Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Goodbye Cigarettes – Scientists Discover Potential Treatment for Nicotine Dependence
Scitech Daily ^ | OCTOBER 5, 2023 | By UNIVERSITY OF MISSOURI-COLUMBIA

Posted on 10/05/2023 11:40:19 AM PDT by Red Badger

Researchers found that theta-burst transcranial magnetic stimulation (TBS) can improve self-control, resulting in reduced cigarette cravings and decreased smoking. The study revealed that people with nicotine dependence show different brain structures and functions, with these differences possibly affecting their inhibitory control, making it harder to resist the urge to smoke.

Theta-burst transcranial magnetic stimulation treatment could reduce cigarette cravings. A recent study from the University of Missouri School of Medicine indicates a potential alternative method to address cigarette cravings.

The research demonstrates that by using theta-burst transcranial magnetic stimulation (TBS) – powerful and quickly changing magnetic pulses that influence brain activity – individuals may experience enhanced self-control, diminished cravings, and subsequently, decreased cigarette consumption.

People with nicotine dependence tend to have significant structural and functional differences in the brain, compared to healthy non-smokers. Smoking cigarettes has been shown to be associated with less grey matter, which means they have fewer neurons and other cells in the brain.

Research suggests these differences may affect inhibitory control (IC), which is our control over automatic urges and response to stimuli – what enables humans to stop an impulsive reaction to something.

“Having difficulties with IC may make it harder to avoid smoking when the urge arises, in response to all the cues and contexts in the environment that trigger the behavior to light a cigarette,” said lead author Brett Froeliger, PhD, professor of Psychiatry.

TBS refers to when magnetic pulses are applied to the brain in bursts of three and come in two forms: continuous TBS (cTBS) and intermittent TBS (iTBS). cTBS consists of applying these three bursts repeatedly for 40 seconds, whereas iTBS applies the same number of pulses irregularly for more than 190 seconds.

Magnetic stimulation has been used to treat other mental illnesses and disorders. cTBS has been experimentally tested to treat generalized anxiety disorder, whereas iTBS to the left dorsolateral prefrontal cortex – a part of your brain responsible for cognitive processes – is FDA-approved for treating major depressive disorder.

The study involved 37 participants, mostly in their late 40’s, and examined the effects of both cTBS and iTBS to the right inferior frontal gyrus, a brain region heavily involved with IC. Researchers found that cTBS improved IC, whereas both cTBS and iTBS reduced cravings and, subsequently, smoking.

“Identifying treatments that improve IC may help reduce smoking and can potentially help with preventing relapse following when a person attempts to quit smoking,” Froeliger said. “Treatments that improve IC may also help disrupt the cycle of drug use among individuals with other substance use disorders; however, further research is needed to examine the clinical value of TBS for treating substance use disorders.”

Reference:

“Effects of Hyperdirect Pathway Theta-Burst Transcranial Magnetic Stimulation on Inhibitory Control, Craving, and Smoking in Adults with Nicotine Dependence: A Double-Blind Randomized Crossover Trial” by Spencer Upton, Alexander A. Brown, Muaid Ithman, Roger Newman-Norlund, Greg Sahlem, Jim J. Prisciandaro, Erin A. McClure and Brett Froeliger, 9 August 2023, Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

DOI: 10.1016/j.bpsc.2023.07.014


TOPICS: Agriculture; Business/Economy; Health/Medicine; Military/Veterans
KEYWORDS: smoking; smokingcessation; tbs; tobacco
Navigation: use the links below to view more comments.
first 1-2021-36 next last

1 posted on 10/05/2023 11:40:19 AM PDT by Red Badger
[ Post Reply | Private Reply | View Replies]

To: Red Badger

Now if they can get the potheads off of pot. Maybe the price of Cheetos and Doritos will go back down.


2 posted on 10/05/2023 11:41:47 AM PDT by FlingWingFlyer (Prosecutors say Trump may have broken the law admiring gun in South Carolina" ROTFLMAO!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger

I gotta do somethin!! Cigs are over $10 a pk now up here in Michigan!!


3 posted on 10/05/2023 11:44:07 AM PDT by sit-rep
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger

4 posted on 10/05/2023 11:44:14 AM PDT by ConservativeInPA
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger

JUST STOP!!!!

You will have 2 or 3 days of withdrawal symptoms, and they you’re done.

Quit on a Friday, when you start climbing the walls remember- it’s just a withdrawal symptom.

Drink lots of Orange juice and Xanax, and try to sleep it off, over the weekend.

By Monday you’ll be smoke free.

All those nicotine patches do is prolong the withdrawals so DON’T USE THEM.


5 posted on 10/05/2023 11:45:17 AM PDT by Mr. K (No consequence of repealing Obamacare is worse than Obamacare)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger

So we will just have recreational tobacco now?


6 posted on 10/05/2023 11:48:07 AM PDT by Delta 21 (If anyone is treasonous, it is those who call me such.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger
Theta-burst transcranial magnetic stimulation treatment

What? I'll pass, thanks.

7 posted on 10/05/2023 11:50:43 AM PDT by Fido969 (45 is Superman! )
[ Post Reply | Private Reply | To 1 | View Replies]

To: sit-rep

Go for a drive waaaay out in the wilderness at a park where there aren’t any stores. Stay out there for the weekend, or longer. Don’t take any money with you, empty your ash tray and clean the car completely.

Walk around in nature, enjoy the outdoors and by Monday you will not even miss them.................


8 posted on 10/05/2023 11:51:18 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
[ Post Reply | Private Reply | To 3 | View Replies]

To: Red Badger

I’ve tried everything else, maybe I should try taping magnets to my forehead......


9 posted on 10/05/2023 11:55:14 AM PDT by Hot Tabasco
[ Post Reply | Private Reply | To 1 | View Replies]

To: sit-rep

I quit cold turkey from 3 to 4 packs a day to none. It sucked. That was a long, long, long time ago. $10 would buy a carton or two in those days.

Cold turkey. Just do it.


10 posted on 10/05/2023 12:19:23 PM PDT by fretzer
[ Post Reply | Private Reply | To 3 | View Replies]

To: sit-rep

I remember the good old days ordering from reservations and having cartons delivered to my home. So convenient and so much cheaper.


11 posted on 10/05/2023 12:23:31 PM PDT by peggybac (My will is what I wanted. God's will is what I got.)
[ Post Reply | Private Reply | To 3 | View Replies]

To: Red Badger

How does it work for ice cream addicts?
That’s my problem.


12 posted on 10/05/2023 12:27:15 PM PDT by keats5
[ Post Reply | Private Reply | To 1 | View Replies]

To: fretzer

I could never smoke or be around smoke when I was nauseous or sick. I got the mini flu and after 3 days I realized the nicotine was probably out of my system and decided to quit smoking altogether. I read that when you quit you become a bit nauseous, which was great for me. I had no problem and only had a minor craving after about 10 days. I know recovering addicts and alcoholics who said giving up drug/drink was easy compared to smoking. I can understand.


13 posted on 10/05/2023 12:28:03 PM PDT by peggybac (My will is what I wanted. God's will is what I got.)
[ Post Reply | Private Reply | To 10 | View Replies]

To: sit-rep

3.25 at the Rez Tobaccanist.
I’d still like to quit.


14 posted on 10/05/2023 12:33:36 PM PDT by Big Red Badger (The Truman Show)
[ Post Reply | Private Reply | To 3 | View Replies]

To: Red Badger

Important...don’t hang around smokers !


15 posted on 10/05/2023 12:37:17 PM PDT by tet68 ( " We would not die in that man's company, that fears his fellowship to die with us...." Henry V.)
[ Post Reply | Private Reply | To 8 | View Replies]

To: tet68

Exactly!..................or place where smoking is common, bars, pool halls, restaurants, sports events, Boys HS Restrooms.....................🤦‍♀️


16 posted on 10/05/2023 12:45:27 PM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
[ Post Reply | Private Reply | To 15 | View Replies]

To: Red Badger

Hey, they’re trying to take all the fun out of being addicted to tobacco.


17 posted on 10/05/2023 12:51:04 PM PDT by antidemoncrat
[ Post Reply | Private Reply | To 1 | View Replies]

To: Red Badger

Scientists Discover Potential Treatment for Nicotine Dependence

$100 a pack cigarettes?


18 posted on 10/05/2023 12:52:56 PM PDT by Macoozie (Handcuffs and Orange Jumpsuits)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Mr. K

It’s not that simple. The urge for a cig is constant, any time life is annoying it’s there. In the 90s Lou Reed gave an interview where he was talking about his clean life. He’d quit almost everything a few years before. He said of them all, heroine, coke, booze, and smokes it was the smokes that he still craved every single day.


19 posted on 10/05/2023 12:53:01 PM PDT by discostu (like a dog being shown a card trick)
[ Post Reply | Private Reply | To 5 | View Replies]

To: Mr. K

Orange juice and Xanax...
.
Heck of a Weekend FRiend !


20 posted on 10/05/2023 1:22:11 PM PDT by Big Red Badger (The Truman Show)
[ Post Reply | Private Reply | To 5 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-36 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson