Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Pathways that extend lifespan by 500 percent identified
Science Daily ^ | 1/8/20

Posted on 01/21/2020 5:14:06 PM PST by LibWhacker

Summary: Scientists have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research. The increase in lifespan would be the equivalent of a human living for 400 or 500 years, according to one of the scientists. Share:

Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research.

The increase in lifespan would be the equivalent of a human living for 400 or 500 years, according to one of the scientists.

[...snip...]

"The synergistic extension is really wild," said Rollins, who is the lead author with Jianfeng Lan, Ph.D., of Nanjing University. "The effect isn't one plus one equals two, it's one plus one equals five. Our findings demonstrate that nothing in nature exists in a vacuum; in order to develop the most effective anti-aging treatments we have to look at longevity networks rather than individual pathways."

The discovery of the synergistic interaction could lead to the use of combination therapies, each affecting a different pathway, to extend healthy human lifespan in the same way that combination therapies are used to treat cancer and HIV, Pankaj Kapahi, Ph.D., of the Buck Institute, has said...

The synergistic interaction may also may explain why scientists have been unable to identify a single gene responsible for the ability of some people to live to extraordinary old ages free of major age-related diseases until shortly before their deaths.

(Excerpt) Read more at sciencedaily.com ...


TOPICS: Health/Medicine; Science
KEYWORDS: aubreydegrey; extend; lifespan; longevity; pathways
Navigation: use the links below to view more comments.
first 1-2021-29 next last
So there's still hope. As soon as they figure out how to turn you into a nemotode worm.

BOOM! Beat the Doubting Thomas's to the punch. ;-)

1 posted on 01/21/2020 5:14:06 PM PST by LibWhacker
[ Post Reply | Private Reply | View Replies]

To: LibWhacker

But we only have 10 11 or 12 years left right? 500 years? These guys must be climate deniers!


2 posted on 01/21/2020 5:19:58 PM PST by xp38
[ Post Reply | Private Reply | To 1 | View Replies]

To: LibWhacker

There’s just so much we can learn from nematodes.

They’re getting ready to launch a spaceship to Mars.


3 posted on 01/21/2020 5:21:33 PM PST by blueunicorn6 ("A crack shot and a good dancer")
[ Post Reply | Private Reply | To 1 | View Replies]

To: LibWhacker

With my luck, this will hit the market for only $20 a month in 2045.

When I’m in my late 80’s.

Hell, I’m not sure I’d be interested in it if it was for sale at that price now.


4 posted on 01/21/2020 5:22:42 PM PST by The Antiyuppie (“When small men cast long shadows, then it is very late in the day”)
[ Post Reply | Private Reply | To 1 | View Replies]

To: LibWhacker

My life span will be eternal because of Jesus. Who wants to keep living in a failing mortal body?


5 posted on 01/21/2020 5:25:45 PM PST by beethovenfan (Mene, Mene, Tekel, Upharsin)
[ Post Reply | Private Reply | To 1 | View Replies]

To: All

I didn’t read the article but . . the secret is beer, right?


6 posted on 01/21/2020 5:26:19 PM PST by BipolarBob (Just imagine the /s after everything I post and we'll all be happier.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: LibWhacker

Who would want to live that long!? Not me!


7 posted on 01/21/2020 5:28:18 PM PST by vpintheak (Leftists are full of "Love, peace" and bovine squeeze.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: xp38

LoL!


8 posted on 01/21/2020 5:30:37 PM PST by CondoleezzaProtege
[ Post Reply | Private Reply | To 2 | View Replies]

To: LibWhacker

9 posted on 01/21/2020 5:30:40 PM PST by equaviator (There's nothing like the universe to bring you down to earth.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: LibWhacker

Bring on Gerovita (an old reference for former liberals like myself).


10 posted on 01/21/2020 5:30:50 PM PST by Tolerance Sucks Rocks (Show me the people who own the land, the guns and the money, and I'll show you the people in charge.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: BipolarBob

Cocaine and hookers.


11 posted on 01/21/2020 5:31:26 PM PST by EEGator
[ Post Reply | Private Reply | To 6 | View Replies]

To: LibWhacker

I’ll test it.


12 posted on 01/21/2020 5:32:40 PM PST by wastedyears (The left would kill every single one of us and our families if they knew they could get away with it)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Tolerance Sucks Rocks

I think my retirement money will run out long before that.

Maybe we have to work until we are 350 yrs old?

Who will hire a 300 yr old geezer?


13 posted on 01/21/2020 5:33:26 PM PST by oldasrocks (Heavily Medicated for your Protection.)
[ Post Reply | Private Reply | To 10 | View Replies]

To: LibWhacker

Imagine another 500 years of Hellary, Pelosi, et al.


14 posted on 01/21/2020 5:34:57 PM PST by bgill
[ Post Reply | Private Reply | To 1 | View Replies]

To: LibWhacker

Nematodes...
Hold on there. Is this something you have to eat, or can you just rub it on?


15 posted on 01/21/2020 5:36:09 PM PST by Buttons12
[ Post Reply | Private Reply | To 1 | View Replies]

To: EEGator

I picked a bad week to alienate my drug dealers and pimps.


16 posted on 01/21/2020 5:37:14 PM PST by BipolarBob (Just imagine the /s after everything I post and we'll all be happier.)
[ Post Reply | Private Reply | To 11 | View Replies]

To: vpintheak

“You are not yet ready for immortality” - Kosh Naranek.


17 posted on 01/21/2020 5:39:22 PM PST by wally_bert (Your methods were a little incomplete, you too for that matter.)
[ Post Reply | Private Reply | To 7 | View Replies]

To: LibWhacker

As an undergrad at UCSD around 1984-85, I attended an evening talk on life extension.

The speaker said with our knowledge at the time, it was possible for humans to live much longer, healthy lives well into our 120th year or so.

A voice in mid-audience said “oh, great, we’ll NEVER get rid of the department chairman” (who happened to be in attendance).

The laughter was immediate, raucous, and followed by sporadic outbreaks as the comment was repeated to those who didn’t quite catch it.

One of the funniest things I’d ever heard in school.

Here’s a thought: George Soros, Nancy Pelosi, Nadler, Schitt, live to 500?

Yeah, I’m a buzzkill.


18 posted on 01/21/2020 5:48:01 PM PST by normbal (normbal. somewhere in socialist occupied America)
[ Post Reply | Private Reply | To 1 | View Replies]

To: LibWhacker

Lazarus Long...paging Mr. Lazarus Long...


19 posted on 01/21/2020 5:55:16 PM PST by seowulf
[ Post Reply | Private Reply | To 1 | View Replies]

To: LibWhacker

No thanks, unless they also find a way to eliminate painful ailments like arthritis, and loss of hearing and eyesight, etc. One can only take so much pain and disability.


20 posted on 01/21/2020 5:55:54 PM PST by Rocky
[ Post Reply | Private Reply | To 1 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-29 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson