Posted on 12/27/2022 6:41:40 AM PST by MtnClimber
Well, here's the medical facts that entirely explain why people with more shots get more covid.
I've been paying attention to this possibility for a while but until the study work came out that proved it all there was is speculation. ADE ("Antibody dependent enhancement") is a fairly poorly-understood thing; most people believe it is confined to making a particular infection more serious than it would otherwise be. Of course having it occur when it otherwise would not fits that quite-nicely, but isn't what people tend to think about.
Now, unfortunately, we have the evidence. Here's the salient graph and lots of discussion which I'll try to recap for you here:
Let me explain this one for you because it makes very clear what's going on. There are multiple sub-types of IgG antibodies. IgG are the last ones that show up; IgA typically is in the mucosa of the nose, and is a "front line" of defense if you will. IgM shows up second; it generally is gone about two weeks or so after you recover. IgG is the "long term" antibody recognition but it has multiple subtypes.
This is very important for human and animal life, because not all things that can elicit a serious immune response should get one. For example: A bee sting. A serious immune response to that could kill you and in people seriously-allergic that's a real risk. So why don't most people get a serious immune response?
As it turns out they sort of do, but its focuses in one sort of IgG build, IgG4, which suppresses the cascade of events that cause the body to go after the thing in question and destroy it, along with all the side effects that produces (fever, serious inflammation, etc.)
Well, when you get Covid typically IgG3 is the one that neutralizes most of the virus. IgG1 and 2 do some of the work, but most of it is done by IgG3. You're not supposed to build an IgG4 response, and with natural infection without vaccination you don't, thus there's no inhibition and your response is and remains effective at neutralizing whatever it is. Typical vaccines (e.g. measles) elicit a response that looks exactly like an actual infection because that's how they're designed and intended; they use the whole virus and their intent is to make your body think it is being invaded by the real deal and respond as it would to the real deal.
SNIP
Remember, IgG4 causes the body to tolerate the infection rather than attack and clear it.
This turns you into a walking virus mutation and production factory, a source of infection to everyone around you and, to the extent that the virus does direct damage to your body systems, and we know the spike does, it also is likely to lead to very severe long-term problems that look like other conditions. Nobody is looking for spike damage specifically in, for example, heart attacks, strokes and pulmonary embolisms, never mind the possibility of potentiating cancer by suppressing immune response if that suppression and tolerance goes beyond Covid, and it very well might. If that's not bad enough everyone that got jabbed has the same profile of response where the normal situation is that responses differ in different people because our body systems operate slightly differently (we're all genetically unique.)
Now who's most-likely to have had the most number of jabs and thus are walking around tolerating infections and giving them others? Health care workers! And who goes to the hospital or doctor? Compromised individuals who can least-withstand infections. Gee, that was smart, right?
What's worse is that we do not know if this is local to Covid or even just coronaviruses. It might not be. We may now have created a couple hundred million people in the US alone who have coded their immune systems to tolerate certain proteins that are common across all manner of respiratory viruses and worse, if its not local to viruses to be more-susceptible to cancer and other immune-sensitive problems with no way to reverse the effects!
You are right that choosing to get the jabs may be a FU.
I gave you a summary article which does have some of the links.
And the lead article on this thread has them too.
You might have noted I quoted from your Mayo Clinic link and pointed out it treated the immune system on an elementary school level of understanding.
Which is why I called it propaganda.
I want you to read and learn for yourself.
But it’s not at the “I F’ing Love Science” hippy-dippy level you’re used to.
Here are just a couple from within today’s links, a layer or two down.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0262162
(duplicated here) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8726489/
https://www.jci.org/articles/view/152070
https://www.medrxiv.org/content/10.1101/2022.07.05.22277189v1.full.pdf
https://www.science.org/doi/10.1126/sciimmunol.ade2798
A non-peer review (summary article) of the mortality trends :
https://igorchudov.substack.com/p/excess-mortality-is-worse-than-it
Don't have a link handy, but I thought one of the issues with gp120 is that the viruses were pulled into the lympocytes and turned them into zombies: they didn't necessarily die, but became ineffective, hindering the rest of the immune response; and this effect was behind the observation that the Japanese didn't have as many problems: because as heavy smokers, the nicotine increased the turnover of these cells. I may be remembering wrong, it might have been some other immune cell. Posting in case it jogs anyone else's memory.
PING to 64.
The pic from the top of the FR posting, is
from
Supplementary Materials of https://www.science.org/doi/10.1126/sciimmunol.ade2798
and I found that referenced here
https://jessicar.substack.com/p/the-immunological-mechanism-of-action?utm_source=substack&utm_medium=email
and I found that link in the comments to
I <3 your tagline.
“Another interesting parallel between HIV and SARS-CoV-2 has been observed. Both viruses possess a protein labeled gp120. This protein enables entry into T lyphocytes and subsequently kills them. In this respect both viruses induce an immune system deficiency. The consequence is that opportunistic infections kill the person with the immune system deficiency.”
In the 1980s, A friend’s health was declining because of HIV. His father paid to have me help improve my friends health. The money was to buy foods, and supplements to enhance health. In Sept. when he walked to the store a block away and returned he was exhausted. His T4 count was 400, a low level. I purchased 8 or 10 supplements I thought would improve his health, and recommended some diet changes as well as stopping cocaine use. He took the supplements regularly, improved his health, and cut back on his cocaine. He also began telling me about his abusive relationships with his mother and father. For example when he told his father about his mother’s drunken sexual abuse when he was seven, His father threw his mother down the stairs, and badly mistreated the son. At any rate around Christmas we walked 4 blocks and back to a nice food botique in a snow storm to make a celebratory dinner. His T4 count had risen to 1100. A good level. I counseled several other people on improving their nutritional health and saw improvements. I also saw extremely damaging family relationships which contributed to more rapid death. The day in spring 2020 when someone asked Fauci if taking Vitamin C and D3 could help and he said NO, I was just sick to hear it. Finally, by Novemeber, even he had to admit those nutrients might be helpful.
One of the big problems in medicine today is that most research is being done on drugs. Very little is done on nutrition, and supplements. Fauci has been controlling $6billion in NIH research funding for many years. I have been researching colon and prostate cancers for my brother and my partner. I have noticed some interesting early studies in the early 2000s, but see little sign that original suggestions for further research have been followed. We need to lobby our Congresscritters to demand more money be spent to find nutritional ways to improve our national health.
My brother and my partner have been following my nutrition and supplement recommendations, and their doctors are pleased with their response to the conventional treatments they have received—chemotherapy, anti-testosterone, and radiation. More follow-up testing to be done soon.
Yep....that last link, is the one I posted to you, and Appy, upthread.
Here’a a couple of choice comments from the discussion on the rintrah link you sent.
= = = = =
From the study:
https://www.science.org/doi/10.1126/sciimmunol.ade2798
>IgG4 antibodies among all spike-specific IgG antibodies rose on average from 0.04% shortly after the second vaccination to 19.27% late after the third vaccination.
= = = = =
IgG3 Vs IgG4 and the antitumor response.
I always like to cross check these things, to the immune system cancer cells are just another pathogenic invader to destroy.
As suspected this is important and the implications aren’t good.
B Cell Orchestration of Anti-tumor Immune Responses: A Matter of Cell Localization and Communication (2021)
somatic hypermutation (SHM)
“Additionally, analysis of more than 5,000 TCGA RNA-seq samples revealed that high levels of IgG3–1 switch are associated with prolonged survival in patients with high SHM rates, whereas IgG3–1 levels are not prognostic in low SHM samples, underscoring the role of SHM in generating BCR sequences with high binding affinity to the exposed tumor antigens (Hu et al., 2019).”
https://www.frontiersin.org/articles/10.3389/fcell.2021.678127/full
***
How to select IgG subclasses in developing anti-tumor therapeutic antibodies (2020)
“IgG3 demonstrates the highest affinity binding to most FcγRs”
“IgG4 only has high affinity for FcγRI but weak affinities for all other receptors, and is a poor inducer of Fc-mediated effector functions.”
https://jhoonline.biomedcentral.com/articles/10.1186/s13045-020-00876-4
= = = = = =
Also found this – Fc-Fc interactions of IgG4 may affect immune evasion of cancers, regardless of the antigen specificity of the IgG4.
An immune evasion mechanism with IgG4 playing an essential role in cancer and implication for immunotherapy
“We further found that IgG4, **regardless of its antigen specificity**, inhibited the classic immune reactions of antibody-dependent cell-mediated cytotoxicity, antibody-dependent cellular phagocytosis and complement-dependent cytotoxicity against cancer cells in vitro, and these effects were obtained through its Fc fragment reacting to the Fc fragments of cancer-specific IgG1 that has been bound to cancer antigens. We also found that IgG4 competed with IgG1 in reacting to Fc receptors of immune effector cells. Therefore, locally increased IgG4 in cancer microenvironment should inhibit antibody-mediated anticancer responses and help cancer to evade local immune attack and indirectly promote cancer growth. ”
https://pubmed.ncbi.nlm.nih.gov/32819973/
= = = = = =
“I know several people with sudden onset, rapid growing cancers; two are dead already. Is this because they can’t fight the cancers because the only IgG they are making is IgG4?”
One reason the cancers are sparking is because the spike protein shuts down our BRCA1 and 53BP1 DNA repair mechanisms. It sucks up the proteins needed for repair. Our DNA fractures trillions of times a day, but our body repairs or patches it. Failure to repair these fractures leads to DNA degradation, a major cause of cancer.
At the same time, the mRNA instructs our CD8 killer T-cells to express spike protein. This makes them look suspiciously like viruses. What do CD8 killer T cells do? They kill viruses, bacteria and cancerous cells. So when they see each other expressing spike, they kill each other, they kill themselves, antibodies (and antibody compliments) are produced to kill them. Net result, they die off catastrophically. So the vaccinated lose the ability to fight cancer. Or bacterial infections. Or viruses. This is not a coincidence. This is a bioweapon.
For example
https://clinicaltrials.gov/ct2/show/NCT04583410
https://pubmed.ncbi.nlm.nih.gov/32790936/
https://www.cebm.net/covid-19/nicotine-replacement-therapy/
It revolves around the binding and displacement of the spike from the Ace2 receptors by nicotine.
They don't necessarily encourage smoking but I have seen anecdotal evidence that the use of nicotine gum in small amounts helps with smell/taste problems. YMMV
“The insurance companies are seeing all cause mortalities up 40% above what their long historical actuarial data would expect.”
https://www.macrotrends.net/countries/WLD/world/death-rate
World - Historical Death Rate Data
Year Death Rate
2022 7.678
2021 7.645
2020 7.612
2019 7.579
2018 7.546
2017 7.570
2016 7.594
So, divide the 7.678 rate for 2022 by the 7.579 rate for 2019 - that is a 1.33% increase in the mortality rate. That may be significant, but I don’t know where you’re getting your 40% figure.
Anyway, I see your point - they can use all-causes mortality statistics without relying on the bogus Covid statistics.
Thanks....great info.
That last paragraph offers a pretty basic explanation.
This has to be scary to a lot of folks. Just heartbreaking, what these evil monsters have done to our families....friends....citizens.
I can understand why many of them prefer denial. :-(
I think you have found the source of the problem:" Fauci has been controlling $6billion in NIH research funding for many years."
When Big Pharma contributes 60% of the funding source of NIH/FDA/CDC national healthcare,
these agencies have a vested financial interest in maintaining the source of Pharma's continued income.
That is why Fauci directs Federal research funds into continuing research in those areas where Pharma benefits.
I recall that FDA/ CDC used to mock the use of various vitamin and mineral supplements and attempted to stifle their use to control common illnesses.
To the best of my recollection, I don't believe that recent medical graduates of modern medicine are even educated in the use of vitamins and minerals,
but rather are trained to provide medications to manage illness.
The natural reaction to most illness is to prescribe a medication to eliminate the symptoms, and you just "take a pill"
Medicine has become a reactive response to disease and illness;
if you are able to cure the illness before it takes root, you eliminate much of the profit motive of big pharma.
Thanks for posting; no time right this minute though.
40% was for a specific age range, IIRC 45-64 which is typically a group with known but not too large death rates.
From thehill.com in June, but it was bandied about on other sources in January 2022.
Yup!
It’s VERY interesting.
Of course, vaccination’s protection against severe disease is mediated through T cells, not through antibodies. I saw a preprint last night that claims there’s no cellular immune boost after 3 doses of an mRNA vaccine (that is, 4, 5, etc don’t ADD to protection against severe disease).
But the IgG4 story as a cause of repeated non-severe infections looks good as well.
So these articles prove your theory?
“The clot shots cause your body to make antibodies that tell the body to ignore the COVID virus.” which implies they cause it to ignore the virus rather than create the antibodies to attack it.
The articles you referenced that I perused did not make that claim. It seems like you created the claim and then went in search of evidence to support it. The beautiful thing about science is that you can find anything you want if you can use vagueness as a criteria.
The Mayo Clinic article was rather succinct because the science was obvious. That’s how vaccines work.
Once again, it is a blog that is designed to tell you what you want to hear. That’s how they get hits. You may as well post an article from CNN.
FDA on suppler,emits
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