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Destroying senescent cells in the aging stem cell niche enhances hippocampal neurogenesis and cognitive function in mice, researchers report. "Our results provide further support for the notion that excessive senescence is a driving factor behind aging, and even late-life reduction of these cells can rejuvenate and restore the function of the stem cell niche," says senior author David Kaplan. "Moreover, they identify stem cells as a key cellular target, potentially explaining the widespread effects of senescent cells on tissue decline." Senescent cells, which are permanently arrested because of chronic stress, are partly responsible for tissue decline during aging. "Stem cells...

An oral supplement intended to stimulate a natural body process appears to promote muscle endurance and mitochondrial health in humans. New research suggests that the supplement, urolithin A, may help improve or prolong muscle activity in people who are aging or who have diseases that make exercise difficult. Urolithin A is a byproduct of a person's gut bacteria and a diet comprising polyphenols found in pomegranates, berries and nuts. The compound also is produced and sold by dietary supplement companies. Supplemental urolithin A has been shown in animal tests and molecular studies of humans to stimulate mitophagy, a process that...

New atrial fibrillation drugs possess significant advantages over warfarin for reducing the risk of embolic events such as a stroke or peripheral embolism. Patients with AFib have an especially high risk of blood clots that can lead to stroke. Warfarin (Coumadin) has been the gold standard for stroke prevention in patients with AFib for the past 50 years. But to be effective, warfarin requires careful monitoring. Within the last several years, the FDA has approved several new anticoagulants as alternatives to warfarin: dabigatran (Pradaxa), a direct thrombin inhibitor; rivaroxaban (Xarelto), a factor Xa inhibitor; and apixaban (Eliquis), also a factor...

A 74-year-old woman now holds the record for “world’s oldest mom” after she reportedly gave birth to twins on Thursday following a round of in vitro fertilization using donor eggs. The woman, identified as Erramatti Mangayamma, and her husband, 80-year-old Rajarao, hail from a small Indian village in the Eastern Godavari district, SWNS reported.

Is Elizabeth Warren having an extramarital affair with New York Magazine? I ask only because NYM just published a 7,200-word opus that reads like a deranged love letter to the American Native senator from Massachusetts, seeking to turn an old, wrinkled leftist with even older, more wrinkled leftist ideas into the fresh young face for America in 2020. Read more: https://www.americanthinker.com/blog/2018/07/lib_media_try_to_make_liz_warren_the_fresh_young_face_for_2020.html#ixzz5MAIjgRXF Follow us: @AmericanThinker on Twitter | AmericanThinker on Facebook

Hillary tells India

Hillary Clinton, appearing Tuesday at a townhall in Keota, Iowa, had a hard time understanding a young voter asking about immigration. The voter introduced herself and began asking a question about the ICE's "reputation" for deporting low-priority immigrants and poor treatment of women. "Can you just slow down a little bit, I'm having a hard time," Clinton interjected. The young woman did not appear to be speaking abnormally quickly. "I want to hear you, so just slow down a little," Clinton repeated. The voter then asked about Pastor Max Villatoro who was deported to Honduras after convictions for drunken driving...

We wrote here about Harry Reid’s supposed close encounter with a piece of exercise equipment, which handed him in the hospital. The equipment was later claimed by Reid’s office to be an elastic exercise band. This is how the accident allegedly happened: The accident happened when an elastic exercise band broke, striking Reid in the face and causing him to fall, said spokesman Adam Jentleson. Reid struck some equipment as he fell, breaking multiple bones near his right eye. As he hit the floor, he broke several ribs, Jentleson said. … Jentleson said Reid is likely to have severe facial...

The average age of members of the U.S. Senate is older than it has ever been, according to Senate Historian Richard Baker. For many senators, advanced age is starting to show, raising questions about their ability to govern. Until his retirement last month, former majority leader Bill Frist, R-Tenn., a noted heart surgeon, was being consulted for informal medical advice by two dozen of his colleagues -- more than 20 percent of the Senate, according to a former leadership aide. They went to Frist complaining about a host of illnesses and chronic maladies, most related to aging. Among them were...

Germany's three oldest bank robbers were jailed yesterday after admitting they stole more than €1.2 million ($1.9 million) in 14 raids across a number of provincial towns. The men, who became known as the "Grandpa Gang", started their spree in 1988 and were arrested last year when police set a trap. A court in Hagen sentenced 74-year-old Rudolf Richter - known as Rudi - together with Wilfried Ackermann, 73, and Lothar Ackermann, 64, to between nine and 12 years in jail. Most of the robberies went without a hitch, but the court was told that, on one occasion during an...

CONROE, Texas — Viva McGary McComb, a descendant of a Battle of San Jacinto soldier and a Texas legislator who helped establish the University of Texas, has died. She was 110. Born in Houston on March 29, 1894, McComb died Thursday, just days before the Conroe Pan American Round Table, which she founded in 1949, planned to recognize her as the oldest living Texan at its state convention in El Paso this weekend. "The Pan American Round Table was one of her great loves," said Jeanette Defee, one of five representatives of the Conroe chapter. "She was a brilliant woman,...

Bruce Springsteen, REM, and more tour for political change. SEATTLE, WA.  Friday 8.6.2004  /netmusiccountdown.com/ -- Is political change in the air for the USA? Artists like Bruce Springsteen and the E Street Band, REM, John Mellencamp, Babyface, John Fogerty, The Dave Matthews Band, Ben Harper, Pearl Jam and the Dixie Chicks hope so. These musicians, along with James Taylor, Bonnie Raitt, Jurassic 5, Keb' Mo', Bright Eyes, Death Cab for Cutie and My Morning Jacket, have formed a coalition of musicians who make up the Vote For Change Tour. Presented by MoveOn PAC, the tour launches October 1, one month before the...

Investigations The tyrant withinMost relevant passages have been boldened -------------------------------------------------------------------------------- This February Mark Lilla sat on a New York University panel about 9/11 and was shocked to hear a fellow panelist, the French intellectual Jean Baudrillard, "offering his fanciful take on the attack as a [symbolic] suicide by the towers." Lilla recalled the moment recently while keynoting a U of C Women's Board luncheon. "An act of suicide by the towers-because of the evils of capitalism and globalism and despite the loss of life-was actually, according to this respected intellectual, a predictable thing." Lilla, a professor in the Committee on...

<p>Mother Ruby Muhammad had hoped to get her watermelons and summer annuals into her Sacramento County garden before a trip to Chicago. But there hadn't been enough time.</p> <p>And she'd like to write another poem.</p> <p>At 106, Mother Ruby is downright vivacious. She was sad for a friend who confided to her that she was just waiting for the Lord to take her to heaven.</p>

Texas Legal FReepers, I need your help. In very brief: my grandfather's second wife (of around five years; they're in their early 90s) has more or less abandoned him. She misrepresented herself as quite well-off, and after they were married, come to find out she's not all that moneyed. That wouldn't be a problem, except she's bankrupted him. My grandfather retired from Shell in 1976, and between his pension and his investments, he saved up a VERY nice nest egg for him and my grandmother. After she left us and he remarried, everyone thought they'd live inside their income just...