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One in 500 men may carry an extra sex chromosome (most without knowing it)
Live Science ^ | June 15, 2022 | Nicoletta Lanese

Posted on 06/26/2022 10:55:44 AM PDT by SunkenCiv

As many as one in 500 men may carry an extra sex chromosome — either an X or a Y — but very few of them likely know about it...

The research, published June 9 in the journal Genetics in Medicine(opens in new tab), included data from more than 207,000 men who provided information to the U.K. Biobank, a repository of genetic and health data from half a million U.K.-based participants. Typically, males carry one X- and one Y-shaped sex chromosome in each of their cells, but among the study participants, there were 213 men who carried an extra X chromosome and 143 that had an extra Y.

Very few of these men either reported being diagnosed with a chromosomal abnormality or had such an abnormality noted in their medical records: Of the XXY men, only 23% had a known diagnosis, and just 0.7% of the XYY men had a diagnosis. (The potential symptoms of having an extra Y chromosome can be very subtle, which may somewhat explain the difference in diagnosis rates, according to the Genetic and Rare Diseases Information Center(opens in new tab).)...

Previous estimates suggested that roughly 100 to 200 men out of every 100,000 are XXY, according to the National Human Genome Research Institute(opens in new tab), and an estimated 18 to 100 out of every 100,000 were thought to be XYY, the authors noted in their report.

In all, about 0.17% of the study participants had an extra sex chromosome, or about one in 580. However, the rate observed in the study might be slightly lower than that among the general population, the study authors noted in their report. That’s because U.K. Biobank volunteers tend to be healthier than the general population and have a lower-than-average incidence of genetic conditions.

(Excerpt) Read more at livescience.com ...


TOPICS: History; Science; Travel
KEYWORDS: chromosomes; godsgravesglyphs; helixmakemineadouble; klinefeltersyndrome; nicolettalanese; science
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To: Jewbacca
am rather hirsute

Who knew? Screen names are more literal than people might ever suspect! :)

I figured that this was a description of Esau:

Setaceous Hebrew character

The forewings of this species are reddish brown with distinctive patterning towards the base; a black mark resembling the Hebrew letter nun (נ) with a pale cream-coloured area adjacent to this mark. The hindwings are cream coloured.


21 posted on 06/26/2022 11:27:18 AM PDT by Ezekiel (🆘️ . . . - - - . . . "Come fly with US". Ingenuity -- because the Son of David begins with Mars ♂️)
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To: SunkenCiv

I know there is a case out of Russia (see the movie Citizen X) where a man has one set set of DNA yet his sperm has a different DNA. Hardcore movie but it was very close to the actual events in history of a serial rapist/killer.


22 posted on 06/26/2022 11:28:17 AM PDT by Conservative4Life (thy merchants were great men of the earth; for by thy sorceries were all nations deceived. Rev18:23)
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To: Mount Athos
No, "Pyjama Boy" is missing a sex chromosome!

Regards,

23 posted on 06/26/2022 11:28:37 AM PDT by alexander_busek (Extraordinary claims require extraordinary evidence.)
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To: SunkenCiv
The nature of the double helix can be discerned through how the single non-helix gets used...

https://www.buzzfeed.com/crystalro/women-will-outlive-men

LOL!! Mrs. P will love those pics. She already believes the men in my family are descended from apes, and not that many generations removed.

24 posted on 06/26/2022 11:28:43 AM PDT by Perseverando (Antifa, BLM, RINOs, Islamonazis, Marxists, Commucrats, DemoKKKrats: It's a Godlessness disorder!)
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To: Mount Athos

25 posted on 06/26/2022 11:29:14 AM PDT by PGR88
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To: SunkenCiv

Well crap. You know what that means right. Some lib womxn is gonna complain they were denied the opportunity to have extra. Damn! 😂🙌


26 posted on 06/26/2022 11:31:36 AM PDT by rktman (Destroy America from within? Check! WTH? Enlisted USN 1967 to end up with this? 😕)
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To: SunkenCiv

Were they sampling a bunch of women who dressed and acted like men when they came to this conclusion?????


27 posted on 06/26/2022 11:32:57 AM PDT by Presbyterian Reporter
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To: SunkenCiv

at this point in life, I could use one*

(* at least one, smile smile smile)

are they on sale at walmart.com?


28 posted on 06/26/2022 11:37:03 AM PDT by faithhopecharity (“Politicians are not born. They’re excreted.” Marcus Tillius Cicero (106 to 43 BCE))
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To: SunkenCiv

A contact high from Chuck Barris, maybe. I saw a rerun of “My Three Sons” the other day. Jaye P. Morgan was in it. I thought, “ Oh, that’s what she did before “ The Gong Show.”


29 posted on 06/26/2022 11:39:19 AM PDT by gundog ( It was a bright cold day in April, and the clocks were striking thirteen. )
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To: gundog

I saw boobies!!!!


30 posted on 06/26/2022 11:43:10 AM PDT by BreezyDog
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To: Diana in Wisconsin

Why would I tip my waitress? That could cause her serious injury!


31 posted on 06/26/2022 11:50:09 AM PDT by Tolerance Sucks Rocks (Bus No. 2525)
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To: Mount Athos

XXY is known as Kleinfelder’s syndrome. Could be the case with Mr. Krupp, I suppose.


32 posted on 06/26/2022 11:52:01 AM PDT by Tolerance Sucks Rocks (Bus No. 2525)
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To: SunkenCiv

I don’t keep an eye on my chromosomes to be sure I have the right number.

Anyone who has a Y chromosome is a male.

The article does show clearly that secondary characteristics are linked to the chromosomes, and that chromosomes mean something. The Y determines if you are a male. Lack of the Y means you are a female.

The left is threatened by that statement of fact.


33 posted on 06/26/2022 11:52:59 AM PDT by I want the USA back (To get the USA back - we have to recover from the current wave of insanity.)
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To: Tolerance Sucks Rocks

Only posted pic for entertainment purposes, I’m sure there is no connection to reality. I think.


34 posted on 06/26/2022 11:55:32 AM PDT by Mount Athos
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To: aquila48
Damn, and I always check my chromosomes - how did that one escape me,

You probably stopped counting after you got to XY, figuring you were all set.
35 posted on 06/26/2022 12:05:35 PM PDT by Dr. Sivana (What was 35% of the Rep. Party is now 85%. And it’s too late to turn back—Mac Stipanovich )
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To: Jewbacca

The question that this begs is how does it affect fertility?


36 posted on 06/26/2022 12:14:23 PM PDT by DaxtonBrown
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To: SunkenCiv

I think it’s called Klinefelter syndrome. I knew a male who had it and he had (according to his wife) small testicles and he was infertile. (He had not told her of his condition before marriage, and unfortunately they eventually got divorced- for other reasons).


37 posted on 06/26/2022 12:22:44 PM PDT by Reddy ( B.O. stinks)
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To: SunkenCiv

Klinefelter syndrome and other sex chromosomal aneuploidies

The term Klinefelter syndrome (KS) describes a group of chromosomal disorder in which there is at least one extra X chromosome to a normal male karyotype, 46,XY. XXY aneuploidy is the most common disorder of sex chromosomes in humans, with prevalence of one in 500 males. Other sex chromosomal aneuploidies have also been described, although they are much less frequent, with 48,XXYY and 48,XXXY being present in 1 per 17,000 to 1 per 50,000 male births. The incidence of 49,XXXXY is 1 per 85,000 to 100,000 male births. In addition, 46,XX males also exist and it is caused by translocation of Y material including sex determining region (SRY) to the X chromosome during paternal meiosis. Formal cytogenetic analysis is necessary to make a definite diagnosis, and more obvious differences in physical features tend to be associated with increasing numbers of sex chromosomes. If the diagnosis is not made prenatally, 47,XXY males may present with a variety of subtle clinical signs that are age-related. In infancy, males with 47,XXY may have chromosomal evaluations done for hypospadias, small phallus or cryptorchidism, developmental delay. The school-aged child may present with language delay, learning disabilities, or behavioral problems. The older child or adolescent may be discovered during an endocrine evaluation for delayed or incomplete pubertal development with eunuchoid body habitus, gynecomastia, and small testes. Adults are often evaluated for infertility or breast malignancy. Androgen replacement therapy should begin at puberty, around age 12 years, in increasing dosage sufficient to maintain age appropriate serum concentrations of testosterone, estradiol, follicle stimulating hormone (FSH), and luteinizing hormone (LH). The effects on physical and cognitive development increase with the number of extra Xs, and each extra X is associated with an intelligence quotient (IQ) decrease of approximately 15–16 points, with language most affected, particularly expressive language skills.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1634840/


38 posted on 06/26/2022 12:24:04 PM PDT by FarCenter
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To: Diana in Wisconsin

I think they should look for the other missing letters in some people IQ.


39 posted on 06/26/2022 12:33:47 PM PDT by oldasrocks
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To: I want the USA back

There are XX males.

Normally when sperm are created, an XY germ cell divides into two sperm, one with an X and one with a Y.

When somatic chromosomes or XX pairs in the female divide, they swap sections of each chromosome in the pair when they produce two X eggs. In other words, each egg does not contain each the original Xs, but instead new, composite Xs.

When sperm is produced, this swapping of chromosome parts is not supposed to happen. However, by accident, part of a Y chromosome can be swapped into an X chromosome. When an egg is fertilized by this composite X sperm containing Y material, the resulting fertilized egg can develop into the male body type.


40 posted on 06/26/2022 12:39:18 PM PDT by FarCenter
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