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Scientists believe that aging can increase the spread of ovarian and other cancers. Now, researchers have found that ovarian cancer cells can spread more easily in tissues that are senescent or aged because these tissues secrete a unique extracellular matrix that attracts the spreading cancer. What they found was that the cancer cells chose to settle down more on the aged tissues; moreover, they settled closer to the aged normal cells in the cell sheets. To figure out what was drawing the cancer cells to the aged cells, the team first wondered if they were being attracted to signaling molecules...

Yesterday the Expose published an article which highlighted just a few of the various diseases that were found to be potentially caused by parasites, including cancers. A recent review of nine published research papers by Doctor William Makis further supports the views in the article, but Dr Makis is more qualified to say “it is a reasonable hypothesis that COVID-19 mRNA Vaccine Turbo Cancer patients could benefit significantly from anti-parasitic drugs.” One anti parasitic drug in particular, Fenbendazole, however, has not been sanctioned for human use by the FDA, but despite lacking “official” approval, it is cheap, safe and more...

In an internationally conducted clinical trial lead by Dana-Farber involving patients with recurrent ovarian cancer that is resistant to platinum therapy, a novel conjugate therapy called mirvetuximab soravtansine resulted in substantially better responses than standard treatments. Mirvetuximab soravtansine was granted accelerated approval November 2022. "The results of the SORAYA study supported the accelerated FDA approval of mirvetuximab for patients with recurrent, platinum-resistant, folate receptor alpha-positive ovarian cancer," Ursula A. Matulonis, MD. The study enrolled 106 patients with platinum-resistant high-grade serous ovarian cancer that highly expressed folate receptor alpha. The participants had been treated with up to three prior treatments for...

Cancer cells (blue) are deactivated. Credit: Imperial College London ______________________________________________________________________ Scientists at the Ovarian Cancer Action Research Centre at Imperial College London have discovered a mechanism that deactivates ovarian cancer cells. The findings, published in EMBO Reports, could lead to better treatments for women with ovarian cancer. The research has found a new mechanism for a protein named OPCML. This protein is known as a tumour suppressor, as it prevents cells turning cancerous. However OPCML is usually lost in cancer patients. Scientists have now found that when OPCML is put back into cancer cells, it cleverly deactivates a type...

A team of researchers led by the UAB has found the first ancient remains of a calcified ovarian teratoma, in the pelvis of the skeleton of a woman from the Roman era. The find confirms the presence in antiquity of this type of tumour -- formed by the remains of tissues or organs, which are difficult to locate during the examination of ancient remains. Inside the small round mass, four teeth and a small piece of bone were found. Teratomas are usually benign and contain remains of organic material, such as hair, teeth, bones and other tissues. There are no...

Two independent groups working with advanced-stage cases say the drug extended the period before the disease worsened by more than 3.5 months. Avastin can stabilize tumors in women suffering from advanced-stage ovarian cancer, extending the period before the disease worsens by more than 3.5 months, according to the results of two large, international clinical trials conducted by separate research teams. The findings, published in Thursday's edition of the New England Journal of Medicine, come less than a week after the European Commission approved Avastin for treating women newly diagnosed with advanced ovarian cancer. The drug, known generically as bevacizumab, has...

Ultra-fast freezing of ovarian tissue from women who have lost their fertility as a result of cancer treatment can lead to it being used in transplants with the same success rate as fresh tissue, a researcher told the 25th annual conference of the European Society of Human Reproduction and Embryology 29 June. Dr. Sherman Silber, Director of the St. Louis Infertility Centre, St. Louis, Missouri, USA, said that freezing tissue by the vitrification method, which avoids ice formation, meant that oocyte (egg) viability was almost identical with that seen in fresh oocytes. Dr. Silber and colleagues used standard viability testing...

Eleven million people around the world - 23,000 of them Israeli - will have been diagnosed with cancer by the end of 2006, according to Prof. Peter Boyle, head of the World Health Organization's International Agency for Cancer Research (IACR) based in Lyon, France. But Israeli researchers, "who are among the best in the world," are helping to increase the survival rates of more patients, he said, pointing to an experimental device originally developed in the Israeli defense industry that has the potential to provide earlier and better diagnoses. The Histocan, which includes a tiny air-driven camera, is being tested...

Last year, members of the Alliance for Nanotechnology in Cancer based at Northeastern University and the Massachusetts Institute of Technology demonstrated that acid-sensitive polymer nanoparticles could boost the delivery of anticancer drugs into the acidic interior of tumors. Now, that same group of investigators has shown that these nanoparticles are effective at suppressing tumor growth when tested in an animal model of human ovarian cancer. In addition, animals treated with this nanoparticle formulation do not appear to experience adverse side effects that often limit the ability of patients to tolerate chemotherapy. The researchers reported the results of their preclinical work...

Have just finished reading the numerous replies -- some of them truly heart breaking -- of this evening's post "Lost an Old Friend Today. Politics and the Personal"; and I find that far and away most of these intense,friendship-breaking liberals mentioned in these posts are women. (Obviously, not all.) Add to this that in many news stories it seems to be chiefly women who protest this or that by climbing trees or running around with their blouses off; or that when it come to really off-the-wall legal ruling(s), college admin. decisions, local government declarations, etc. odds are pretty darn good...

Monkey born after ovarian tissue transplant 12.03.2004 LONDON - A monkey has given birth to a healthy baby created from an egg taken from transplanted ovarian tissue, in a breakthrough scientists say could lead to new fertility treatment for women with cancer. The baby, named Brenda, is the first primate born using an egg taken not from a working ovary but from parts of the ovary implanted elsewhere in the mother's body. This tissue contains cells that can develop into eggs, without needing a full ovary. The egg was then removed, fertilised and the embryo was transplanted into a surrogate...