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Synthetic Windpipe Is Used to Replace Cancerous One
NY Times ^ | January 12, 2012 | HENRY FOUNTAIN

Posted on 01/15/2012 9:43:14 PM PST by neverdem

Surgeons in Sweden have replaced the cancerous windpipe of a Maryland man with one made in a laboratory and seeded with the man’s cells.

The windpipe, or trachea, made from minuscule plastic fibers and covered in stem cells taken from the man’s bone marrow, was implanted in November. The patient, Christopher Lyles, 30, whose tracheal cancer had progressed to the point where it was considered inoperable, arrived home in Baltimore on Wednesday. It was the second procedure of its kind and the first for an American.

“I’m feeling good,” Mr. Lyles said in a telephone interview from his home, where he was playing with his 4-year-old daughter. “I’m just thankful for a second chance at life.” He said he hoped to resume his job, as an electrical engineer with the Department of Defense, as soon as he regained full strength.

“He went home in very good shape,” said Dr. Paolo Macchiarini, director of the Advanced Center for Translational Regenerative Medicine at the Karolinska Institute in Stockholm.

Dr. Macchiarini is a leader in the field of tissue engineering, in which the goal is to produce replacement tissues and organs outside the body. Research in the field has undergone a resurgence in recent years because of advances in understanding stem cells — undifferentiated cells that can proliferate and be induced to become cells of a specific type of tissue.

“What we did is surgically remove his malignant tumor,” Dr. Macchiarini said. “Then we replaced the trachea with this tissue-engineered scaffold.” The Y-shaped scaffold, fashioned from nano-size fibers of a type of plastic called PET that is commonly used in soda bottles, was seeded with stem cells from Mr. Lyles’s bone marrow. It was then placed in a bioreactor — a shoebox-size container holding the stem cells in solution — and rotated like...

(Excerpt) Read more at nytimes.com ...


TOPICS: Culture/Society; Extended News; News/Current Events; Technical; US: Maryland
KEYWORDS: adultstemcells; maryland; regenerativemedicine; stemcells; sweden; windpipe

1 posted on 01/15/2012 9:43:20 PM PST by neverdem
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To: Coleus; Peach; airborne; Asphalt; Dr. Scarpetta; I'm ALL Right!; StAnDeliver; ovrtaxt; ...

FReepmail me if you want on or off my stem cell ping list.


2 posted on 01/15/2012 9:46:01 PM PST by neverdem (Xin loi minh oi)
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To: neverdem
Bladder for the 17 year old girl. Trachea for this guy.

It seems likely that if I want to pay for it, and go through the trouble, in a few years they well be able to replace my missing left kidney and maybe my spleen. (not that I really miss either)

/johnny

3 posted on 01/15/2012 10:02:54 PM PST by JRandomFreeper (Gone Galt)
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To: neverdem
made from minuscule plastic fibers

PVC pipes? Cool.

Although I wonder why they are still working on medical miracles when in a few years, they will just let us all die if it is too expensive for us to be saved.

4 posted on 01/15/2012 10:05:30 PM PST by Defiant (President Odinga is setting the stage for chaos in the streets. Obey!)
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To: Defiant
Just to let us die anyway"""

Good point. STOP obama/romneycare now.

5 posted on 01/15/2012 10:19:15 PM PST by annieokie
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To: annieokie

This is pretty amazing; they have done this in the past with a body part that had been stripped of everything except the structural material (collagen?).


6 posted on 01/15/2012 10:41:14 PM PST by The Antiyuppie ("When small men cast long shadows, then it is very late in the day.")
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To: The Antiyuppie

It truly is amazing, I agree. But the point was with Romney/Obamacare who will be able to use it, certainly not the little people.


7 posted on 01/15/2012 10:43:56 PM PST by annieokie
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To: Defiant
PVC pipes? Cool.

PVC is polyvinyl chloride. I'm pretty sure that PET means Polyethylene Terephthalate in this case. It's used for plastic bottles.

8 posted on 01/15/2012 10:46:25 PM PST by neverdem (Xin loi minh oi)
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To: neverdem

I may need to get me one of those.


9 posted on 01/15/2012 11:21:57 PM PST by smokingfrog ( sleep with one eye open (<o> - - -)
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To: JRandomFreeper
"rotated like a rotisserie chicken to allow the cells to soak in."

WOW! Who would have thought. Can you imagine your kidney and spleen rotating on a chicken rotisserie waiting to be installed.

10 posted on 01/15/2012 11:40:31 PM PST by Orange1998
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To: Orange1998

“WOW! Who would have thought. Can you imagine your kidney and spleen rotating on a chicken rotisserie waiting to be installed.”

Just as long as they aren’t cooking it to eat it.


11 posted on 01/16/2012 12:26:24 AM PST by flaglady47 (When the gov't fears the people, liberty; When the people fear the gov't, tyranny.)
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To: JRandomFreeper

Will artificial spleens have vents built in to them, so you can vent your spleen at will? (duck’n & runn’n)


12 posted on 01/16/2012 1:19:03 AM PST by HiTech RedNeck (Sometimes progressives find their scripture in the penumbra of sacred bathroom stall writings (Tzar))
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To: flaglady47

Liver with fava beans and a nice Chianti?


13 posted on 01/16/2012 2:07:02 AM PST by NY.SS-Bar9
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To: NY.SS-Bar9

and a nice MAO inhibitor, makes you blow your top! (literally)


14 posted on 01/16/2012 3:07:55 AM PST by HiTech RedNeck (Sometimes progressives find their scripture in the penumbra of sacred bathroom stall writings (Tzar))
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To: flaglady47

LOL.... I wonder, would someone say its taste like chicken.


15 posted on 01/16/2012 4:07:34 PM PST by Orange1998
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To: neverdem; Abundy; Albion Wilde; AlwaysFree; AnnaSASsyFR; bayliving; BFM; cindy-true-supporter; ...

Wow. Good for him.

Maryland “Freak State” PING!


16 posted on 01/17/2012 8:17:47 PM PST by Tolerance Sucks Rocks (Occupy DC General Assembly: We are Marxist tools. WE ARE MARXIST TOOLS!)
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