Vitamin D supplementation may slow diabetes progression

Medical XPress ^ | July 26, 2019 | European Society of Endocrinology

[ConservativeMind]

Vitamin D supplementation may slow the progression of type 2 diabetes in newly diagnosed patients and those with prediabetes. The study findings suggest that high-dose supplementation of vitamin D can improve glucose metabolism to help prevent the development and progression of diabetes.

Although low vitamin D levels have previously been associated with an increased risk of developing type 2 diabetes, some studies have reported no improvement in metabolic function. However, these often had a low number of participants or included individuals with normal vitamin D levels at the start who were metabolically healthy, or who had long-standing type 2 diabetes. Whether vitamin D supplementation has any beneficial effect in patients with prediabetes or with newly diagnosed diabetes, especially in those who have low vitamin D levels, remains uncertain.

This study examined the effect of vitamin D supplementation on glucose metabolism in patients newly diagnosed with type 2 diabetes or identified as at high risk of developing the condition. Markers of insulin function and glucose metabolism were measured before and after six months of high-dose vitamin D supplementation (approximately 5-10 times the recommended dose). Although only 46% of study participants were determined to have low vitamin D levels at the start of the study, supplementation with vitamin D significantly improved the action of insulin in muscle tissue of participants after six months.

Dr. Claudia Gagnon says, "The reason we saw improvements in glucose metabolism following vitamin D supplementation in those at high risk of diabetes, or with newly diagnosed diabetes, while other studies failed to demonstrate an effect in people with long-standing type 2 diabetes is unclear. This could be due to the fact that improvements in metabolic function are harder to detect in those with longer-term disease or that a longer treatment time is needed to see the benefits."

[Fresh Wind]

What sort of K2 dosage is appropriate?

[ConservativeMind]

Interesting wrap up on K and K2s:

https://www.ncbi.nlm.nih.gov/books/NBK222299/?report=classic#__NBK222299_dtls__

[Fresh Wind]

Thank you! The adequate intake is what I needed to know.

[ConservativeMind]

There is no Upper Tolerable Limit for Vitamin K.

https://www.consumerlab.com/m/RDAs/

We take a combined form with standard K, K2-MK4, and K2-MK-7.

Examples:

https://www.luckyvitamin.com/p-1029350-life-extension-super-k-with-advanced-k2-complex-90-softgels

Or

https://www.vitacost.com/vitacost-ultra-vitamin-k-includes-advanced-k2-complex

We have taken two of those pills a day for extended periods of time and never had any issues. We are now just taking one a day.

The MK-7 form floats through the body for up to a week until it’s needed.

[Freedom4US]

Didn't reach my goal by New Years day, but averaged 1.67 lbs a week for the last 6 months, lost 47 pounds so far. Intermittent fasting works great. One meal a day. No exercise to speak of. In fact mostly sedentary. Bought a scale recently and have a better handle on calorie count. Did have, and will undoubtedly have, some setbacks along the way. The Chocolate Cake Incident, and that hamburger casserole... If I could have stayed more focused it would have been a faster rate of loss. More important is gaining the benefits that healthy eating patterns give. (I'm not going to start eating Kale smoothies and dry whole-sawdust toast and all that BS.) But I don't want to become prediabetic or get Insulin resistance or screw up my liver, inflammation and all the weird stuff that happens with being obese. Lots of stuff that I thought was part of aging might be related too, at least anecdotally. Memory seems way better, and focus. Back pain, knee pain and stomach issues, I really recommend this. Thanks for your encouragement and experience. I'll try to stick with this for life.