Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Wheat Gluten Confirmed to Promote Weight Gain
The Epoch Times ^ | 7-10-2014 | Sayer Ji

Posted on 07/12/2014 4:11:32 PM PDT by Renfield

New research confirms some of the basic tenets of the Wheat Belly, a book by Dr. William Davis, which argues that wheat avoidance results in healthy weight loss.

Published in Journal of Nutritional Biochemistry this month, and titled “Gluten-free diet reduces adiposity, inflammation and insulin resistance associated with the induction of PPAR-alpha and PPAR-gamma expression,” researchers compared the effects of a gluten-based diet to a gluten-free diet in mice.

Researchers Noted

Gluten exclusion (protein complex present in many cereals) has been proposed as an option for the prevention of diseases other than coeliac disease. However, the effects of gluten-free diets on obesity and its mechanisms of action have not been studied. Thus, our objective was to assess whether gluten exclusion can prevent adipose tissue expansion and its consequences.

Mice were fed either a high-fat diet containing 4.5% gluten (Control) or no gluten (GF). The researchers then assessed the following 16 parameters in both groups:

Remarkably, they found that, relative to the gluten-fed mice, the gluten-free animals showed a reduction in body weight gain and adiposity, without changes in food intake or lipid excretion.

We interpret this to mean that the weight gain associated with wheat consumption has little to do with caloric content per se; rather, the gluten proteins (and likely wheat lectins) disrupt endocrine and exocrine processes within the body, as well as directly modulating nuclear gene expression, e.g. PPAR-α and γ, in such a way as to alter mammalian metabolism in the direction of weight gain.

Sometimes we forget that food is not simply a source of energy, or the material building blocks for the body, but a source of information as well. The way in which food directly interacts with the genes, gene expression, or gene product structure and function, is the object of study of the burgeoning new field of nutrigenomics. Wheat, like anything we attempt to use as food, contains both energy/matter and information that the body will use to maintain its genetic integrity or that may interfere with it.

Certain foods our bodies have had thousands, if not millions of years of adaptation to. Wheat, on the other hand, and particularly its modern permutation, is a biologically and evolutionarily novel new source of both energy/matter and information. In the same way that we have spent intense effort manipulating its genes through selective breeding and hybridization, it is in turn, intensely modifying our own gene expression and related biological pathways.

The researchers stated that the observed results were associated with “up-regulation of PPAR-α, LPL, HSL and CPT-1, which are related to lipolysis and fatty acid oxidation.”

Also, there was an improvement in glucose homeostasis and pro-inflammatory profile-related overexpression of PPAR-γ among the gluten-free animals.

The Researchers Concluded:

Our data support the beneficial effects of gluten-free diets in reducing adiposity gain, inflammation and insulin resistance. The data suggests that diet gluten exclusion should be tested as a new dietary approach to prevent the development of obesity and metabolic disorders.

Discussion

Considering our previous investigation of the weight-promoting effects of wheat in cattle, discussed in our essay The Dark Side of Wheat, we are not at all surprised by these most recent research findings. Wheat grain-fed cattle, while much sicker, are always heavier. Grass-fed, on the other hand, are healthier and yet weighs less. Certainly, therefore, the notion that feeding wheat to mammals may increase their weight is not novel.

The time has come for us to recognize that the consumption of grains, that is, the seed form of the cereal grasses, is a evolutionarily novel behavior. While we have been doing so for 10,000-20,000 years, this is only a nanosecond on the scale of biological time. Albeit, culturally, it may seems like forever.

Weight gain, of course, is only one of over 200 adverse health effects associated with wheat consumption. Whereas weight gain often speaks to our vanity, the reality is that cardiovascular health, psychiatric problems, autism, irritable bowel, and many other common health complaints can be tracked back directly to this “king of grains.” The time has come, we believe, to give wheat and gluten elimination a good try. After all, only your first-hand experience can determine with any certainty whether these concepts are just theory or truth – for you.

This article was originally published on www.GreenMedInfo.com


TOPICS: Agriculture; Food; Health/Medicine
KEYWORDS: gluten; health; nutrition; obesity; wheat; wheatgluten

1 posted on 07/12/2014 4:11:32 PM PDT by Renfield
[ Post Reply | Private Reply | View Replies]

To: Renfield

Would that be GMO gluten or non-GMO gluten?


2 posted on 07/12/2014 4:17:10 PM PDT by BuffaloJack (Unarmed people cannot defend themselves. America is no longer a Free Country.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Renfield

So, red meat, dairy, sugar, corn, rice, and now wheat are certified by “experts” to be bad for me.


3 posted on 07/12/2014 4:18:24 PM PDT by Bryanw92 (Sic semper tyranni)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Bryanw92

The debate is over, the science is settled.


4 posted on 07/12/2014 4:19:23 PM PDT by Perdogg (Ted Cruz-Rand Paul 2016)
[ Post Reply | Private Reply | To 3 | View Replies]

To: BuffaloJack
Would that be GMO gluten or non-GMO gluten?

BINGO!
5 posted on 07/12/2014 4:22:40 PM PDT by Tailback
[ Post Reply | Private Reply | To 2 | View Replies]

To: Bryanw92

Busch and Bud are bad for you. USA regional craft beers are good.

And that science is *settled*. /grin


6 posted on 07/12/2014 4:26:59 PM PDT by ChildOfThe60s ((If you can remember the 60s.....you weren't really there)
[ Post Reply | Private Reply | To 3 | View Replies]

To: Renfield

All horse poop.
ANY carbohydrates are eventual fat cell fillers.
Hispanics have a large propensity for obesity and diabetes. They eat very little wheat, but consume large amounts of corn tortillas.
Almost everything they eat is wrapped in a tortilla.
Dr. Belly Fat’s research was probably funded by the corn lobby.


7 posted on 07/12/2014 4:27:50 PM PDT by doc maverick
[ Post Reply | Private Reply | To 1 | View Replies]

To: Renfield
What about the food pyramid that the experts have been promoting since I was in grade school?

We should be able to sue these so called scientists for all the harm they do with their brain dead ideas.

At a minimum they should have to disclose if their "research" is being funded by someone who has a financial interest in the outcome of their results.

8 posted on 07/12/2014 4:32:08 PM PDT by oldbrowser (We have a rogue government in Washington)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Renfield

Oh noes.

CONFIRMED: Food Makes You GAIN Weight.


9 posted on 07/12/2014 4:34:47 PM PDT by ifinnegan
[ Post Reply | Private Reply | To 1 | View Replies]

To: Renfield

How long did the mice live?


10 posted on 07/12/2014 4:35:47 PM PDT by <1/1,000,000th%
[ Post Reply | Private Reply | To 1 | View Replies]

To: doc maverick
Hispanics have a large propensity for obesity and diabetes. They eat very little wheat, but consume large amounts of corn tortillas.

Corn, wheat, and rice are all grains.

11 posted on 07/12/2014 4:43:50 PM PDT by PapaBear3625 (You don't notice it's a police state until the police come for you.)
[ Post Reply | Private Reply | To 7 | View Replies]

To: All

I’m always fascinated when I come across something like this. I always ask myself, if our society was to be frozen in place, like Pompeii, what would future archeologists surmise about our society from what we were doing, what we were eating, what we were making?

From what I can guess is that the human body was not really designed to thrive using the current energy sources. Processed carb sources provide energy but most likely the wrong type. If that ends up being the case, how do we slowly move away from that is the question. Processed foods have become the norm and not the exception over my lifetime. Our society has chosen the faster and more cost effective full feeling foods versus the slower and more costly base foods. Maybe there is something to it, but I think we need to spend more time researching. Modern science is really in it’s infancy and for all intents we have no idea how processed grains and sugar effect the human body in the long term, because the studies really have only been happening for a few decades and humans evolved over millions of years.

When I was following the Atkins lifestyle, I was almost never hungry and then only after I drank alcoholic beverages. I’ve been following the principles but I still have a pizza and bowl of spags once in a while and I feel great. I read the same from people going Paleo.


12 posted on 07/12/2014 4:48:39 PM PDT by newnhdad (Our new motto: USA, it was fun while it lasted.)
[ Post Reply | Private Reply | To 7 | View Replies]

To: BuffaloJack

Exactly.

We’ve been off almost 100% gmo, high fructose corn syrup
and non-fermented soy for 2 years, and it’s not a miracle but
we’re both down in weight and have much fewer gastro problems.

I make homemade bread using spelt and certified non-gmo grain.

I really believe it’s made a positive difference.


13 posted on 07/12/2014 4:50:21 PM PDT by CaptainPhilFan ( It's hard to kiss the lips at night that chew yer ass out all day long.)
[ Post Reply | Private Reply | To 2 | View Replies]

To: Renfield

This research neglects a lot of extremely important variables, namely the bacteria in the intestinal flora.

(For a quick refresher, biological classification has a hierarchy of eight major ranks. From most encompassing to most specific, they are Domain, Kingdom, Phylum, Class, Order, Family, Genus and Species.)

For example, in the intestinal flora dwells a microorganism that looks like a bacteria, but it actually closer to humans than it is to bacteria. It belongs in a different *Domain* from bacteria, called Archaea. It is called Methanobrevibacter smithii, and it is about the only Archaea in our bodies that we know of.

However, it clearly affects human calorie harvest and body fat indirectly, by strongly improving the efficiency of bacterial digestion of dietary polysaccharides.

Simply put, bacteria digest food, which makes its nutrition more available to the body. In doing so they produce hydrogen gas which limits their action. M. smithii consumes hydrogen gas and converts it to methane, which allows the bacteria to more fully digest food, increasing the body’s calorie harvest.

And this is just one microorganism that influences our weight.

At the phylum level, there is a balance in our digestive flora between the phylum of Firmicutes bacteria and the phylum of Bacteroidetes bacteria. Firmicutes are very good at digesting food, making it much more nutritious when they dominate the balance. Bacteroidetes are less efficient, so we get less nutrition when they dominate.

That is, more Firmicutes than Bacteroidetes, and you will likely gain weight. Change the balance, and you will likely lose weight. Most “probiotic” bacteria are Firmicutes. Bacteroidetes are anaerobic, so you likely cannot get them in a supplement.

Another phylum, called Verrucomicrobia, gives us a single bacteria associated with weight loss. Called Akkermansia muciniphila, it lives in and consumes the mucus of the large intestine, but it causes it to thicken, which helps prevent bad bacteria and their toxins from entering the blood stream through the bowels. This helps reduce the inflammation that leads to weight gain.

At the Genus level, an entire genus of common digestive bacteria, called Enterobacter (Phylum: Proteobacteria), are definitely associated with weight gain. So much so that in obese people, it becomes the dominant bacteria in the flora.

Even viruses can get into the act. Human adenovirus 36 (HAdV-36) or Ad-36 or Adv36 is one of 52 types of adenoviruses known to infect humans. AD-36 is the only human adenovirus that has been linked with human obesity, present in 30% of obese humans and 11% of non-obese humans.

You have to admit that just these are a LOT of variables that should be considered in a study like this one about wheat gluten.

For example, the genus of bacteria that degrade gluten is called Rothia, in the family Micrococcaceae. Researchers noted that: “While the human digestive enzyme system lacks the capacity to cleave immunogenic gluten, such activities are naturally present in the oral microbial enzyme repertoire. The identified bacteria may be exploited for physiologic degradation of harmful gluten peptides.”


14 posted on 07/12/2014 4:51:45 PM PDT by yefragetuwrabrumuy ("Don't compare me to the almighty, compare me to the alternative." -Obama, 09-24-11)
[ Post Reply | Private Reply | To 1 | View Replies]

To: BuffaloJack
Would that be GMO gluten or non-GMO gluten?

LOL! Nice.

15 posted on 07/12/2014 5:16:13 PM PDT by Balding_Eagle (If America falls, darkness will cover the face of the earth for a thousand years.)
[ Post Reply | Private Reply | To 2 | View Replies]

To: Renfield

Yes, wheat is poison. Bill O’Reilly said so. No wonder all the cultures that ever grew wheat have died out. (Sarcasm, for you food nuts)


16 posted on 07/12/2014 5:26:50 PM PDT by ozzymandus
[ Post Reply | Private Reply | To 1 | View Replies]

Eating food causes weight gain? Why did I not know this?


17 posted on 07/12/2014 5:47:51 PM PDT by Rio (Proud resident of the State of Jefferson)
[ Post Reply | Private Reply | To 16 | View Replies]

To: PapaBear3625

But corn and rice don’t have the same type of gluten as wheat has, even though they are all grains.


18 posted on 07/12/2014 5:49:51 PM PDT by FrdmLvr ("WE ARE ALL OSAMA, 0BAMA!" al-Qaeda terrorists who breached the American compound in Benghazi)
[ Post Reply | Private Reply | To 11 | View Replies]

To: Renfield

I have almost totally removed wheat from my diet. I have not lost a pound, I have had some other improvements but no weight loss.


19 posted on 07/12/2014 5:53:52 PM PDT by Ditter
[ Post Reply | Private Reply | To 1 | View Replies]

To: Renfield
New research confirms

Hardly. This is a study released December 17, 2012, conducted by Departamento de Alimentos, Faculdade de Farmácia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, in Brazil.

Personally, I replaced wheat with quinoa as a protein source for a month. Everything else being equal in both nutrition and exercise, I gained seven pounds. I returned to wheat and that weight came off.

20 posted on 07/12/2014 6:22:04 PM PDT by Praxeologue
[ Post Reply | Private Reply | To 1 | View Replies]

To: Renfield
Vladimir Gluten...


21 posted on 07/12/2014 6:27:22 PM PDT by Joe 6-pack (Qui me amat, amat et canem meum.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Bryanw92

Yes. It’s really safest to just eat human flesh.


22 posted on 07/12/2014 6:59:59 PM PDT by Trod Upon (Every penny given to film and TV media companies goes right into enemy coffers. Starve them out!)
[ Post Reply | Private Reply | To 3 | View Replies]

To: Joe 6-pack

LOL!


23 posted on 07/12/2014 7:00:20 PM PDT by Trod Upon (Every penny given to film and TV media companies goes right into enemy coffers. Starve them out!)
[ Post Reply | Private Reply | To 21 | View Replies]

To: BuffaloJack

It may end up not actually being the wheat that is the issue, but the rapid rise method of making modern bread which is responsible for all the gluten problems. Prior to the 1950’s bread was made using a cold fermentation process which altered the gluten so that it was more digestible.

Bread Dread: Are you Really Gluten Intolerant?

http://nourishedmagazine.com.au/blog/articles/bread-dread-are-you-really-gluten-intolerant


24 posted on 07/12/2014 7:00:52 PM PDT by Madam Theophilus (iI)
[ Post Reply | Private Reply | To 2 | View Replies]

To: Trod Upon
There's also Vladimir Puddin'...


25 posted on 07/12/2014 7:02:07 PM PDT by Joe 6-pack (Qui me amat, amat et canem meum.)
[ Post Reply | Private Reply | To 23 | View Replies]

To: Madam Theophilus

And this follow up:

Could This Baker Solve the Gluten Mystery?

http://www.motherjones.com/tom-philpott/2014/02/toms-kitchen-100-whole-wheat-bread-doesnt-suck-and-pretty-easy


26 posted on 07/12/2014 7:04:11 PM PDT by Madam Theophilus (iI)
[ Post Reply | Private Reply | To 24 | View Replies]

To: Renfield

I get headaches from most supermarkets bought bread. The ones I eat have no high fructose corn syrup or msg but there is something in them or more likely probably not labeled correctly as I know the before mention ingredients which do affect me are known by different names.

I can buy bread at a bakery like Abby’s http://www.abbysmillstone.com/ and their bread has no after effect so I figure it is some sort of preservative in the bread at supermarkets. The bakery bread does not last as long before spoiling.

Bread I eat from the supermarket that least affects me: Miltons
http://www.miltonsbaking.com/product-detail/multi-grain
BTW their whole grain crackers are really good.

Anyone have any idea what chemical/ingredients to avoid?


27 posted on 07/12/2014 7:04:41 PM PDT by minnesota_bound
[ Post Reply | Private Reply | To 1 | View Replies]

To: Renfield

I did my own study and found that eating too much food makes you obese....


28 posted on 07/12/2014 7:11:44 PM PDT by Vendome (Don't take life so seriously-you won't live through it anyway-Enjoy Yourself ala Louis Prima)
[ Post Reply | Private Reply | To 1 | View Replies]

To: PapaBear3625

I know that corn, wheat, rice, and starchy foods make me gain weight. It starts slow and then suddenly accelerates to frightening levels. There’s a very strange but definite pattern to it.


29 posted on 07/12/2014 7:57:24 PM PDT by A_perfect_lady
[ Post Reply | Private Reply | To 11 | View Replies]

To: Joe 6-pack

Pretty good, but there’s just something about Vladimir Gluten. Maybe it hearkens back to the days of Soviet bread lines.


30 posted on 07/12/2014 7:57:53 PM PDT by Trod Upon (Every penny given to film and TV media companies goes right into enemy coffers. Starve them out!)
[ Post Reply | Private Reply | To 25 | View Replies]

To: Renfield; All

I always order extra gluten, is it just me?


31 posted on 07/12/2014 8:59:19 PM PDT by gura (If Allah is so great, why does he need fat sexually confused fanboys to do his dirty work? -iowahawk)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Renfield

Heavy stuff.

If this goes viral, there will be a lot of VERY MAD wheat growers.


32 posted on 07/12/2014 9:07:24 PM PDT by BobL
[ Post Reply | Private Reply | To 1 | View Replies]

To: Bryanw92
So, red meat, dairy, sugar, corn, rice, and now wheat are certified by “experts” to be bad for me.

Absolutely - and they are all on the diet I opted to use to lose 20 lbs (11 down 9 to go). Heavy on the meats/other proteins and the rest in moderation. Replaces a very high card (love bread way too much) diet. Net effects are loss of excess weight, more energy (once I got past the initial week of almost zero carbs) and even more regularity in all aspects of bowel movements.

33 posted on 07/13/2014 3:28:56 AM PDT by trebb (Where in the the hell has my country gone?)
[ Post Reply | Private Reply | To 3 | View Replies]

To: oldbrowser

That stupid pyramid should be reversed, Protein, Dairy, fruits and veggies, GRAIN should be the least item consumed.

Not to mention the small factoid they leave out. SUGAR. 1\3rd of your daily calorie intake is from SUGARY Liquids. Chugging them soda’s down by the 2 liter a day is just a way to get FAT faster.

Want to lose weight safe, use a type 2 diabetic diet. Replace all high sugar fruits with low sugar ones. Have a treat now and then. Also brings your cholesterol down. Bake, broil, grill, not breaded meats, no gravies. A drizzle of olive oil and a smidgen of butter add great flavor with the least amount of calories.


34 posted on 07/13/2014 5:04:05 AM PDT by GailA (IF you fail to keep your promises to the Military, you won't keep them to Citizens!)
[ Post Reply | Private Reply | To 8 | View Replies]

To: oldbrowser
What about the food pyramid that the experts have been promoting since . .

You must mean: What about the food pyramid that the food industry has been promoting since . .

35 posted on 07/13/2014 8:46:15 AM PDT by aimhigh (1 John 3:23)
[ Post Reply | Private Reply | To 8 | View Replies]

To: BuffaloJack
would that be GMO gluten or non-GMO gluten

Also, would that be gluten in 100% whole grain bread vs gluten as an additive or gluten in processed grains

FWIW, the only gluten I eat is from 100% whole grains. That seems to be fine.

36 posted on 07/13/2014 8:54:04 AM PDT by grania
[ Post Reply | Private Reply | To 2 | View Replies]

To: Madam Theophilus

> Bread Dread: Are you Really Gluten Intolerant?

I’m not gluten intolerant, however, I have bad gastro problems with GMO wheat products. The non-GMO stuff is fine. When Monsanto modified the wheat to make it toxic to insects, whatever made them think it wouldn’t be toxic to some humans? Since the toxin that make it undesirable to insects is bound to the gluten, people think they are that they are gluten intolerant, when actually they are GMO intolerant.


37 posted on 07/13/2014 3:55:35 PM PDT by BuffaloJack (Unarmed people cannot defend themselves. America is no longer a Free Country.)
[ Post Reply | Private Reply | To 24 | View Replies]

To: BuffaloJack

GMO wheat is not sold in the USA. Since the 80’s modern wheat has been developed so that it has properties of other grains normally not consumed by humans. From what I have read, this is mainly what is causing digestive problems when commercial wheat products are consumed. (See Davis, WHEAT BELLY)

GMO soy beans and corn, however, are consumed in the US.

Whole Foods Information on GMO products:
http://www.wholefoodsmarket.com/about-our-products/product-faq/gmos


38 posted on 07/14/2014 9:24:20 AM PDT by Madam Theophilus (iI)
[ Post Reply | Private Reply | To 37 | View Replies]

To: Renfield; AdmSmith; AnonymousConservative; Berosus; bigheadfred; Bockscar; cardinal4; ColdOne; ...

Soybeans in the diet promote both weight gain and the supposed gluten allergy.


39 posted on 07/15/2014 4:26:04 AM PDT by SunkenCiv (https://secure.freerepublic.com/donate/)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Renfield

1. I am not a mouse
2. Wheat fed the world for millennium going back to the Stone Age
3. Gluten sensitivity doesn’t exist
4. Our lack of activity not our diets are the culprit


40 posted on 07/15/2014 8:51:50 AM PDT by dervish ("We use missiles to protect our people. They use people to protect their missiles")
[ Post Reply | Private Reply | To 1 | View Replies]

To: Renfield

ALL calories add to weight gain. Morons.


41 posted on 07/15/2014 9:09:01 AM PDT by CodeToad (Arm Up! They Are!)
[ Post Reply | Private Reply | To 1 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson