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Keyword: methylation

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  • Pentagon’s Giant Blood Serum Bank May Provide PTSD Clues

    08/13/2013 8:09:47 PM PDT · by neverdem · 7 replies
    Scientific American ^ | August 12, 2013 | Dina Fine Maron
    The massive repository of genetic material is poised to advance research—just don’t bother asking for your samples back Inside DoDSR Image: Dina Fine Maron SILVER SPRING, Md.—Nestled inside a generic-looking office building here in suburban Maryland, down the hall from cable-provider Comcast, sits the largest blood serum repository in the world. Seven freezers, each roughly the size of a high school basketball court, are stacked high with row upon row of small cardboard boxes containing tubes of yellow or pinkish blood serum, a liquid rich in antibodies and proteins, but devoid of cells. The freezers hover at –30 degrees Celsius—cold...
  • Child abuse leaves lasting 'scars' on DNA - Lingering marks on DNA could amplify stress responses.

    02/23/2009 1:34:04 AM PST · by neverdem · 34 replies · 1,981+ views
    Nature News ^ | 20 February 2009 | Heidi Ledford
    Victims of childhood abuse can carry chemical changes to their DNA into adulthood.Punchstock Suicide victims with a history of abuse during childhood are more likely to carry chemical changes to their DNA that could affect how they respond to stress as adults, a study has found. Those with no history of childhood abuse did not show the same pattern of DNA modification, and had normal expression of NR3C1, a gene linked to stress responses. But the findings do not mean that the effect of childhood abuse is indelible, cautions Joan Kaufman, a psychologist at Yale School of Medicine in New...
  • Epigenetics reveals unexpected, and some identical, results

    01/25/2009 11:03:50 PM PST · by neverdem · 9 replies · 541+ views
    Science News ^ | January 18th, 2009 | Tina Hesman Saey
    One study finds tissue-specific methylation signatures in the genome; another a similarity between identical twins in DNA’s chemical tagging Tattoos on the skin can say a lot about person. On a deeper level, chemical tattoos on a person’s DNA are just as distinctive and individual — and say far more about a person’s life history. A pair of reports published online January 18 in Nature Genetics show just how important one type of DNA tattoo, called methylation, can be. Researchers at Johns Hopkins University report the unexpected finding that most DNA methylation — a chemical alteration that turns off genes...
  • Science Now Explains The Uniqueness of Every Human Being From Conception

    08/20/2008 8:39:33 AM PDT · by Apollos21K · 30 replies · 148+ views
    Dakota Voice ^ | 8/17/2008 | SD Legislature
    ...The invention of the PCR techniques has led to further refinements of the DNA fingerprinting techniques, which has given science the ability to obtain a human being's DNA fingerprinting – and therefore his or her identity – from a single cell. There can no longer be any doubt that each human being is totally unique from the very beginning of his or her life at fertilization. (Mark, P. 19-21.) The significance of methylation of cytosine was unknown until 1985. It has a profound significance in understanding...that the human being is whole and complete at fertilization. A human being at an...
  • Lasting genetic legacy of environment (Epigenome).

    12/20/2007 2:20:13 PM PST · by Jedi Master Pikachu · 11 replies · 510+ views
    BBC ^ | Thursday, December 20, 2007. | Monise Durrani
    Environment can change the way our genes work Environmental factors such as stress and diet could be affecting the genes of future generations leading to increased rates of obesity, heart disease and diabetes.A study of people suffering post-traumatic stress disorder (PTSD) after the 9/11 attacks in New York made a striking discovery. The patients included mothers who were pregnant on 9/11 and found altered levels of the stress hormone cortisol in the blood of their babies. This effect was most pronounced for mothers who were in the third trimester of pregnancy suggesting events in the womb might be responsible....
  • The Need for Speed

    08/27/2007 6:19:11 PM PDT · by Maelstorm · 8 replies · 331+ views
    The Sanger Institute ^ | 12th July 2007 | The Human Epigenome Project (HEP)
    A difference of only a few percent in DNA sequence is thought to separate the human and chimp genomes. New research published in Genome Biology identifies the subset of sequences that may have driven the evolution of our two species.The researchers propose that the key changes lie in regions of our genome that control the activity of genes. It is managers of the genome, rather than the workforce, that have been most responsible for differences between chimps and humans.A team led by scientists from the Wellcome Trust Sanger Institute looked at DNA elements called conserved non-coding regions (CNCs) in human,...
  • Fantastic Voyage : Live Long Enough to Live Forever

    05/25/2006 2:20:45 PM PDT · by Momaw Nadon · 19 replies · 1,043+ views ^ | September 27, 2005 | Ray Kurzweil & Terry Grossman, M.D.
    Immortality is within our grasp . . . In Fantastic Voyage, high-tech visionary Ray Kurzweil teams up with life-extension expert Terry Grossman, M.D., to consider the awesome benefits to human health and longevity promised by the leading edge of medical science--and what you can do today to take full advantage of these startling advances. Citing extensive research findings that sound as radical as the most speculative science fiction, Kurzweil and Grossman offer a program designed to slow aging and disease processes to such a degree that you should be in good health and good spirits when the more extreme...