Posted on 10/01/2004 6:33:21 AM PDT by JohnHuang2
Crone's Disease sufferer.
I am disabled permanently from Crohn's. There is no cure. I have endured five major surgeries and may be looking at another. If you have or know someone who has this disease, tell them to gather ALL the information they can.
More like its major symptom.
There is a far more prevalent incidence of irritable bowel syndrome in the US than there is of Crohn's disease. I wonder if it has the same cause?
More evidence to confirm the theory.
Bump for later.
Another reason that confimrs my decision to rarely buy hamburger or other ground-meat products. Best to have it all in one piece, and smart shopping means you can buy cheap cuts for only $1 more per lb. than hamburger.
I know someone with Chrohns. She grew up on a dairy farm. Coincidence? I'll forward this article to her.
Did you ever receive sulfasalazine or mesalamine treatment??
Try liquid Silver.
You have a mean streak in there, don't cha? LOL, LOL, LOL !
So why doesn't pasturizing kill the bacteria? That's the point, right?
Bacterial DNA within granulomas of patients with Crohn's disease--detection by laser capture microdissection and PCR.
Ryan P, Kelly RG, Lee G, Collins JK, O'Sullivan GC, O'Connell J, Shanahan F.
Alimentary Pharmabiotic Centre; and Departments of Medicine, Histopathology, Microbiology, and Surgery, University College Cork, National University of Ireland, Ireland.
OBJECTIVES: We previously reported the use of laser capture microdissection (LCM) and PCR to detect the presence of Mycobacterium paratuberculosis DNA in granulomas of patients with Crohn's disease. While this does not imply a cause-effect relationship, it may influence the disease process because bacterial DNA has immunomodulatory effects. The aim of this study was to determine whether DNA from nonmycobacterial commensals, such as Escherichia coli, is also increased in the granulomas of Crohn's disease. METHODS: Archival tissue from 15 surgical cases of Crohn's disease and 10 non-Crohn's granulomatous bowel disease controls were examined. Granulomas were isolated using LCM, and the extracted DNA was examined for presence of E. coli DNA by nested PCR amplification of a 135 base-pair segment of the uidA gene. RESULTS: E. coli DNA was detected in microdissected granulomas in 12/15 Crohn's disease patients and in 1/10 non-Crohn's control granulomas (p < 0.001). Also, E. coli DNA was detected in 8/15 Crohn's full-thickness sections and in 4/10 control full-thickness sections. CONCLUSIONS: E. coli DNA may be detected more frequently in Crohn's granulomas than in other non-Crohn's bowel granulomas. This may indicate a tendency for lumenal bacteria to colonize inflamed tissue, or may be due to increased uptake of bacterial DNA by gut antigen presenting cells. In light of previous detection of M. paratuberculosis DNA in Crohn's granulomas, the nonspecific nature of the type of bacterial DNA present in granulomas is evidence against any one bacterium having a significant causative role in Crohn's disease. Copyright 2004 American College of Gastroenterology
PMID: 15307874 [PubMed - indexed for MEDLINE]
Thank you for this article. My brother suffered from Crohn's...it's an awful disease.
I used to have lots of bowel problems until I stopped drinking milk. After reading this I imagine many people could get better by just not drinking the stuff. I also about a year or two ago took some of those internet colon cleanser pills. Amazingly enough they got rid of a tapeworm that I had had for years. I felt good as new after that regimen of pills.
All that being said, with all the pharma's making billions off their drugs like vioxx and so forth, isn't it about time we put an end to their nonsense. The FDA isn't doing a damn bit of good, and really never has, meanwhile these new drugs are getting pushed through while the newer and apparently better alternatives are being sidelined. It just really looks like drug companies are completely profit driven.
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