Posted on 01/02/2018 1:27:46 PM PST by nickcarraway
Although their goal was to cure diabetes, scientists may have stumbled onto a new medication to help treat the devastating effects of Alzheimer’s disease.
According to a press release from researchers at Lancaster University, a new drug being tested for diabetes patients was found to have “significantly reversed memory loss” in test subjects and is now being examined as possible treatment for neurodegenerative disorders.
The medication, known as a triple receptor drug — or “triple agonist” — reportedly works in multiple ways to protect the brain against degeneration and promote growth. Researchers say that a study of mice being given the drug found that the animals had an increased ability to learn and retain memories.
“These very promising outcomes demonstrate the efficacy of these novel multiple receptor drugs that originally were developed to treat type 2 diabetes,” Professor Christian Holscher said in the release.
The scientists added that the mice showed a decrease in chronic inflammation and amyloid plaques in the brain, which have been linked to the development of Alzheimer’s in people.
“With no new treatments in nearly 15 years, we need to find new ways of tackling Alzheimer’s,” Dr. Doug Brown of the Alzheimer’s Society said. “It’s imperative that we explore whether drugs developed to treat other conditions can benefit people with Alzheimer’s.”
The discovery of the diabetes drug’s side-effect is not a complete coincidence to the researchers. The findings, published in the journal Brain Research, point to the link between some of the symptoms of diabetes and their link to Alzheimer’s. Insulin desensitisation is not only one of the key effects suffered by diabetes patients, the hormone’s lack of production has also reportedly been observed in the brains of people affected by the memory-stealing disorder.
Bookmarking so I don’t forget to come back and read it.
Bookmarking so I don’t forget to come back and read it.
I would never remember to check my bookmarks.
Good, the patients can remember to take their diabetes drugs.
How much metformin are you taking?
For anyone with diabetes or diagnosed as pre-diabetic, there are two vital supplements that are commonly used in Europe to help protect against diabetic damage.
First is Vitamin B1. Diabetics urinate more than typical, and this can deplete their supply of albumin, leading to kidney problems. But taking an ordinary supplement of B1 helps to restore and maintain the albumin.
Second is stabilized (NA) R-Alpha Lipoic Acid (ALA). Lipoic Acid normally comes in two forms, R- and S-, but only the R- form is helpful. But R-ALA is normally unstable. Yet a company figured out how to stabilize it with sodium.
So all told, you need NA R-ALA, or stabilized R-ALA.
In any event NA R-ALA protects and even helps regrow peripheral nerves and improve blood flow there. Diabetic peripheral neuropathy, nerve damage in the extremities which can lead to some of the horrific damages of diabetes.
Okay, well this two are givens, but there are other OTC products that are a huge help.
Gymnema Sylvester, or just Gymnema, is an herb nicknamed “the sugar killer”. It blocks absorption of sugar in the intestines, may actually stimulate the release of insulin and improve insulin sensitivity. It really slams that blood sugar down, which you can prove to yourself with a simple blood test.
Turmeric helps in several ways, including the stimulation of the production of insulin in the pancreas and improved sensitivity. Its effects are actually enhanced with a little black pepper.
Ginger not only improves blood sugar but also lowers hbA1c, the other diabetes blood test.
And there are others.
Bookmark your bookmarks...
Recommend the Case Against Sugar by Gary Taubes. It will help reinforce that decision to reduce sugar. High glycemic carbs are poison.
Or simply quit eating what is killing you?
Understand though. A nation of diabetic fat asses needs “sugar killers” and tricks to avoided making dietary changes.
Something like this is always of interest to me, so thank you, Red Badger!
Haven’t had but a couple of weak drinks a year, and no soda pop for nearly five years.
Haven’t lost a quarter ounce. Niente. Bupkus.
“Here’s another, Metformin, a type-2 diabetes drug”
My Mom has metastasized Uterine Cancer. Liver and Lung Lesions after Hysterectomy/Radiation failed to localize the cancer. Just finished her six rounds of standard care Chemo. Additionally she joined a drug trial which added Metformin / Placebo. Metformin regulates glucose, cancer loves sugar to continue to divide.
We are not sure she received metformin vs placebo, but five of her six lesions were reduce to basically nothing and no longer a concern. On lung lesion is being stubborn which they are working on an immunotherapy regiment.
Viagra (originally called Micoxafloppin)
My mother, who did not have diabetes, and ate mostly sweets, died of Alzheimer’s. My mother-in-law, who also, did not have diabetes, and lived mostly on sweets, lived to be 100, and only developed some mild dementia the last few months of life, so “one size” definitely does not “fit all” We’ve started a keto diet, because in type two diabetics, it usually removes the condition (doctors rarely refer to anyone as being “cured” of diabetes, even if their lab work becomes completely normal), results in large amounts of weight loss (if overweight), and causes one to have increased energy, and a reduction in depression. There is a definite correlation between diabetes, consumption of high carbohydrate diet, and neuro disorders, but obviously, not in everyone. Carbohydrates, especially simple carbs, such as are found in foods made with white flour or sugar, have an effect on our brains, much the same as recreational drugs do. Apparently, the pleasure centers of the brain light up like a Christmas tree, on brain imaging, when sugar or recreational drugs are taken. Interesting stuff.
850MG twice daily. With this dosage, my A1C is 6.2.
Great to hear. I lost weight when I increased the Metformin dosage.
God Bless your mother.
Just reducing sugar is not enough, though. Decreasing carbs, while increasing fats, causes the body to revert to fat stores for energy. Weight loss is faster and greater on the high fat, moderate protein, very low carb diet. Doesn’t sound like eating a lot of fat would work, but it does. The studies done have shown so, plus, bad cholesterol levels drop, heart disease drops, despite high fat (including animal fat) intake. I lost around 8 lbs (one dress size) in a couple of weeks on this diet, and my A1c, which is never too high, but moderately so, was the lowest ever. It was just a tad higher than a non-diabetic. And being allowed extra fat, kind of makes up for the deprivation you feel when you take out most of the carbs in your diet. Eating a cupful of strawberries with a huge blob of whipped heavy cream and a little natural sugar substitute, doesn’t feel like dieting, but it is.
Later, if I remember.
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Viagra (originally called Micoxafloppin)
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ha ha ha ha
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