers. Theirs were so light they were almost clear--blue/grey.

My father has green/brown hazel eyes. My husband has green eyes. One of my children has dark gray eyes (not blue, not green, not brown) and the other child has greenish/light brown eyes. Very strange combos.

193 posted on 01/30/2008 10:42:48 PM PST by TNdandelion
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To: LukeL
I'm not sure. I wonder if it's like hair? I have a daughter with an unusual shade of red hair. She's the only one in family memory (all sides) with this color hair. I have medium brown hair and my husband has dark blonde. I have read that hair color can be determined when the parents' hair color blends somehow.

This would certainly explain how my brother and I both have blue eyes but a different shade from our blue eyed mother and green/brown/hazel eyed father. Our eyes are darker blue than our mother's. Hers are almost clear/translucent.

194 posted on 01/30/2008 10:49:07 PM PST by TNdandelion
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To: VermiciousKnid

I didn’t have any kind of accident, however my pupils are naturally very dilated. To see my eye color, I would almost have to look at the light. LOL That also explains my sensitivity to light.


195 posted on 01/30/2008 10:58:20 PM PST by TNdandelion
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To: TNdandelion

What is even stranger my mom is brown hair, brown eyes, dad blue eyes brown hair. I was born with blonde hair and blye eyes, now I have dark bown hair and hazel eyes.


196 posted on 01/30/2008 11:11:26 PM PST by LukeL
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To: rfp1234

He would be the perfect antichrist in the Left Behind movies.


197 posted on 01/30/2008 11:17:28 PM PST by proudtobeanamerican1 (Media -)
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To: TNdandelion

Isn’t that interesting? My eyes, like your grandparents’ are such a light blue that they are often described as “clear”. The light doesn’t bother me overmuch, though my son (the one with my eye color) IS bothered by it, and his pupils are indeed much larger than mine, but I doubt anyone would describe them as being unnaturally large.

Regards,


198 posted on 01/31/2008 4:03:59 AM PST by VermiciousKnid
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To: yarddog

Yes it is possible, in fact there are pockets of Chinese that have blue eye and green eyed children. In either case whenever you have the genetic potential to do something generally in a large population someone will.


199 posted on 01/31/2008 5:42:58 AM PST by aft_lizard (born conservative...I chose to be a republican)
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To: yarddog

Yes it is possible, in fact there are pockets of Chinese that have blue eye and green eyed children. In either case whenever you have the genetic potential to do something generally in a large population someone will.


200 posted on 01/31/2008 5:43:11 AM PST by aft_lizard (born conservative...I chose to be a republican)
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