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Stem cells create tumours, says expert
Herald Sun ^ | 10 October 2006 | Jane Bunce

Posted on 10/10/2006 2:38:30 AM PDT by Aussie Dasher

EMBRYONIC stem cells turn into tumours when injected into human tissue and therefore cannot be used to treat diseases, a visiting US expert said today.

Professor James Sherley, a researcher in the field of adult stem cells, is one of a series of experts in Canberra to lobby MPs ahead of a conscience vote on whether a ban on therapeutic cloning should be overturned.

Prof Sherley, from Boston's Massachusetts Institute of Technology (MIT), today said scientists had failed to reveal problems with embryonic stem cells that would prevent them being used in humans.

The unique feature of embryonic stem cells that allowed them to turn into any cell of the body, known as pluripotency, created a problem when researchers injected them into tissue, Prof Sherley said.

“When you put them in an environment where they can grow and develop, they make lots of different kind of tissues,” Prof Sherley said.

“This tumour formation property is an inherent feature of the cells.

“And all you have to do is simply inject them into an animal tissue – this happens at very high efficiency.

“And although some might say we can solve the tumour problem down the road, that's equivalent to saying we can solve the cancer problem and we may, but that's a long time coming.”

Prof Sherley said the tumours, called teratomas, were generally considered benign, but it was possible they could metastasize or produce chemicals such as enzymes and cytokines that affect other parts of the body.

(Excerpt) Read more at news.com.au ...


TOPICS: Australia/New Zealand; Crime/Corruption; Culture/Society; Extended News; Government; News/Current Events
KEYWORDS: australia; con; embryonicstemcells; embryos; jamessherley; stemcells; tumors; tumours
Enough with the false hope.

Embryonic stem cell research cures NOTHING!

1 posted on 10/10/2006 2:38:31 AM PDT by Aussie Dasher
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To: Aussie Dasher

Curing things was never the real issue. The real issue was an excuse to harvest baby parts.


2 posted on 10/10/2006 2:42:35 AM PDT by Always Right
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To: Aussie Dasher
I'd read accounts of this a couple of years ago. Funny how it doesn't get coverage. Well, National Review had a few articles, and pro-life organizations have reported it.

Once again, Australia -- well, not to be crude, but -- cuts the crap!

3 posted on 10/10/2006 2:43:55 AM PDT by maryz
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To: Aussie Dasher; cpforlife.org; narses

Pinging pro-lifers!


4 posted on 10/10/2006 2:47:00 AM PDT by maryz
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To: Aussie Dasher
Embryonic stem cell research cures NOTHING!

Are you a doctor/researcher or do you just play one on FR?

5 posted on 10/10/2006 2:48:15 AM PDT by zarf
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To: zarf

Neither but facts are facts!


6 posted on 10/10/2006 2:49:51 AM PDT by Aussie Dasher (The Great Ronald Reagan & John Paul II - Heaven's Dream Team!)
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To: Aussie Dasher

BTTT

Too bad Free Republic doesn't have a "sticky" function.


7 posted on 10/10/2006 2:52:28 AM PDT by UnbelievingScumOnTheOtherSide (Give Them Liberty Or Give Them Death! - IT'S ISLAM, STUPID! - Islam Delenda Est! - Rumble thee forth)
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To: Always Right
The real issue was an excuse to harvest baby parts.

I've always thought the real draw was transgressing taboos -- to do that which is abhorrent for its own sake.

BOR had a report a year or two ago about traffic in baby parts -- I think from aborted babies; they didn't need to wait for embryonic stem cell research for that.

8 posted on 10/10/2006 3:01:00 AM PDT by maryz
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To: Aussie Dasher

The key is that as much as we hate to admit it, not one of us is going to live forever, not in these bodies that all seem so destine to protect.


9 posted on 10/10/2006 4:32:38 AM PDT by hadaclueonce (shoot low, they are riding Shetlands.....)
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To: Aussie Dasher
Embryonic stem cell research cures NOTHING!

Well of course not. It's purpose is to create another massive industry - not unlike the education industry that controls our schools - that is taxpayer funded and filled with Democrat voters.

It's the same plan, over and over again. Tax the wealth away from your political opponents and disperse it among your constituents all in the name of "social justice."

10 posted on 10/10/2006 4:36:37 AM PDT by Texas Jack
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To: zarf
Are you a doctor/researcher or do you just play one on FR?

Thanks.....I needed coffee shooting out of my nose. LOL!!

11 posted on 10/10/2006 5:28:48 AM PDT by Puppage (You may disagree with what I have to say, but I shall defend to your death my right to say it)
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To: maryz
From my files:

Embryonic stem cells have not cured or successfully treated a single patient. Contrast that with the more than 70 conditions that are treatable using non-embryonic stem cell therapies.

Note: Conditions treatable using non-embryonic stem cells are listed in this article.

Adult Stem Cells: It's Not Pie-in-the-Sky

Though embryonic stem cell research advocates euphemistically refer to the current state of research as an “early stage”, the unfortunate reality is the goal of embryonic stem cell therapies is, at this point, more accurately described as a pipe dream. No researcher is anywhere close to significant progress in developing practical embryonic stem cell therapies.

The only thing certain is that the cost of that research will be high. If embryonic stem cell research had real and imminent possibilities, private investors would be pouring capital into research hoping for real and imminent profits. Instead, venture capital firms are contributing to political efforts to get taxpayers to fund research. What the venture capitalists seem to be hoping for is that taxpayer funding of stem cell research will increase the value of their stakes in biotech companies. The venture capitalists can then cash out at a hefty profit, leaving taxpayers holding the bag of fruitless research.

Ron Reagan Wrong on Stem Cells

"Using embryonic stem cells, researchers at Stanford University who are working on a cure for Type I diabetes are producing new pancreatic islet cells that could be used in human transplants and could herald a cure for this devastating illness."

Actually, the latest research findings regarding embryonic stem cells are that they do not actually produce insulin in response to glucose changes in their environment and are NOT the pancreatic beta cells needed to treat diabetes. When placed in animals, the cells did not reverse diabetes; instead, they formed tumors.

"A Korean research team recently made history by using human embryonic stem cells to cure Parkinson's disease in rats."

That is what they claim, but the research is a long way from producing a safe and effective treatment for humans. On the one known occasion when earlier-stage (before 6 weeks) fetal tissue was used to try to treat a human Parkinson's patient, the tissue killed the patient by forming clumps of bone, skin and hair in the middle of his brain.

Moreover, animal trials with embryonic stem cells repeatedly kill many of the animals because of formation of brain tumors.

Meanwhile, the first clinical trial using a patient's own adult brain stem cells to treat Parkinson's has produced a lasting 80% reversal of symptoms, and wider human trials are being planned.

New Jersey Right to Life

12 posted on 10/10/2006 7:17:34 AM PDT by ravingnutter
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To: Aussie Dasher
Prof Sherley, from Boston's Massachusetts Institute of Technology (MIT), today said scientists had failed to reveal problems with embryonic stem cells that would prevent them being used in humans.

Gee, I wonder why. Is is because the scientific inquiry has been hijacked by political cause?

13 posted on 10/10/2006 8:40:34 AM PDT by the invisib1e hand (* nuke * the * jihad *)
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To: Puppage
Prof Sherley, from Boston's Massachusetts Institute of Technology (MIT), today said scientists had failed to reveal problems with embryonic stem cells that would prevent them being used in humans.

Surely he can't be serious!

14 posted on 10/10/2006 8:43:50 AM PDT by dfwgator
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To: Coleus; nickcarraway; narses; Mr. Silverback; Canticle_of_Deborah; TenthAmendmentChampion; ...
Pro-Life PING

Please FreepMail me if you want on or off my Pro-Life Ping List.

15 posted on 10/10/2006 4:48:27 PM PDT by cpforlife.org (A Catholic Respect Life Curriculum is available at KnightsForLife.org)
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To: 2ndMostConservativeBrdMember; afraidfortherepublic; Alas; al_c; american colleen; annalex; ...

Prof Sherley said the tumours, called teratomas, were generally considered benign, but it was possible they could metastasize or produce chemicals such as enzymes and cytokines that affect other parts of the body.


16 posted on 10/10/2006 8:54:50 PM PDT by Coleus (Abortion and Euthanasia, Don't Democrats just kill ya!)
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To: Aussie Dasher

"EMBRYONIC stem cells turn into tumours when injected into human tissue and therefore cannot be used to treat diseases, a visiting US expert said today."

What a fitting outcome for people who have NO REGARD for life.


17 posted on 10/10/2006 9:10:23 PM PDT by nmh (Intelligent people recognize Intelligent Design (God) .)
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To: Coleus; Peach; airborne; Asphalt; Dr. Scarpetta; I'm ALL Right!; StAnDeliver; ovrtaxt

bump & a ping


18 posted on 10/10/2006 9:52:16 PM PDT by neverdem (May you be in heaven a half hour before the devil knows that you're dead.)
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To: Always Right

Also an excuse to get on the government handout wagon.

If it were profitable private industry would be all over this just like they are on adult stem cell research.

It showed no promise of return on investment.


19 posted on 10/10/2006 10:09:45 PM PDT by TASMANIANRED (The Internet is the samizdat of liberty..)
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To: Aussie Dasher

tumours? oh, bothour!


20 posted on 10/10/2006 10:11:53 PM PDT by HiTech RedNeck
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To: Aussie Dasher

Who has the scoreboard? Embryonic stem cells has a negative score now.


21 posted on 10/11/2006 7:10:19 AM PDT by I'm ALL Right! (There's a fine, fine line between a stoat and a sporkweasel.)
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To: maryz
Once again, Australia -- well, not to be crude, but -- cuts the crap!

I agree!!

22 posted on 10/11/2006 7:35:52 AM PDT by syriacus (Pelosi, 1998 - "It's about sex. It's about a punishment searching for a crime that doesn't exist.")
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To: nmh
What a fitting outcome for people who have NO REGARD for life.

Reaping what they sow.

23 posted on 10/11/2006 7:37:11 AM PDT by syriacus (Pelosi, 1998 - "It's about sex. It's about a punishment searching for a crime that doesn't exist.")
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To: Aussie Dasher
Scientist: Racism hurt him at MIT Says key example is tenure being denied By Marcella Bombardieri and Gareth Cook, Globe Staff  |  January 14, 2005
The son of a Baptist minister, Sherley is vocal in his opposition to research using human embryonic stem cells because he thinks this amounts to sacrificing human lives. This stand puts him at odds with most of his scientific colleagues -- and once prompted a shouting match with another scientist at a faculty dinner at the Blue Room, a Cambridge restaurant, he said. [snip]

After a faculty dinner devolved into a shouting match about the relative merits of embryonic and adult stem cells, he said he was no longer invited to the dinners. Slowly, he said, he became more and more ostracized, and the atmosphere become more poisonous. .


24 posted on 10/11/2006 7:50:52 AM PDT by syriacus (Pelosi, 1998 - "It's about sex. It's about a punishment searching for a crime that doesn't exist.")
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To: syriacus
Just last year, Sherley had been unable to obtain tenure at MIT, and not invited to Blue Room dinners with colleagues, but now MIT touts his ability to win awards.

Two MIT scientists win 2006 Pioneer Awards Elizabeth A. Thomson, News Office September 19, 2006

Two MIT faculty are among 13 scientists nationwide to receive 2006 Pioneer Awards today from the National Institutes of Health for their "highly innovative research."

Professors Arup K. Chakraborty and James L. Sherley will each receive $2.5 million over five years. [snip]

Sherley, an associate professor of biological engineering affiliated with the Center for Cancer Research, is working "to develop routine methods for the production of human adult stem cells from liver, pancreas, hair follicles and bone marrow."


25 posted on 10/11/2006 8:02:48 AM PDT by syriacus (Pelosi, 1998 - "It's about sex. It's about a punishment searching for a crime that doesn't exist.")
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To: syriacus
Looks like the students at MIT recognized Sherley's attributes, even if the faculty and administration didn't
Professor Sherley is a great professor and researcher. Although I have only known him for a year, I can easily say that he has had the greatest impact on me of any of the professors here, and I don't think that my experience is a unique one. Regardless of how busy he is, he always make time for his students. I am always impressed at his enthusiasm for his research and the research of his students. He has really set an example by standing up for his beliefs and not letting the majority rule, whether it be in opposing embryonic stem cell research, or in asking that MIT re-examine how his tenure case has been treated. I ask you to take a careful look at his tenure case and the issues surrounding it, and if you find that his case has been unfairly treated, please send it on to the Engineering committee.

26 posted on 10/11/2006 8:09:55 AM PDT by syriacus (Pelosi, 1998 - "It's about sex. It's about a punishment searching for a crime that doesn't exist.")
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To: syriacus
More student accolades for Sherley
Dr. Sherley was assigned to me as my freshmen advisor and since then I have come to respect him as a mentor, professor, and scientist. When I chose to become an associate advisor, I specifically asked to be a part of his freshmen advising/seminar group because I had had a great experience with him as a freshman. He goes out of his way to truly get to know his students at a time when they need guidance and help adjusting to college. Dr. Sherley is also an outstanding pre-medical advisor who, as an MD/PhD, can offer personal advice to students wanting to pursue a career in medicine, science, or both. When I look back at my years at MIT, I remember not only the great education I received but the people who made it enjoyable. I can honestly say Dr. Sherley is one of a handful of professors who I am grateful to have met and gotten to know. I sincerely hope MIT re-examines this decision and proceeds to have his tenure package reviewed by the Engineering Council.

27 posted on 10/11/2006 8:12:32 AM PDT by syriacus (Pelosi, 1998 - "It's about sex. It's about a punishment searching for a crime that doesn't exist.")
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To: Always Right
The real issue was an excuse to harvest baby parts.

And use lots of grant money....

28 posted on 10/11/2006 8:12:38 AM PDT by Smokin' Joe (How often God must weep at humans' folly.)
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To: syriacus
MIT STEM CELL PROFESSOR LASHES THERAPEUTIC CLONING
Fear of reprisals is one reason why some scientists do not oppose therapeutic cloning says a professor at the prestigious Massachusetts Institute of Technology. Associate Professor James Sherley says that "I have asked the leaderships of both the American Society for Cell Biology and the International Society for Stem Cell Research to conduct anonymous on-line polls of their membership regarding their views on human embryo research. Neither has been willing to do so. Many scientists who do not support human embryo research are afraid to speak out because of possible reprisals from powerful scientists who can affect grant success, publication acceptances, tenure promotion, and employment."

Professor Sherley is an expert in adult stem cells and an outspoken critic of embryonic stem cell research because, he argues, it is ethically and scientifically flawed. Not mincing his words, he says that many researchers "can often turn an amazingly blind eye to the contradictions in their position on therapeutic cloning. For example, the same scientists who argue that reproductive cloning would produce disease-ridden individuals insist that tissues created from therapeutic cloning will function normally!"

Cures will come from adult stem cells, he predicts. "It is pure scientific folly to place such emphasis on embryonic stem cells research to the exclusion of support for adult stem cell research," he says. "No matter what the hurdles are for success with adult stem cell-based therapy development, embryonic stem cell research faces the same hurdles and more." ~ MercatorNet, Dec 6 (disclosure: this magazine is also edited by the editor of BioEdge)

  
29 posted on 10/11/2006 8:17:13 AM PDT by syriacus (Pelosi, 1998 - "It's about sex. It's about a punishment searching for a crime that doesn't exist.")
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To: neverdem

bump


30 posted on 10/11/2006 9:03:34 AM PDT by Dr. Scarpetta
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To: Dr. Scarpetta

Cancer's the flip side of life's coin? Who woulda thunk it?


31 posted on 10/11/2006 10:58:56 AM PDT by GOPJ (Zucker ad mocking democrats: http://www.youtube.com/watch?v=7h3GPc_yMCE)
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To: Always Right

And deny that life begins at conception - a pro-choice tool


32 posted on 10/11/2006 11:01:54 AM PDT by fml
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To: Aussie Dasher
It is interesting that a group of related articles will appear at once. If it is something like a N Kor atomic (maybe!) test this is understandible, but this one and the in vitro, ex cathedra opinion go together like they came from the same medical conference.
33 posted on 10/11/2006 11:04:06 AM PDT by RightWhale (Repeal the law of the excluded middle)
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To: Big Giant Head

More ammunition for you, dear. :-D


34 posted on 10/11/2006 12:10:47 PM PDT by Marie Antoinette (Proud Clinton-hater since 1998. Sporkweasels Up!)
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