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Blue-eyed humans have a single, common ancestor
University of Copenhagen ^ | January 30, 2008 | Unknown

Posted on 01/30/2008 2:10:37 PM PST by decimon

New research shows that people with blue eyes have a single, common ancestor. A team at the University of Copenhagen have tracked down a genetic mutation which took place 6-10,000 years ago and is the cause of the eye colour of all blue-eyed humans alive on the planet today. What is the genetic mutation

“Originally, we all had brown eyes”, said Professor Eiberg from the Department of Cellular and Molecular Medicine. “But a genetic mutation affecting the OCA2 gene in our chromosomes resulted in the creation of a “switch”, which literally “turned off” the ability to produce brown eyes”. The OCA2 gene codes for the so-called P protein, which is involved in the production of melanin, the pigment that gives colour to our hair, eyes and skin. The “switch”, which is located in the gene adjacent to OCA2 does not, however, turn off the gene entirely, but rather limits its action to reducing the production of melanin in the iris – effectively “diluting” brown eyes to blue. The switch’s effect on OCA2 is very specific therefore. If the OCA2 gene had been completely destroyed or turned off, human beings would be without melanin in their hair, eyes or skin colour – a condition known as albinism. Limited genetic variation

Variation in the colour of the eyes from brown to green can all be explained by the amount of melanin in the iris, but blue-eyed individuals only have a small degree of variation in the amount of melanin in their eyes. “From this we can conclude that all blue-eyed individuals are linked to the same ancestor,” says Professor Eiberg. “They have all inherited the same switch at exactly the same spot in their DNA.” Brown-eyed individuals, by contrast, have considerable individual variation in the area of their DNA that controls melanin production.

Professor Eiberg and his team examined mitochondrial DNA and compared the eye colour of blue-eyed individuals in countries as diverse as Jordan, Denmark and Turkey. His findings are the latest in a decade of genetic research, which began in 1996, when Professor Eiberg first implicated the OCA2 gene as being responsible for eye colour. Nature shuffles our genes

The mutation of brown eyes to blue represents neither a positive nor a negative mutation. It is one of several mutations such as hair colour, baldness, freckles and beauty spots, which neither increases nor reduces a human’s chance of survival. As Professor Eiberg says, “it simply shows that nature is constantly shuffling the human genome, creating a genetic cocktail of human chromosomes and trying out different changes as it does so.”


TOPICS: Culture/Society; Miscellaneous; News/Current Events; Technical
KEYWORDS: blueeyes; eugenics; evolution; genetic; genetics; godsgravesglyphs; helixmakemineadouble; incest; mutation
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To: NYer

Heh.


221 posted on 01/31/2008 9:51:00 AM PST by trisham (Zen is not easy. It takes effort to attain nothingness. And then what do you have? Bupkis.)
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To: Sherman Logan

“Both your parents carried a recessive gene for blue eyes. They had a four in one chance of any child having blue eyes.”

I always thought both my parents were idiots growing up.

Fortunately, there was a one in five chance of them creating a genius and here I am!


222 posted on 01/31/2008 10:10:49 AM PST by FastCoyote (I am intolerant of the intolerable.)
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To: colorado tanker

:’) No one will hold it against you.

Well, at least the OTHER FREAKS won’t. ;’) ;’) ;’)

Groups isolated on islands wind up with the same last name. It’s just how it winds up. The isolation concentrates and speeds up a process that is going on everywhere, but goes on mostly invisibly. Blue eyes are just easy to spot. A similar study would show common ancestry for everyone with kinky hair, or (perhaps) a given blood type (such as B, which is the least common major bloodtype; AB people would also have their B gene on chromosome 9 tested). This blue eye study is probably not done for political purposes, but will surely be twisted into such purposes.


223 posted on 01/31/2008 10:12:39 AM PST by SunkenCiv (https://secure.freerepublic.com/donate/__________________Profile updated Wednesday, January 16, 2008)
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To: EarthBound

Genetics.


224 posted on 01/31/2008 10:16:15 AM PST by MacDorcha (Do you feel that you can place full trust in your obsevations of the physical world?)
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To: GQuagmire

Actually, there are two types of eyes, dark and light. One of your parents probably had hazel eyes which can result in a blue eyed child. My mother and her mother had hazel eyes.


225 posted on 01/31/2008 10:21:03 AM PST by Mercat (Kennedys: Can't drive, can't swim, can't fly, can't ski, but they know what's best for us.)
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To: sodpoodle

>>That has to be David Bowie’s offspring. One brown, one blue eye.....

I seem to remember Bowie saying in an interview that his eyes aren’t actually different colors. In primary school, some bully smacked David in the head with a bottle or something for talking to his girlfriend. As a result, his iris is frozen open.


226 posted on 01/31/2008 10:27:52 AM PST by jus'plainjeff (Who in the.......?)
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To: jus'plainjeff

I had a childhood friend who had one green and one blue eye. On top of that, his pupils were diamond or slit shaped like a cat.


227 posted on 01/31/2008 10:42:21 AM PST by FishTale
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To: decimon

Adam...Noah


228 posted on 01/31/2008 11:18:24 AM PST by LiteKeeper (Beware the secularization of America; the Islamization of Eurabia)
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To: jmcenanly

3 Putins on the left, 3 Craigs on the right
(though with the KGB, you never know how many doubles Vlad may have...).


229 posted on 01/31/2008 11:30:40 AM PST by rfp1234 (Phodopus campbelli: household ruler since July 2007.)
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To: decimon
examined mitochondrial DNA

Actually, that makes them a busy girl...

230 posted on 01/31/2008 11:38:44 AM PST by HamiltonJay
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To: decimon
which neither increases nor reduces a human’s chance of survival.

Umm... Chances of survival have nothing to do with passing on genes. Chances of reproduction however... That's the ticket.

231 posted on 01/31/2008 11:51:59 AM PST by coconutt2000 (NO MORE PEACE FOR OIL!!! DOWN WITH TYRANTS, TERRORISTS, AND TIMIDCRATS!!!! (3-T's For World Peace))
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To: RockinRight; null and void; Lady Jag
Yesterday I found out that I'm black, and today I find out I'm married to a relative.

I wonder when the application form for Scientology is going to arrive.

232 posted on 01/31/2008 12:50:28 PM PST by fanfan ("We don't start fights my friends, but we finish them, and never leave until our work is done."PMSH)
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To: GQuagmire

As the only blue-eyed member of my family, I felt like a mutant. Now it’s confirmed.


233 posted on 01/31/2008 12:59:01 PM PST by Tired of Taxes (Dad, I will always think of you.)
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To: coconutt2000

In some recessive traits, being heterozygous (carrier state) infers resistance to certain infectious diseases. Examples include sickle cell anemia (malaria), cystic fibrosis (tuberculosis) and Tay-Sachs (typhoid).


234 posted on 01/31/2008 1:04:44 PM PST by CholeraJoe ("A dead whale or a stove boat!")
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To: aft_lizard

I’m sorry, it is true. You’ve been taught wrong. If you want to get really technical, even the blue pigment doesn’t exist. It’s the blood vessels that create the bluish color, just as some veins close to your skin appear blue if you have very pale skin.

Humans only have two pigment variations...brown and yellow(or gold, which is dark yellow). Green exists in reptiles and birds, but not mammals.


235 posted on 01/31/2008 3:11:08 PM PST by mamelukesabre
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To: decimon
Weird since brown is domanent.

?

I think Mama's old mailman had green eyes because all of my family has blue (I mean blue!) eyes except me. I got green.


236 posted on 01/31/2008 3:44:00 PM PST by bannie (clintons CHEAT! AAAALLWAYS!)
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To: Kozak

Mine are green...Parents’ are blue. Is my mama suspect?


237 posted on 01/31/2008 3:45:26 PM PST by bannie (clintons CHEAT! AAAALLWAYS!)
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To: fishtank

Wouldn’t two mates have blue?


238 posted on 01/31/2008 3:46:31 PM PST by bannie (clintons CHEAT! AAAALLWAYS!)
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To: decimon
BTW: None of my ancestors are common!


239 posted on 01/31/2008 3:48:20 PM PST by bannie (clintons CHEAT! AAAALLWAYS!)
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To: bannie
I think Mama's old mailman had green eyes because all of my family has blue (I mean blue!) eyes except me. I got green.

You came into this world Special Delivery?

240 posted on 01/31/2008 3:49:59 PM PST by decimon
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