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Spike protein accumulates in the brain and causes infarcts, bleeds, inflammation - Pfizer & Moderna COVID-19 mRNA vaccines cause severe neurological injuries
Dr. William Makis MD ^ | 4/7/2023 | Dr. William Makis MD

Posted on 04/07/2023 6:52:37 PM PDT by george76

A new paper from Germany posted on April 5, 2023 proves that the spike protein accumulates in the brain and causes death of brain cells (which would certainly explain a great deal of what we see around us). (click here)

Key findings:

“Our results revealed the accumulation of the spike protein in the skull marrow, brain meninges, and brain parenchyma.”

“The injection of the spike protein alone caused cell death in the brain, highlighting a direct effect on brain tissue.”

“we observed the presence of spike protein in the skull of deceased long after their COVID-19 infection, suggesting that the spike’s persistence may contribute to long-term neurological symptoms”

Spike protein damage:

Out of all COVID-19 viral proteins, only the spike protein was detected in brain parenchyma.

“suggesting that the spike protein could have a long lifetime in the body. This notion is supported by the observation that spike protein can be detected on patient immune cells more than a year after the infection - a recent preprint suggests spike protein’s persistence in plasma samples up to 12 months post-diagnosis”

“injection of spike protein induced a broad spectrum of proteome changes in the skull marrow, meninges, and brain, including proteins related to coronavirus disease, complement and coagulation cascades, neutrophil degranulation, NETs formation, and PI3K-AKT signaling pathway, demonstrating the immunogenicity of SARS-CoV-2 spike protein in the absence of other viral components.”

Brain inflammation.

“Our molecular analysis suggests activation of immune response in the skull-meninges-brain axis, potentially via recruiting and increasing the activity of neutrophils similar to what has been reported in the respiratory tract”

“in the skull marrow…viral proteins act as an inflammatory stimulus that leads to the development of a significant immune response in the brain”

“In the meninges, a significant consequence of the inflammatory state is an upregulation of proteins involved in neutrophil degranulation”

“Proteins related to the neurodegeneration pathway and damage to the blood-brain barrier were the most prominent dysregulated molecules in the brain.”

“viral spike protein leads to the activation of RHOA, which triggers the disruption of blood–brain barrier”

Blood clots, mini-strokes, brain bleeds..

“The dysregulation of the complement and coagulation pathways was detected in both the skull marrow and the brain. This might explain the observed propensity of COVID-19 patients to develop mini-infarcts in the brain parenchyma and our observation of an increased level of micro-bleedings in COVID-19 patients, potentially contributing to the observed brain damage in the COVID-19 patients in acute or chronic stages”

Spike protein and Neurological diseases..

“We identified several candidate proteins with no previous association with COVID-19, especially those earlier associated with neurological diseases…notably, their role has been associated with disorders such as Parkinson’s disease, Alzheimer’s disease, and dementia”

“To further pinpoint the consequences of spike protein-specific effects in the brain tissue beyond the acute inflammatory response…We identified several dysregulated proteins associated with neurodegeneration”

“significantly impairs mitochondrial function…a source of oxidative stress reported in…long-term symptoms such as chronic fatigue”

How Spike protein gets into the brain..

“Our data may also suggest a mechanism for the virus’s entry into the central nervous system. In both mouse and COVID-19 human tissues, we find spike protein in the SMCs (skull-meninges connection), which the virus or virus components could use to travel from the skull marrow to the meninges and the brain parenchyma”

“virus might take other routes to reach the brain in a not mutually exclusive way. For example, the virus could traverse the cerebrovasculature to reach the brain parenchyma or be carried there by immune cells (via neutrophils or phagocytic cells)”

“Brain invasion of virus-shed spike protein found in some COVID-19 cases has been linked to a compromised blood-brain barrier and trafficking along the olfactory nerve or vagus nerve. Here, we suggest an alternative scenario wherein SARS-CoV-2 spike protein reaches first the skull marrow and then the meninges before entering the brain.”

“Spike-induced alterations in the skull-meninges-brain axis present diagnostic and therapeutic opportunities as both skull and meninges are easier to access than brain parenchyma”

My substacks on psychosis post COVID-19 vaccination:

March 9, 2023 - Children who were injured by Pfizer or Moderna COVID-19 mRNA vaccines - Hallucinations, self-harm, suicide attempts, permanent disability (click here)

March 8, 2023 - COVID-19 vaccine induced psychosis - 13 cases of post vaccine psychosis, mania & suicide attempts that will shock you..

My Take…

This is an extremely important paper from Germany (we will never see this kind of research done in Canada).

This paper proves that the SARS-CoV2 and COVID-19 mRNA vaccine spike protein enter the skull marrow, meninges and the brain parenchyma.

The spike protein disrupts the blood brain barrier.

The spike protein alone causes cell death in the brain, it activates complement and coagulation pathways that lead to blood clots, mini infarcts and brain bleeds, it causes inflammation, and local changes associated with neurodegeneration (dementia, Alzheimer’s, Parkinson’s Diseases).

I believe that neurological injury is one of the biggest categories of COVID-19 mRNA vaccine injury. These injuries are extremely common, and we have only begun to see the long term effects of spike protein accumulation in the brain.

Beyond the strokes, aneurysms and brain bleeds, the vision and audiovestibular problems, all kinds of paralysis and movement disorders, I believe that among the COVID-19 mRNA vaccinated, we will see a huge spike in neurodegenerative disorders, mental health disorders and an overall increased risk of suicide.


TOPICS: Conspiracy; Health/Medicine; Science; Weird Stuff
KEYWORDS: adverseevents; ama; bigpharma; bigpharmatrollshere; bioweapon; bloodclots; brain; brainbleeds; braincells; chinavirus; chinavirusvaccine; covid19; death; deathjabs; deathshots; ecg; ekg; electrocardiogram; experimental; faa; frindecline; genetherapy; germany; getsumlearnin; heartinflammation; ivermectin; mediumrare; mediumwell; mrna; mrnagenetherapy; myocarditis; neurologic; neurological; nutcase; pericarditis; pilots; poison; qtardfantasy; quack; qvirus; rare; rona; sads; safelydefective; semicallcenter; spikeprotein; stroke; strokes; substackingdollars; suddenly; suicides; trypanophobia; vaccine; vaccineinjury; vax; vaxx; vaxxed; vaxxes
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To: BipolarBob

We have friends (couple, in their mid 50’s) who were PREVIOUSLY very healthy/active/athletic ... until they each got their original two $hots, and, now...each have had TWO boooo$ters.

They have been REPEATEDLY sick....with china virus (three times) and one is now dealing with terrible vein (in leg) issues. The other had a knee replacement surgery that refuses to heal (has had a pic line, etc.)

They STILL haven’t figured out that it could be due to a completely whacked immune system. We have begged them to please NOT get any more boosters.

So sad.


21 posted on 04/07/2023 7:35:39 PM PDT by Jane Long (What we were told was a conspiracy theory in ‘20 is now fact. Land of the sheep, home of the knaves)
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To: Jane Long; cuz1961; OHPatriot; chuck allen
Injecting spike protein to skull marrow niches directly in healthy mice triggered proteome changes and cell death in the brain parenchyma.

I know it's probably too much to expect an anti-vaxer to read, but really. This is embarassing.

"Injecting spike protein to skull marrow niches directly in healthy mice triggered proteome changes and cell death in the brain parenchyma."

The paper says nothing, repeat, nothing, about vaccines.

Just because the grifter Dr. Makis lies about the paper's implications doesn't mean you need to lap it up.

22 posted on 04/07/2023 7:39:07 PM PDT by semimojo
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To: OHPatriot

Have a friend whose a retired virologist who warned me to get no where near the MRA vaccine, so being a doc, having to be exposed daily to the virus, I got the J&J jab aaaand ended up with horrible tinnitus.

From now on, I would rather die on my feet than live on my knees.

Will never trust our government or news media again.


23 posted on 04/07/2023 7:40:11 PM PDT by lizma2
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To: BipolarBob

SIL?


24 posted on 04/07/2023 7:44:53 PM PDT by lizma2
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To: semimojo; cuz1961; OHPatriot; chuck allen

Oh....of course.....Dr Makis is yet ANOTHER grifter.

That’s all you $hot $hill trolls have got.

Give it up.

How many $hots have you had? You’re either a paid $hill, or....worried.


25 posted on 04/07/2023 7:45:03 PM PDT by Jane Long (What we were told was a conspiracy theory in ‘20 is now fact. Land of the sheep, home of the knaves)
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To: lizma2

Sister in law .... son in law ..... (can be used, for both).


26 posted on 04/07/2023 7:45:46 PM PDT by Jane Long (What we were told was a conspiracy theory in ‘20 is now fact. Land of the sheep, home of the knaves)
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To: Jane Long
Dr Makis is yet ANOTHER grifter.

So what's you explanation for why he's lying about the paper?

That’s all you $hot $hill trolls have got.

Ah, a conspiracy theory that I'm being paid for my posts.

I guess when all the world's a conspiracy why shouldn't FReepers get in on it.

27 posted on 04/07/2023 7:48:12 PM PDT by semimojo
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To: semimojo

LOL...you’re using ALL of your call center words, tonight.....grifter doc....conspiracy theorist....

Give it up, troll.

Take your drive by smear attempts elsewhere. No one, here, buys the bunk you’re $hilling.


28 posted on 04/07/2023 7:51:35 PM PDT by Jane Long (What we were told was a conspiracy theory in ‘20 is now fact. Land of the sheep, home of the knaves)
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To: Jane Long

Haven’t seen any rise in eye infections but thanks for the heads up!


29 posted on 04/07/2023 7:57:15 PM PDT by lizma2
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To: Jane Long
LOL...you’re using ALL of your call center words, tonight.....grifter doc....conspiracy theorist....

Wow, I'm not only getting paid I have a call center behind me (who are they calling, BTW? C-SPAN?)

Someone posts a stupid article by some guy who lies about the content of a paper and when I point that out you don't address the facts at all, you call names. Or should I say name$.

And by the way, when you accuse someone of secretly being paid to post you are by definition describing a conspiracy.

Why don't you want to own your own comments?

Do you just want to propose conspiracy theories without acknowledging that they really are conspiracy theories?

30 posted on 04/07/2023 7:57:57 PM PDT by semimojo
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To: george76

“You’ve had a very violent reaction to something.”


31 posted on 04/07/2023 7:58:59 PM PDT by blueunicorn6 ("A crack shot and a good dancer” )
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To: Dogbert41

Dittoes


32 posted on 04/07/2023 8:01:44 PM PDT by drSteve78 (Je suis Deplorable STILL . )
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To: lizma2

Sister In Law common acronym


33 posted on 04/07/2023 8:03:45 PM PDT by BipolarBob (Not my fault, yer Honor. I went to the Alec Baldwin School of Firearms Handling. )
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To: semimojo

semimojo wrote:
“”I believe that neurological injury is one of the biggest categories of COVID-19 mRNA vaccine injury. These injuries are extremely common, and we have only begun to see the long term effects of spike protein accumulation in the brain.””

“There wasn’t a word in there about vaccines.”

“The damage being noted is from spike proteins from Covid infection.”

“Seems one would want to do everything they could to avoid or reduce the severity of infection from such a virus.”
.......................................
Yes, they are attempting to deflect and blame the effects of MRNA gene therapy on the flue virus again!

SS1


34 posted on 04/07/2023 8:08:43 PM PDT by Spitzensparkin1 (Donate often, it is our FReeping ammo. Help keep the supply train rollin', be a monthly donor. )
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To: Paladin2

Please let me know if you get any good answers to that question.


35 posted on 04/07/2023 8:13:03 PM PDT by Arcadian Empire (The Baric-Daszak-Fauci spike protein, by itself, is deadly.)
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To: george76

A message from the boss:

04/07/23 | Jim Robinson

Wouldn’t it be great if we could complete this FReepathon in under 60 days? Please get your donations in early and let’s get ‘er done! Thank you very much! Your support is greatly appreciated! God bless you.


36 posted on 04/07/2023 8:16:31 PM PDT by Mark (DONATE ONCE every 3 months-is that a big deal?)
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To: Jane Long

Well said.


37 posted on 04/07/2023 8:19:20 PM PDT by Arcadian Empire (The Baric-Daszak-Fauci spike protein, by itself, is deadly.)
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To: lizma2; ransomnote

All versions of the poison vax have the same goal: to flood people’s bodies with spike proteins.

The spike proteins, by themselves, are deadly.


38 posted on 04/07/2023 8:22:42 PM PDT by Arcadian Empire (The Baric-Daszak-Fauci spike protein, by itself, is deadly.)
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To: Paladin2

I thought you’d never ask: https://freerepublic.com/focus/f-chat/4133137/posts


39 posted on 04/07/2023 8:28:30 PM PDT by The Duke
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To: george76
Covid NOT Responsible for ‘Explosion’ in Heart Deaths, Major Study Shows Slay News April 6, 2023

Over 100M Americans May Now Have ‘Seriously Damaged’ Hearts, Top Cardiologist Warns Slay News April 4, 2023

40 posted on 04/07/2023 8:43:13 PM PDT by TigersEye (Woke is a cancer of the mind and humanity)
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